Exam 3 Flashcards
3 basic types of movements
gliding
angular movements
rotation
what is gliding?
where does it occur?
nearly flat surfaces of 2 bones slip across each other
at joints between the carpals and tarsals and between flat articular processes of vertebrae
what are angular movements?
increase or decrease the angle between two bones
flexion, extension, abduction, adduction, circumduction
what is flexion?
give examples
decrease the angle between bones by bringing the bones closer together
- making a fist, bringing head forward, bringing arms forward
what is extension?
give examples?
increases the angle between the joining bones and is a straightening action
- straightening fingers after making a fist, bending head backwards, bringing leg back
what is abduction?
give examples
movement of a limb away from the body midline
- raising arm or thigh laterally, spreading fingers or toes apart
what is adduction?
give examples
movement of a limb towards the body midline
- bringing arm or thigh back towards the body laterally
what is circumduction?
moving a limb or finger so it describes a cone in space
(moving in a circle)
what is rotation?
give examples?
the turning movement of a bone around the longitudinal axis
- turning legs out
_____ is the only movement allowed between the first 2 cervical vertebrae
rotation
4 functional properties of muscle tissue that distinguish it from other tissues
1) contractility - actin and myosin create contractile force in every cell in the body
2) excitability - nerve signals or other stimuli excite muscle cells, causing electrical impulses to travel along the cells’ plasma membrane
3) extensibility - can be stretched, contraction of one skeletal muscle will stretch an opposing muscle
4) elasticity - after being stretched, muscle tissue recoils passively and resumes its resting length
describe skeletal muscle tissue
located in skeletal muscles, discrete organs that attach to and move the skeleton
- striated
- elongated, cylindrical cells
- voluntary movement
describe cardiac muscle tissue
occurs only in the wall of the heart
- striated muscle
- contractions are involuntary
describe smooth muscle
found in the hollow internal organs other than the heart
- lack striations
- cells are elongated
- involuntary movement
cardiac muscle and smooth muscle are collectively called _____ muscle
visceral
what is a sarcomere?
the contractile unit composed of myofilaments made up of contractile proteins
what is a myofilament?
contractile myofilaments have 2 types - thick and thin
- thick filaments contain bundled myosin molecules
- thin contain actin molecules plus the regular proteins troponin and tropomyosin
- the sliding of the thin filaments past the thick filaments produces muscle shortening
what is a myofibril?
rodlike contractile organelles that occupy most of the muscle cell volume
- composed of sarcomeres arranged end to end, they appear banded, and the bands adjacent myofibrils are aligned
what is a muscle fiber (cell)?
an elongated multinucleate cell
- has a banded (stiated) appearance
- surrounded by the endomysium
what is a fascicle?
a discrete bundle of muscle cells, segregated from the rest of the muscle by a connective tissue sheath
- surrounded by a perimysium
what is a muscle organ?
consists of hundreds to thousands of muscle cells, plus connecting tissue wrappings, blood vessels, and nerve fibers
- covered extenerally by the epimysium
what are the 3 connective tissues in and around a skeletal muscle
epimysium
perimysium
endomysium
describe the epimysium
outer layer of dense irregular connective tissue surrounding the whole skeletal muscle
describe the perimysium
within each skeletal muscle, the muscle fibers are separated into groups (fascicle)
surrounding each fascicle is a layer of fibrous connective tissue
describe the endoysium
within a fascicle, each muscle fiber is surrounded by a fine sheath of loose connective tissue consisting mostly of reticular fibers
what is an origin?
the attachment of the muscle on the less movable bone
what is an insertion?
attachment on the more lovable bone
when a muscle contracts, the ____ is pulled towards the ____
insertion
origin
what is a direct attachment?
the attaching strands of connective tissue are so short that the muscle fascicles themselves appear to attach directly to the bone
what is an indirect attachment?
the connective tissue extends well beyond the end of the muscle fibers to form either a cordlike tendon or a flat sheet called an aponeurosis
- more common than direct
the light and dark bands on muscle fibers are a result of rod-shaped organelles called _____
myofibrils
a myofibril is composed of repeating segments called _____
sarcomeres
the boundaries at the 2 ends of the sarcomere are called _____
Z discs
Attached to each Z disc are extending towards the center of the sarcomere are many fine myofilaments called _____
thin (actin) filaments
the thin filaments are composed primarily of the contractile protein _____
two regulatory proteins, _____ and ______ are also found
actin
troponin
tropomyosin
what is tropomyosin?
