Exam 2 - Study Material Flashcards
What is anxiety?
- A diffuse apprehension that is vague in nature and associated with feelings of uncertainty and helplessness
- It is provoked by the unknown and precedes all new experiences
What are some characteristics of anxiety?
- Anxiety is an emotion without a specific object
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Anxiety is communicated interpersonally
- Anxiety can be transmitted from person to person
- Necessary for survival
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The crux of anxiety is self-preservation
- Anxiety occurs as a result of a threat to a person’s selfhood, self-esteem, or identity
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- Anxiety occurs as a result of a threat to a person’s selfhood, self-esteem, or identity
How is culture related to anxiety?
- Culture can influence the values one considers most important
- Underlying every fear is the anxiety of losing one’s own being
- A person can grow from the anxiety to the extent that the person confronts, moves through, and overcomes anxiety-creating experiences
What is fear?
- cognitive appraisal of threatening stimulus
- Fear has a specific source or object that the person can identify and describe
- Fear involves the intellectual appraisal of a threatening stimulus
- Anxiety is the emotional response to that appraisal
- Fear produces anxiety
What are the different levels of anxiety?
- Mild
- Moderate
- Severe
- Panic
Describe mild anxiety
- Associated with the tension of day-to-day living
- During this stage the person is alert and the perceptual field is increased.
- The person sees, hears, and grasps more than before.
- This kind of anxiety can motivate learning and produce growth and creativity
Describe moderate anxiety
- The person focuses only on immediate concerns, involves the narrowing of the perceptual field.
- The person sees, hears, and grasps less.
- The person blocks selected areas but can attend to more if directed to do so.
Describe severe anxiety
- Marked by a significant reduction in the perceptual field.
- The person tends to focus on a specific detail and not think about anything else.
- All behavior is aimed at relieving anxiety, and much direction is needed to focus on another area
Describe panic
- Associated with awe, dread, and terror, and the person feeling it is unable to do things even with direction.
- Involves the disorganization of the personality and can be life threatening.
- Increased motor activity, decreased ability to relate to others, distorted perceptions, and loss of rational thought. Unable to communicate or function effectively
- Prolonged period of panic would result in exhaustion and death
What is biofeedback?
The use of a machine to reduce anxiety and modify behavioral responses. Small electrodes are connected to the biofeedback equipment which are attached to the patient’s forehead to measure vital signs
What are ego defense mechanisms?
- First line of psychic defense
- Use to cope successfully with mild and moderate levels of anxiety
- Protects from feelings of inadequacy and worthlessness
- Prevents awareness of anxiety
- Extreme use distorts reality, interferes with interpersonal relationships, limits ability to work
What are some Ego defense mechanisms?
- Compensation
- Denial
- Displacement
- Dissociation
- Identification
- Intellectualization
- Introjection
- Projection
- Reaction formation
- Repression
- Sublimation
- Undoing
- Isolation
- Rationalization
- Regression
- Splitting
- Suppression
What is the “Compensation” defense mechanism? Give an example
Process by which people make up for a perceived weakness by strongly emphasizing a feature they consider more desirable
- EX: A businessman perceives his small physical stature negatively. He tries to overcome this by being aggressive, forceful, and controlling in business dealings
What is the “denial” defense mechanism? Give an example
Avoidance of disagreeable realities by ignoring or refusing to recognize them; the simplest and most primitive of all defense mechanisms
- EX: Ms. P has just been told that her breast biopsy indicates a malignancy. When her husband visits her that evening, she tells him that no one has discussed the laboratory findings with her
What is the “displacement” defense mechanism? Give an example
Shift of emotion from a person or object to another, usually neutral or less dangerous, person or object
- EX: A 4-year-old boy is angry because he has just been punished by his mother for drawing on his bedroom walls. He begins to play war with his soldier toys and has them fight with each other
What is the “dissociation” defense mechanism? Give an example
The separation of a group of mental or behavioral processes from the rest of the person’s consciousness or identity
- EX: A man is brought to the emergency room by the police and is unable to explain who he is and where he lives or works
What is the “identification” defense mechanism? Give an example
Process by which people try to become like someone they admire by taking on thoughts, mannerisms, or tastes of that person
- EX: Sally, 15 years old, has her hair styled like that of her young English teacher, whom she admires
