Exam 3 Flashcards
eccentric hypertrophy:
volume loading
concentric hypertrophy
pressure loading
triggers for vasodilation in the heart:
- vasodilators released from cardiac cells with low O2
- NO released from coronary vessels from shear stress
how much O2 is extracted from arterial blood at normal resting HR?
70%
potent vasodilators:
- adenosine
- CO2
- NO
- H+
- K+
- prostaglandins
epicardial vessels have more _____ receptors:
alpha
intramuscular arteries have more ____ receptors
Beta
parasympathetic effect on coronary blood flow:
neurotransmitter: ACh
action: vasodilates coronary arteries
indirect effect:
-decrease HR, metabolic demand
-vasoconstriction
sympathetic effect on coronary blood flow:
neurotransmitter: NE
action: vasocontriction (alpha receptors)
indirect effect:
-increase HR, myocardial contractility, metabolic demand
-vasodilation
effect of epinephrine on coronary blood flow:
vasodilation (beta receptors)
-actions same as NE
a-VO2
- indicates oxygen uptake into the tissue
- bigger the difference the more oxygen that was extracted from the blood
HR max:
- responsiveness of heart to adrenergic stimulation
- no difference between the sexes
- no change with training
why does SV plateau between 50%-70% of VO2 max?
-decreased filling time
SVmax increases with training because:
- blood volume increases with aerobic training from kidney regulation
- more blood creates greater EDV
- increased EDV then greater contraction of heart
difference in gender for stroke volume?
SV in men greater than SV in women
increased sympathetic stimulation of alpha-receptors cause:
vasoconstriction
venous content for a-vO2 diff determined by:
- capillarity
- # open capillaries
- myoglobin
- mitochondrial density
- mitochondrial enzymes
byproducts that would cause vasodilation are:
adenosine
CO2
low O2 level