Exam 2 - Topic 2 - Homeostasis Flashcards

1
Q

Homeostasis

A
  • maintenance of nearly constant conditions in the internal Enviornment
  • what a perfusionist does
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2
Q

Molecules that easily diffuse

A
  • H2O
  • O2
  • CO2
  • N
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3
Q

Molecules that do not easily diffuse

A
  • Large molecules
  • Proteins
  • charged/polar molecules
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4
Q

Relative protein [ ]’s

A
  • Highest in cell - then blood - then ECF
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5
Q

How body controls blood flow across organ systems?

A
  • Since pressure remains constant….resistance is changed by body to alter flow
  • constrict / dilate arterioles and other vessels
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6
Q

Body water

A
  • 60% of body weight
  • Intracellular compartment
    - hold 2/3 of water / includes volume in all RBC
  • Extracellular compartment
    - This is the internal environment
    - Interstitial / plasma / transcellular
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7
Q

ECF

A
  • Extracellular fluid
  • function is transportation
  • contains:
    Ions / amino acids / fats / O2 / glucose
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8
Q

Location of cells relative to capillaries

A
  • Very close

- Almost all cells

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9
Q

Body water compartment %’s

A

Intracellular
- 40% body weight
- 67% body water
Extracellular
- 20% body weight (4 in plasma - 16 in interstitial)
- 33% body water (7 in plasma - 26 in interstitial)

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10
Q

Ion [ ] ‘s in compartments (outside and inside cell)

A
Na: 142 out / 10 inside
K:    4 out    / 140 inside
Ca: 2.4 out / 0.0001 inside
Mg: 1.2 out / 58 inside
Cl:  103 out / 4 inside
- All in mEq/L
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11
Q

Origin of nutrients

A
  • Respiratory: O2
  • GI System: Carbs, fats, amino acids
  • Liver/fat cells/GI mucosa/kidneys/endocrine:
    Transform substances into usable form
    Store substances for later use
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12
Q

Removal of metabolic end products

A
  • Respiratory: CO2
  • Renal system: urea / excess ions / excess water
  • GI tract: undirected material
  • Liver: toxic substances / other waster products
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13
Q

Distribution of blood flow

A
Heart - 3%
Brain - 14%
Muscle - 15%
Bone - 5%
Liver - 27% (6% from arterial / 21% from GI portal)
Kidney - 22%
Skin - 6%
Bronchi - 2%
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