What is the “intellectualization” defense mechanism? Give an example
Excessive reasoning or logic is used to avoid experiencing disturbed feelings
- EX: A woman avoids dealing with her anxiety in shopping malls by explaining that shopping is a frivolous waste of time and money
What is the “Introjection” defense mechanism? Give an example
Intense identification in which people incorporate qualities or values of another person or group into their own ego structure. It is one of the earliest mechanisms of the child, important in formation of conscience
- EX: Eight-year-old Jimmy tells his three-year-old sister, “Don’t scribble in your book of nursery rhymes. Just look at the pretty pictures,” thus expressing his parent’s values
What is the “Isolation” defense mechanism? Give an example
Splitting off of emotional components of a thought, which may be temporary or long term
- A medical student dissects a cadaver for her anatomy course without being disturbed by thoughts of death
What is the “projection” defense mechanism? Give an example
Attributing one’s thoughts or impulses to another person. Through this process one can attribute intolerable wishes, emotional feelings, or motivation to another person
- EX: A young woman who denies she has sexual feelings about a co-worker accuses him without basis of trying to seduce her
What is the “rationalization” defense mechanism? Give an example
Offering a socially acceptable or apparently logical explanation to justify or make acceptable otherwise unacceptable impulses, feelings, behaviors, and motives
- EX: John fails an examination and complains that the lectures were not well organized or clearly presented
What is the “reaction formation” defense mechanism? Give an example
Development of conscious attitudes and behavior patterns that are opposite to what one really feels or would like to do
- EX: A married woman who feels attracted to one of her husband’s friends treats him rudely
What is the “regression” defense mechanism? Give an example
Retreat to behavior characteristic of an earlier level of development
- EX: Four-year-old Nicole, who has been toilet trained for more than 1 year, begins to wet her pants again when her new baby brother is brought home from the hospital
What is the “repression” defense mechanism? Give an example
Involuntary exclusion of a painful or conflicted thought, impulse, or memory from awareness. It is the primary ego defense, and other mechanisms tend to reinforce it
- EX: Mr. R does not recall hitting his wife when she is pregnant
What is the “splitting” defense mechanism? Give an example
Viewing people and situations as either all good or all bad; failure to integrate the positive and negative qualities of oneself
- EX: A friend tells you that you are the most wonderful person in the world one day and how much she hates you the next day
What is the “sublimation” defense mechanism? Give an example
Acceptance of a socially approved substitute goal for a drive whose normal channel of expression is blocked
- EX: Ed has an impulsive and physically aggressive nature. He tries out for the football team and becomes a star tackle
What is the “suppression” defense mechanism? Give an example
A process often listed as a defense mechanism, but really it is a conscious counterpart of repression. It is intentional exclusion of material from consciousness. At times, it may lead to repression
- EX: A young man at work finds he is thinking so much about his date that evening that it is interfering with his work. He decides to put it out of his mind until he leaves the office for the day
What is the “undoing” defense mechanism? Give an example
Act or communication that partially negates a previous one; a primate defense mechanism
- EX: Larry makes a passionate declaration of love to Sue on a date. At their next meeting he treats her formally and distantly
What are some familial factors that can contribute to anxiety?
o Anxiety disorders run in families & are common
o 40% heritability
o Family Hx of a psych. Illness are 3x more likely to develop Post-Traumatic Stress disorder following a traumatic event
o No single or specific gene identified – b/c of the critical role that environment plays in modulating genetic susceptibility in mental disorder
o Anxiety disorder overlap – ex. Anxiety & depression
What are some psychological factors that can contribute to anxiety?
Parents play a huge role in how children will develop based on their reactions
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Self-esteem-
- People who are easily threatened or has a low level of self-esteem are more likely to develop anxiety
- Anxiety is caused by perception of ability or self-concept
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Resilience-
- Associated with a number of protective psychosocial factors, including active coping style, positive outlook, interpersonal relatedness, moral compass, social support, role models, and cognitive flexibility
- Those that are able to deal with major stressors at a young age will likely be able to deal with stressors at adulthood
- Uncontrolled stress during childhood may make the adult more vulnerable to future stressors
What are some neurotransmitters that affect anxiety?
