Exam 3 Flashcards
- Nicotine
- Caffeine
- Alcohol
All have important social dimensions in addition to their physiological effects.
All of these are ___ ___
social drugs
- Marijuana
- Heroin and designer narcotics
- Cocaine
- Amphetamines
- Ecstasy
All of these are ____ ___ ___
common illegal drugs
- The most widely used psychoactive drug in the world
- Operates by competing with the inhibitory neuromodulator adenosine, increasing arousal.
- Serves as an adrenergic stimulant and a catecholamine agonist
- Catecholamines include dopamine, epinephrine, and norepinephrine
All of these are effects of ____
caffeine
- Increases both CNS and autonomic arousal.
- Reaches maximum blood levels about 30 minutes after ingestion
- Has 3-6 hour half life
Effects of ___
caffeine
- Heavy users report withdrawal symptoms if headache, fatigue, and more rarely depression, weakness, anxiety, nausea.
- Helps direct attention to spatial features of perceptual input
- Has limited effects on higher processing
Effects of ___
caffeine
May help maintain optimal levels of motor readiness, improves both choice and simple reaction times by decreasing time to initial response.
effects of __
caffeine
_____ : implicated in large numbers of car accident injuries and deaths
alcohol
Use beyond 8-12 oz of wine or 16-24 oz of beer a day a for women of 12-16 oz of wine or 24-32oz of beer a day for men considered ____
problematic.
___ impairs both cognitive and psychomotor performance
alcohol
_______ impairs visual pattern recognition and visual attention
alcohol
_______ impairs visual pattern recognition and visual attention
alcohol
Genetics Gender Age Habitual alcohol consumption Body size Health Mood
Factors affecting alcohol effects:
Driving limit is
.08%
_____ Impairs reaction time, narrows attention, increases risks taking
alcohol
Risk taking doubles with .04% blood ____ content
alcohol
Excessive use of ____ causes cognitive deficits, neurological damage
alcohol
Alcoholism can lead to ___ ____ in which a thiamine deficiency causes damage to the diencephalon, causes amnesia
Korsakoff’s disease
____ is the largest cause of preventable death in many countries
Smoking (Nicotine)
Smoking has declined to slightly more than __ of the population
¼
Nicotine is an ____ ___
acetylcholine agonist
____ ____ improve cognitive performance
Cholinergic agonists
Nicotine enters the system within about ___ _____
10 seconds
Nicotine increases performance strongly after ____ in users
abstinence
___ ______ ____ suggests this gain is due to alleviation of withdrawal symptoms that reduce performance
The Deprivation Reversal model
Smoking may _____ performance in the rapid visual information processing task
increase
Effects of smoking on learning and memory appear _____
inconsistent
___ ___ ____ ____ improve both visual and auditory signal detection, possible because of improved attention
Smoking and nicotine gum
Smokers smoke more than they drink, but were not sure if it counteracts ___ _____ _ ____
depressive effects of alcohol
___ may reduce some of the effects of very low doses of alcohol, but data on higher doses unclear
Caffeine
Caffeine and nicotine don’t appear to interact in any way except that both are used as ____
stimulants
THC attaches to cellular CB1, and cannabinoid receptors found on cell walls of neurons in the hippocampus and cerebellum, triggers dopamine release in the ___ ____
nucleus accumbens
_____: impairs speed and accuracy, seems to make time go faster, reduced ability to focus attention and ignore irrelevant information.
marijuana
____ impairs memory
THC
_____ : impairs speed and accuracy, seems to make time go faster, reduces ability to focus attention and ignore irrelevant information
____: use early in life associated with the greatest impairment
____: Deficits may be reversible.
marijuana
______ is a synthetic amphetamine
ecstacy
_____ Works as a monoamine agonist
ecstacy
___ related serotonin depletion may follow in the days after use
Ecstasy
___ has neurotoxic to serotonergic neurons
Ecstasy
ecstasy: Impairment of ___ _____ common in users, but causation is tricky and may be due to other drugs
working memory
Both Cocaine and Amphetamines can cause stimulant psychosis, with symptoms of paranoia and ____ ____
auditory hallucinations
Amphetamines ___ reaction time and alertness
improves
Cocaine _____ subjective sense of alertness but objective measures inconsistent
increases
cocaine abusers of both show ____ ____
cognitive deficits
amphetamine abusers show ____ in spatial working memory, pattern recognition, decision making, and shifting attention
deficits
cocaine abuses show problems with memory and language similar to symptoms of those with ___ ___ damage
frontal lobe
Prenatal exposure to cocaine associated with long term cognitive deficits, especially in ____ performance
motor performance
Prenatal exposure to ____ associated with long term cognitive deficits, esp. In motor performance
cocaine
_____ often called “narcotics”
opiates
____ kill pain, make people sleepy, reduce anxiety
opiates