Exam 3 Flashcards
**What are three potential causes of dementia and examples of each?
Psychiatric (Depression)
Toxic/Metabolic (B12 Deficiency)
Vascular (Vasculitis)
What are the 5 cognitive or behavioral symptoms associated with dementia?
Inference with the ability to function usual activities
Represent a decline from previous levels of functioning
Not explained by any psychiatric disorder
Cognitive impairment is detected
Impaired in minimum of two ways: impaired reasoning, acquire and remember new information
Name three things you can do to help dementia?
Get evaluated by someone specialized in that field
Eat fruits and veggies
Antioxidants
What are antioxidants role in the brain in relation to dementia?
Look this up ad aa exam 3 slide 16
**What is cognitive reserve?
People who have higher education are more resistant to AD, than people who aren’t. They are smarter, then have more dendrites, and therefore can resist dementia-causing agents
Why is acute stress good?
Exercise is an acute stressor because it forms antioxidants, and triggers them to rid of it
When you wear the system out, then it’s no longer strong and able to cope
Acute stress teaches you to coach
Acute Inflamation- Mosquito bite, inflammation is good because its whats happening at a cellular level to fight it
If it was chronic that would be bad
The same thing happens with AD (Inflamaging)
Microglia and Astrocytes can react and create free radicals (H202 peroxide, it oxidizes your cut), when they do this it basically destroys the lipids, dna etc
*** 1907 study where they studies the brain of a 51 year old woman
He stained her brain and described the classical findings of fibrils in cells that are tangles together and amyloid plaques (which are classical pathological findings in AD)
Pathology of AD
Intracellular inclusion (aggregates) (primarily of the microtubule-associated protein tau in a hyperphosphorylated state) Extracellular inclusions of Beta-amyloid – derived from Amyloid Precursor Protein
What is the strongest evidence for the key role of amyloid in the pathogenesis of AD?
genetic evidence from families with APP mutations
What are the two genetic variables in AD?
don’t know how impt
Presenilin 1 on chromosome 14
Presenilin 2 on chromosome 1
What is mild cog. impairment (MCI)?
This is a research pool as well, but a middle ground for those who don’t quite classify as dementia
What is the cholinergic hypothesis of AD?
Acetylcholinesterase Inhibitors are used to possibly treat AD for a little while but in the end it doesn’t. Based off of
What is intelligence?
The application of knowledge
What is super intelligence?
Thinks outside the dots
Life span perspective on intelligence 4 factors:
Multidimensionality, multi directionality, plasticity, interindividual variability
Name and describe 2 life span perspective factors
Interindividual variability (people differ) Multidirectioanlity (many ways it develops over lifespan
IQ- testing cognitive structural approach
Assessment of ‘wisdom’ – i.e. how do you think and arrive at answers rather than the answers themselves or the score
IQ testing – psychometric approach
Tests whether you know it or not – less about the thought process
Age issues with IQ testing
As we age we change focus from accumulation of knowledge to application
To be successful one has to apply and adapt knowledge, not just give information back
Older adults IQ testing
Problem with OA (older adults) they have decreased sensation, perception, and they overall are slower so it’s not a good measure, Fewer test taking skills/ more anxiety
Motivation and IQ testing
We see in research that older adults are not motivated
Example- PRP (we as students want extra credit), older adults may get a Walmart card
Discussed stages from previous lesson as to why were more motivated
Its much easier for adults to get motivated on a subject that pertains to them (such as dementia
Factors of intelligence
When the responses correlate with each other you have less questions
For example, if five of the qs equal the other five then you can take them out
This saves time
Primary abilities
Relationship amongst performance on different intelligence tests
Word fluency – verbally describe objects
Primary abilities and age
Schaie’s work suggests that they decline around age 50-60some are faster –There is an increase between 25-40 and we don’t fall to the 25 year old level until 70s in some domains