forms a thin strand that spirals around the actin molecule
what is troponin?
a globular protein with 3 binding sites:
- one for actin
- one for tropomyosin
- and one for calcium
- attaches the tropomyosin strand to the actin molecule
in the center of the sarcomere and overlapping the inner ends of the thin filaments is a cylindrical bundle of _____
thick (myosin) filaments
what is ATPase and where does it come from?
an enzyme that splits ATP to release the energy required for muscle contraction
thick (myosin) filaments
the dark bands of a sarcomere, along the ends of the thin filaments, which overlap the thick filaments is called the _____
A band
the central part of the A band where no thin filaments reach is the _____
H zone
the _____ is the center of the H zone that contains tiny rods that hold the thick filaments together
M line
the two regions on either side if the A band, regions that contain only thin filaments are called _____
I bands
the _____ of the sarcomeres create the light portions of the light-dark pattern of striations seen along the length of any skeletal muscle
I bands
describe the sliding filament mechanism of muscle contraction
- initiated by the release of calcium ions from the sarcoplasmic reticulum and the binding of those ions to the troponin molecule on the thin filament
- this results in a change in shape of the troponin which moves the tropomyosin molecule and exposes the binding sites on the actin filament for the myosin heads
- contraction results as the myosin heads of the thick filaments attach to the thin filaments at both ends of the sarcomere and pull the the thin filaments towards the center of the sarcomere by pivoting inward
- after the myosin head pivots at its “hinge” it lets go, returns to original position, binds to the thin filament farther along its length and pivots again
what is concentric contraction?
a muscle generates force while shortening
- sliding filament mechanism
1) myosin heads attach to the actin in the thin filament, then pivot to pull the thin filaments towards the M line
2) freeze fracture TEM through the A band of a sarcomere showing myosin heads attached to the thin filaments
what is eccentric contraction?
a muscle generates force while lengthening
- essential for controlled movement and resistance to gravity
how does the length of a muscle fiber (how stretched or contracted it is at a given moment) impact the force it can generate?
the optimal length occurs when a fiber is slightly stretched so that its thin and thick filaments over-lap only to a moderate extent
- if a muscle fibers are stretched too much that the thick and thin filaments do not overlap at all then the myosin heads have nothing to attach to and no pulling force can be generated
- the sites of muscle attachments tend to keep muscles within the optimal range that joints normally do not let any bone move so widely that its attached muscles could shorten or stretch beyond their range
what are the 3 types of muscle fibers?
slow oxidative
fast glycolytic
fast oxidative
describe slow oxidative fibers
- obtain their energy from aerobic metabolic reactions and have a large number of mitochondria and rich supply of capillaries
- thin and red (abundance of myoglobin
- contract slowly
-resistant to fatigue as long as enough oxygen is present - prolonged contractions
- do not generate much power
describe fast glycolytic fibers?
- pale (contain little myoglobin)
- twice as thick as slow oxidative, contain more myofilaments, and generate more power
- depend on anaerobic pathways to make ATP, contain few mitochondria and capillaries
- glycosomes as fuel source
- muscles of upper limbs
describe fast oxidative fibers?
- contract quickly
- oxygen dependent
- high myoglobin content
- large number of mitochondria
- large supply of capillaries
- aerobic metabolism
- fatigue resistant but less so than SO
- intermediate speed of contraction
- lower limbs
how does the arrangement of fascicles in muscle impact range of motion (how far the muscle will move something when contracted) vs force generation?
- the more parallel the fibers are the more the muscle can shorten resulting in a larger range of motion, but do not have large force generation
- power of muscle depends more on total fibers it contains
describe a first class lever
fulcrum is located between the load and the point at which the effort is applied (see saws)
- can operate at either mechanical advantage (for power) or mechanical disadvnatage (speed and distance) depending on lengths of the load
describe a second class lever
the load and the effort are on the same side of the fulcrum
- effort is applied farther away from the fulcrum than the load (wheelbarrow)
- effort is longer than the load
- mechanical advantage (power)
- standing on ur toes
describe a third class lever
effort is applied closer to the fulcrum than the load
- load is longer than the effort
- mechanical disadvantage (speed and distance)
- flexion of the forearm by the biceps
- positioning of muscle insertions close to the joint, providing stability for fast movements like running