Exam 2 Quiz 6 Flashcards
Considers the interactions
that take place between the biomaterial and the host environment.
Biocompatibility
Is a biomaterial a property or an event?
An event/interaction
Biological performance in a specific application that is judged suitable for that site/situation.
Biocompatible
Founder of biomaterials
Jonathon Black
The two main considerations of Biological Performance
Host Response and Materials Response
Host Response
One of the main factors of Biological Performance; Local or systemic response other than the intended therapeutic response of the living system
Materials Response
One of the main factors of Biological Performance; the response of the material to the living system
Can a material by itself be biocompatible?
NO, size, shape, etc. all matter
A material that elicits a reproducible, quantifiable host response in a standard test.
Reference (control) material-can be (-) and elicit no/minimal response or +
A well defined, repeatable test
Standard test
Requirements for a material to be biocompatible
Non-Toxic Biochem compatible Non-irritable Non-Carcinogenic Non-immunogenic Bio Adhesive
Neutrophils ultimately mean
Toxicity
move things
Phagocytes
three biological rxns to biomaerials
Toxicity, inflammation, and mutagens
particulate debris
incompatible, no matter the material