GABA system
- regulator of anxiety; controls anxiety or firing rates of neurons in parts of the brain that are responsible for producing anxiety (limbic system)
- most common inhibitory neurotransmitter
- when it crosses the synapse & binds to the GABA receptors à channels open à exchange of ions à exchange inhibits / reduces cell excitability à slows cell activity
- Clinical result: person becomes less anxious
Norepinephrine system
- mediates flight or flight
- Anxiety is caused by the inappropriate activation of the NE in the locus ceruleus
- Imbalance btw NE & other neurotransmitters
Serotonin system
- pts experiencing anxiety d/o can have hypersensitive 5-HT receptors
- SSRIs effectively treat anxiety!!
What are the different types of anxiety disorders?
- Separation anxiety disorder
- Selective mutism
- Specific phobia
- Social anxiety disorder (social phobia)
- Panic disorder
- Agoraphobia
- Generalized anxiety disorder
What are some characteristics of Separation Anxiety Disorder?
- Associated with times of transition
- May present with sudden fear or discomfort with somatic symptoms
- Fearful of accidents befalling the parent
- Often lack insight about feeling anxious
What are some nursing interentions for Separation Anxiety Disorder?
- Through assessment of child/adolescent (e.g. occurrence of recent, traumatic event)
- Collection of data related to home and/or school environment (e.g. presence of bullying behavior at school)
What is the criteria to be diagnosed with Selective Mutism?
- Consistent failure to speak in specific social situations (e.g., at school) despite speaking in other situations
- Disturbance interferes with other achievements
- Failure to speak not attributable to lack of knowledge of, or comfort with language; occurrence: rare
What is the criteria to be diagnosed with specific phobia?
- Marked fear/anxiety about a specific object or situation (e.g., flying, animals, heights, receiving an injection, seeing blood, etc.)
- The fear/anxiety is out of proportion to the actual danger posed by object/situation
What are some nursing nursing interventions for specific phobia?
- Support & reassurance
- Progressive relaxation techniques
- Systematic desensitization approaches
- The treatment of choice for specific phobias is exposure-based procedures, particularly in vivo exposure.
- In general, pharmacological treatments have not proved effective for specific phobias
What are some treatments for specific phobias?
- The treatment of choice for specific phobias is exposure-based procedures, particularly in vivo exposure.
- In general, pharmacological treatments have not proved effective for specific phobias
What is the criteria to be diagnosed with social anxiety disorder (social phobia)?
- Marked fear/anxiety about 1 or more social situations in which the individual is exposed to possible scrutiny by others
- The fear/anxiety is out of proportion to the actual event.
- Individual has intense fears of being negatively evaluated, humiliated, embarrassed, or rejected
- Leads to social withdrawal in some individuals
What are some treatments for social anxiety disorder?
- The most common treatment approaches to social phobia include social skills training, relaxation techniques, exposure-based methods, and multicomponent cognitive behavioral treatments, with the latter two attaining the highest levels of treatment efficacy
- SSRIs are an attractive first-line treatment for social phobia
What are some nursing interventions for social anxiety disorder?
- Cognitive restructuring
- Learning to monitor thoughts & feelings
- Reframing situations
- Learning new behaviors
- Role playing
- Social skills training
- Encourage patient to express thoughts & feelings.
- Assist patient to distinguish between actual phobic trigger & problems related to avoidance behavior.
- Teach patient & family about phobic reactions when necessary.
What is the criteria to be diagnosed with panic disorder?
Recurrent unexpected panic attacks, which involve abrupt surges of intense fear/discomfort that reach a peak within minutes & involve:
- Palpitations, pounding heart, or tachycardia
- Sweating
- Trembling or shaking
- Shortness of breath or smothering sensation
- Feelings of choking
- Chest pain or discomfort
- Nausea or abdominal distress
- Feeling dizzy, unsteady, light-headed, or faint
- Chills or hot flushes
- Paresthesias (numbness or tingling)
- Derealization (feelings of unreality)
- Depersonalization (being detached from oneself)
- Fear of losing control or “going crazy”
- Fear of dying
What are some nursing interventions for panic disorder?
- Stay with patient & acknowledge discomfort
- Use short, simple, and clear statements, give directions one at a time, give brown bag for hyperventilation
- Remain calm in your approach
- DO NOT ASK “WHY” QUESTIONS TO THE PATIENT
- Decrease external stimuli
- Protect the patient
- Be aware of own feelings
- Administration of anxiolytic when indicated
What are some treatments for panic disorder?
