Exam 2: Virology Flashcards

1
Q

Neurotropic viruses in dogs include

A

Rabies, Canine Distemper Virus, Canine Herpes Virus

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2
Q

Of the neurotropic viruses in horses, which one is rarely neurotropic?

A

Equine infectious anemia viruses

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3
Q

What viral family does Canine Distemper belong to?

A

Paramyxovirus

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4
Q

What are the different cell types that can be infected by canine distemper virus?

A

Epithelial, lymphoid, astrocytes and oligodendroglial

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5
Q

What systems of the body does canine distemper virus affects?

A

the skin, respiratory tract, GIT, brain and urinary tract

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6
Q

Infection from Canine Distemper Virus can produce both intracytoplasmic and intranuclear inclusion bodies. When does infection occur?

A

Between 3-6 months of age after the maternal antibodies start decreasing

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7
Q

The pathogenesis of ________ virus is this:
Infection -> CNS (transported by lymphocytes, monocytes and platelets -> virus spreads in CSF leading to inflammatory and demyelinating lesions.

A

Canine Distemper Virus

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8
Q

(T/F) Canine distemper produces intracytoplasmic inclusion bodies only.

A

F, produces both intracttoplasmic and intranuclear inclusion bodies

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9
Q

By what cells is canine distemper virus carried to the CNS?

A

Lymphocytes, monocytes, and platelets

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10
Q

Name the clinical signs associated with canine distemper virus infections

A

Leukopenia, vomiting, diarrhea, conjunctivitis, nasal discharge, coughing, hardening of nose and footpads

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11
Q

What may the demyelination progress to in canine distemper virus?

A

Necrosis and infiltration by gitter cells

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12
Q

True or false: diagnosis of canine distemper virus is by PCR or virus isolation

A

True

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13
Q

What viral family does the rabies virus belong to?

A

Rhabdovirus

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14
Q

True or false: rabies virus infects the cardiovascular system of all mammals, including humans

A

False, rabies infects the nervous system

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15
Q

What type of rabies is maintained in raccoons, skunks, bats, and foxes?

A

Sylvatic rabies

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16
Q

How is rabies transmitted?

A

Through contact with saliva from an infected animal

17
Q

When is rabies diagnosed?

A

Post-mortem