Exam 3 Flashcards
a set of immune cells present in many tissues that capture antigens & present them to T cells
Dendritic Cells
receptors on certain types of animal cells that bind pathogen-associated molecular patterns (PAMPs)
Pattern Recognition Receptors
a type of white blood cell whose cytoplasmic granules absorb acidic stains
Eosinophil
an organism, usually a microorganism, capable of producing disease
Pathogen
serious condition in which Rh+ red blood cells (which bear antigen D) of a fetus are destroyed by material anti-D antibodies
Erythroblastosis
mechanisms of communication between cells
Cell Signaling
a type of specific immune response carried out by T cells
Cell-Mediated Immunity
the increase in number of T cells or B cells specific for an antigen
Clonal Expansion
an acute allergic reaction following sensitization to a foreign substance or other substance
Anaphylaxis
identical antibody molecules produced by cells cloned from a single cell
Monoclonal Antibodies
a large granular lymphocyte that functions in both nonspecific & specific immune responses
Natural Killer Cell (NK Cell)
the retrovirus that causes AIDS
Human Immunodeficiency Virus (HIV)
a type of granular leukocyte important in immune responses
Neutrophil
temporary immunity that depends on the presence of immunoglobulins produced by another organism
Passive Immunity
a group of proteins in blood & other body fluids that are activated y an antigen-antibody complex & then destroy pathogens
Complement
the combination of antigen & antibody molecules
Antigen-Antibody Complex
mechanisms such as physical barriers (e.g., the skin) & phagocytosis that provide immediate & general protection against pathogens
Nonspecific Immune Responses
a commercially produced, weakened or killed antigen associated with a particular disease that stimulates the body to make antibodies
Vaccine
the response of body tissues to injury or infection, characterized clinically by heat, swelling, redness, & pain, & physiologically by increased dilation of blood vessels & increased phagocytosis
Inflammatory Response
literally, “cell eating”; a type of endocytosis by which certain cells engulf food particles, microorganisms, foreign matter, or other cells
Phagocytosis
cell that secretes antibodies; a differentiated B lymphocyte
Plasma Cell
red blood cell antigens, known as D antigens, 1st identified in Rhesus monkeys
Rh Factors
the rapid production of antibodies induced by a second exposure to an antigen several days, weeks, or even months after the initial exposure
Secondary Immune Response
a cell that displays foreign antigens as well as its own surface proteins
Antigen-Presenting Cell (APC)
substance released from mast cells that is involved in allergic & inflammatory reactions
Histamine
process of recognizing foreign macromolecules & mounting a response aimed eliminating them
Immune Response
the response of the immune system to 1st exposure to an antigen
Primary Immune Response
cytokines that kill tumor cells & stimulate immune cells to initiate an inflammatory response
Tumor Necrosis Factors (TNFs)
a substance that stimulates an allergic reaction
Allergen
cytokines produced by animal cells when challenged by a virus
Interferons
an endocrine gland that functions as part of the lymphatic system; processes T cells
Thymus Gland
immunity that develops as a result of exposure to antigens; it can occur naturally after recovery from a disease or can be artificially induced by immunization a vaccine
Active Immunity
a hypersensitivity to some substance in the environment, manifested as hay fever, skin rash, asthma, food allergies, etc.
Allergy
B or T cell (lymphocyte) that permits rapid mobilization of immune response on 2nd or subsequent exposure to a particular antigen
Memory Cell
T lymphocyte that suppresses the immune response
Suppressor T Cell
soluble molecules that destroy pathogens
Antimicrobial Peptides
a serious, potentially fatal disease caused by the human immunodeficiency virus (HIV)
Acquired Immunodeficiency Syndrome (AIDS)
programmed cell death
Apoptosis
a disease in which the body producers antibodies against its own cells or tissues
Autoimmune Disease
the type of white blood cell responsible for antibody-mediated immunity
B Cell (B Lymphocyte)
defense mechanisms that target specific macromolecules associated with a pathogen
Specific Immune Responses
a type of cell found in connective tissue
Mast Cell
an abdominal organ located just below the diaphragm that removes worn-out blood cells & bacteria from the blood & plays a role in immunity
Spleen
a specific protein (immunoglobulin) that recognizes & binds to specific antigens; produced by plasma cells
Antibody
a type of specific immune response in which B cells differentiate into plasma cells & produce antibodies that bind with foreign antigens, leading to the destruction of pathogens
Antibody-Mediated Immunity
any molecule, usually a protein or large carbohydrate, that is specifically recognized as foreign by cells of the immune system
Antigen
distinctive molecules on bacteria & other pathogens that are not found in animals
Pathogen-Associated Molecular Patterns
a diverse group of cytokines produced mainly by macrophages & lymphocytes
Interleukins
white blood cell with nongranular cytoplasm that governs immune responses
Lymphocyte
an enzyme found in many tissues & in tears & other body fluids
Lysozyme
a group of membrane proteins, present on the surface of most cells, that are slightly different in each indivdual
Major Histocompatibility Complex (MHC)
a large phagocytic cell capable of ingesting & digesting bacteria & cell debris
Macrophage
signaling proteins that regulate interactions between cells in the immune system
Cytokines
a rapid, widespread allergic reaction that can lead to death
Systemic Anaphylaxis
a type of white blood cell responsible for a wide variety of immune functions, particularly cell-mediated immunity
T Cell (T Lymphocyte)
T lymphocyte that destroys cancer cells & other pathogenic cells on contact
T Cytotoxic Cell (TC)
T lymphocyte that activates B cells (B lymphocytes) & stimulates T cytotoxic cell production
T Helper Cell (TH)
lymphocyte activation in which a specific antigen causes activation, cell division, & differentiation only in cells that express receptors with which the antigen binds
Clonal Selection
a type of pattern recognition receptor. Cell-surface receptors on several cell types that recognize pathogen-associated molecular patterns
Toll-Like Receptors
an immune response directed against a transplanted tissue or organ
Graft Rejection