- Cognitive behavioral treatments are effective for persons with panic disorder with no more than mild agoraphobia. These treatments focus on cognitive therapy, exposure to interoceptive sensations similar to physiological panic sensations, and breathing
- SSRIs are now considered to be the first-line pharmacological treatment for PD, affecting panic frequency, generalized anxiety, disability, and phobic avoidance
What is Agoraphobia?
fear of open spaces
What is the criteria to be diagnosed with Agoraphobia?
- Marked fear/anxiety about 2 (or more) of the following:
- Using public transportation
- Being in open spaces
- Being in enclosed places
- Standing in line or being in a crowd
- Being outside of the home alone
What are some nursing interventions for Agoraphobia?
- Accept patients and their fears with a non-critical attitude
- Ivolve patients in activities that do not increase anxiety
- Involve patients in activities that will increase involvement rather than avoidance
What is the criteria to be diagnosed with generalized anxiety disorder?
- Excessive anxiety & worry that is hard to control, occurs most days, & has been present for the past 6 months
Associated with 3 or more of the following:
- Restlessness, feeling keyed up or on edge
- Easily fatigued
- Difficulty concentrating; mind going blank
- Irritability
- Muscle tension
- Sleep disturbance (difficulty falling or staying asleep, or restless, unsatisfying sleep)
What are some nursing interventions for generalized anxiety disorder?
- Teaching relaxation techniques
- Exercise
- Cognitively-oriented therapy
- Move pt. to calm quiet envi, ask pt to identify how they feel, encourage pt. to describe/discuss feelings, help pt. identify possible causes of feelings
- Listen to pt. expression of hopelessness/helplessness, ask pt if they feel suicidal
What are the treatments for generalized anxiety disorder?
- The pharmacological treatments of choice are buspirone and antidepressants, including SSRIs and venlafaxine
- The most successful psychological treatments for GAD combine relaxation, exercise, and cognitive therapy with the goal of bringing the worry process under the patient’s control
What are some treatments for obsessive-compulsive disorder (OCD)?
- Cognitive behavioral therapy involving exposure and ritual prevention is a well-established treatment for OCD in adults.
- SSRIs have been shown repeatedly to be efficacious in the treatment of OCD.
- Behavior therapy and perhaps cognitive therapy may be superior to medication with respect to risks, costs, and enduring benefit
What is the difference between anxiety and depression?
Anxiety:
- Predominantly fearful or apprehensive
- Difficulty falling asleep (initial insomnia
- Depersonalization (feeling detached from one’s body)
- Derealization (feeling that one’s environment is strange, unreal, or unfamiliar
- Selective and specific negative appraisals that do not include all areas of life
- Sees some prospects for the future
- Does not regard defects or mistakes as irrevocable
Depression:
- Depersonalization (feeling detached from one’s body)
- Derealization (feeling that one’s environment is strange, unreal, or unfamiliar
- Inability to experience pleasure
- Loss of interest in usual activities
- Selective and specific negative appraisals that do not include all areas of life
- Thoughts of death or suicide Sees the future as bleak and has given up all hope
- Regards mistakes as beyond redemption
What is obsessive-compulsive disorder?
Involves presence of obsessions, compulsions, or both:
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Obsessions – recurrent persistent thoughts, urges, or images that are experienced, at some time during the disturbance, as intrusive & unwanted, and that in most individuals cause marked anxiety or distress
- Individual attempts to ignore or suppress such thoughts, urges, or images, or to neutralize them with some other thought or action (i.e. by performing a compulsion)
- EX: Fear of dirt and germs or Fear of burglary or robbery
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Compulsions – repetitive behaviors (e.g. hand washing, ordering, checking) or mental acts (e.g. praying, counting, repeating words silently) that the individual feels driven to perform in response to an obsession or according to rules that must be applied rigidly
- Aimed at preventing or reducing anxiety or distress, or preventing some dreaded situation
- EX: Excessive hand washing or Repeated checking of door and window locks
What impact does OCD have on patients?
- Time-consuming
- Cause clinically significant distress or impairment
- Negatively affect quality of life
- Not attributable to the physiological effects of a substance or another medical condition
- Not better explained by another medical disorder
What are the treatment options for a patient with OCD?
Psychotherapy
- Cognitive behavioral therapy
Medications (antidepressants)
- Clomipramine (Anafranil)
- Fluvoxamine (Luvox)
IF medications and psychotherapy are not effective enough in controlling OCD symptoms of some individuals. In rare cases, other treatment options may include:
- Psychiatric hospitalization
- Residential treatment
- Electroconvulsive therapy (ECT)
- Transcranial magnetic stimulation
- Deep brain stimulation
What are some nursing interventions for patients with OCD?
- Ensure that basic needs are met.
- Provide patients with time to perform rituals (unless they are in specialized OCD program, such as ERP).
- Discuss program expectations, routines, and goals.
- Be empathic toward patients and aware of their need to perform compulsions (rituals).
- Assist patients with connecting behaviors with thoughts and feelings
- Structure simple tasks, activities, or games for patients.
- Reinforce positive non-ritualistic behaviors.
What is the criteria to be diagnosed with body dysmorphic disorder (BDD)?
- Preoccupation with one or more perceived defects or flaws in physical appearance that are not observable or appear slight to others
- Repetitive behaviors (e.g., mirror checking, excessive grooming, skin picking, reassurance seeking) or mental acts (e.g., comparing his/her appearance with that of others) in response to the appearance concerns
- Results in significant distress and/or impairment in functioning
What are the characteristics of body dysmorphic disorder (BDD)?
- Usually begins during adolescence & can occur in childhood.
- Appears to occur about equally in males & females
- Major depression—most common comorbid disorder
- May be difficult to diagnose, as many patients are too ashamed to reveal their symptoms.
- Possibility of BDD should be explored when patients are:
- Housebound,
- Have unnecessary surgery or dermatologic treatment
- Have social anxiety, depression, or suicidal ideation.
What are the treatment options for patients with body dysmorphic disorder?
Medications
- SSRIs—may require higher doses than for depression
Psychotherapy
- Cognitive behavioral therapy
Psychoeducation:
- For patient & family
What is Obsessive-Compulsive Personality Disorder?
- Extremely rigid and controlling
- Perfectionistic
- Overly organized
- Pays extreme attention to detail in an exaggerated manner
- No obsessive compulsions
What is the criteria to be diagnosed with a hoarding disorder?
- Persistent difficulty discarding or parting with possessions, regardless of their actual value
- Results in accumulation of possessions that congest & clutter active living areas
- Compromises having safe environment for self & others
- Hoarding not attributable to another medical condition
- Does excessive acquisition of items occur?
- (Occurs in 80-90% of cases)
- Insight may be in the “good to delusional” range.
- Nationally representative prevalence studies of this disorder not available.
What are some treatment options for patients with hoarding disorders?
Challenging: Many “hoarders” lack insight & do not see their behavior as a problem
Options:
- Medications—SSRIs
- Might use CCB’s + SSRI’s to treat this – they help with the obsessiveness of keeping all of that stuff
- Cognitive behavioral therapy
What is the criteria to be diagnosed with trichotillomania?
- Recurrent pulling out of one’s hair, resulting in hair loss
- Repeated attempts to decrease of stop hair pulling
- Behavior causes significant distress or impairment
- Not attributable to another medical condition
- Not better explained by symptoms of another mental disorder
What are the symptoms associated with trichotillomania?
- Symptoms usually seen in children:
- Uneven appearance to the hair
- Bare patches or diffuse loss of hair
- Bowel obstruction if individuals eat the hair they pull out
- Frequent tugging, pulling, or twisting the hair
- Denying the hair pulling
- Hair regrowth that feels like stubble in the bare spots
- Increasing sense of tension before the hair pulling
- Other self-injury behaviors
- Sense of relief, pleasure, or gratification after the hair pulling
What are the treatment options for patients with trichotillomania?
Medications:
- Naltrexone (ReVia) & SSRIs effective in reducing some symptoms
Psychotherapy:
- Behavioral therapy (e.g., habit reversal training)
What is posttraumatic stress disorder and what are the symptoms?
Essential feature — development of characteristic symptoms following exposure to one or more traumatic events
Symptoms may be:
1) Fear-based emotional re-experiencing of event
2) Anhedonic or dysphoric mood states
3) Arousal & reactive responses
4) Dissociative states
5) Combinations of the above symptoms
What is the criteria to be diagnosed with PTSD?
Exposure to actual or threatened death, serious injury, or sexual violence
- Directly experiencing the event
- Witnessing, in person the event as it occurred to others
- Learning that event (violent or accidental)
- occurred to close family member/friend
- Experiencing repeated or extreme exposure to aversive details of traumatic event
Presence of one (or more) intrusion symptoms, beginning after traumatic event, such as:
- Recurrent , involuntary, & intrusive distressing memories of traumatic event
- Recurrent distressing dreams in which the content and/or affect of dream are related to traumatic event
- Dissociative reactions (e.g., flashbacks) in which individual feels as if event were still occurring
Negative alterations in cognitions & mood associated with the traumatic event(s) beginning or worsening after the traumatic event occurred, as evidenced by:
- Inability to remember an important aspect of the traumatic event (usually due to dissociative amnesia)
- Persistent & exaggerated negative beliefs or expectations about oneself, others, or the world
Marked alterations in arousal & reactivity associated with traumatic event(s) occurred, as evidenced by:
- Irritable behavior & angry outbursts (with little or no provocation) typically expressed as verbal or physical aggression toward people or objects
- Reckless or self-destructive behavior
- Hypervigilance & exaggerated startle response
Sometimes accompanied by dissociative symptoms such as depersonalization & derealization
To use this subtype, the dissociative symptoms must not be attributable to the physiological effects of a substance
What are some interventions for patients with PTSD?
- Approach the individual in a professional, nonthreatening manner; avoid startling patients with PTSD.
- Encourage expression of feelings in a safe environment.
- Encourage patient to identify & contact supportive resources in the community or on the internet.
- Encourage use of stress management & relaxation techniques.
What are some treatment options for patients with PTSD?
Medications:
- SSRIs (best side effect profile)
- TCAs
- MAOIs
P_sychosocial treatments_:
- Past-focused: repeated exposure to memories & emotions of traumatic events to neutralize their impact
- Present-focused: teaching coping skills
How are Benzodiazepines used to treat anxiety?
- The BZs are thought to reduce anxiety because they are powerful receptor agonists of the inhibitory neurotrans- mitter GABA
- The BZ molecule and GABA bind to each other at the GABA receptor site. The result is an enhancement of the actions of GABA, resulting in an inhibition of neurotransmission (a decrease in the firing rate of neurons) and thus a clinical decrease in the person’s level of anxiety.
What is a nonbenzodiazepine medication and how is it used for anxiety?
- Buspirone (Buspar), a non-BZ anxiolytic drug, is a potent antianxi- ety agent with no addictive potential and has FDA approval for the treatment of GAD.
- It is most effective in patients who have never taken BZs and therefore are not expecting immediate effects from drug treatment.
What are some Nonbenzodiazepine sedative-hypnotic agents and what are some characteristics of these drugs?
- Zolpidem, zaleplon, and eszopiclone are a new class of com- pounds for treatment of insomnia.
- Are well tolerated and have few antianxiety, anticonvulsant, or muscle-relaxant properties.
- Side effects include daytime drowsiness, dizziness, and gastrointestinal upset.
- The pri- mary difference among these drugs is their half-life and sub- sequent length of action.
- All three drugs are Schedule IV controlled substances.
Why do people use drugs?
- They make us feel good.
- Relaxation
- Euphoria
- Stimulation of senses
- Altered awareness
What is substance withdrawl?
Symptoms that result from a biological need that develops when the body becomes adapted to having the drug in the system.
What is substance dependence?
Indicates a severe condition, usually considered a disease. There may be physical problems and serious disruptions in the person’s work, family, and social life.
What is a dual diagnosis?
It is the co-existence of substance abuse and one or more psychiatric disorders in the same person
What is tolerance?
Describes an increased need of a substance to produce the same effect that a lower dose once produced.
What is codependence?
Reffers to people who had problems as a result of living in a committed relationship with a person with alcoholism (or another drug abuse problem)
Describe substance abuse related disorders in nurses
Nurses are at high risk for substance use problems due to high job stress and access to drugs. As it is in the general population, alcohol is the drug of choice for nurses, and nurses’ choice of substance is influenced by availability and exposure. Of all health care professionals, physicians and nurses use parenteral narcotics the most in their practices, and they are more likely to choose these drugs for their own use. Among narcotics, the drug of choice for nurses is meperidine (Demerol).