Exam 2 Quiz 6 Flashcards

1
Q

Considers the interactions

that take place between the biomaterial and the host environment.

A

Biocompatibility

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2
Q

Is a biomaterial a property or an event?

A

An event/interaction

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3
Q

Biological performance in a specific application that is judged suitable for that site/situation.

A

Biocompatible

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4
Q

Founder of biomaterials

A

Jonathon Black

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5
Q

The two main considerations of Biological Performance

A

Host Response and Materials Response

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6
Q

Host Response

A

One of the main factors of Biological Performance; Local or systemic response other than the intended therapeutic response of the living system

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7
Q

Materials Response

A

One of the main factors of Biological Performance; the response of the material to the living system

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8
Q

Can a material by itself be biocompatible?

A

NO, size, shape, etc. all matter

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9
Q

A material that elicits a reproducible, quantifiable host response in a standard test.

A

Reference (control) material-can be (-) and elicit no/minimal response or +

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10
Q

A well defined, repeatable test

A

Standard test

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11
Q

Requirements for a material to be biocompatible

A
Non-Toxic
Biochem compatible
Non-irritable
Non-Carcinogenic
Non-immunogenic
Bio Adhesive
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12
Q

Neutrophils ultimately mean

A

Toxicity

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13
Q

move things

A

Phagocytes

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14
Q

three biological rxns to biomaerials

A

Toxicity, inflammation, and mutagens

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15
Q

particulate debris

A

incompatible, no matter the material

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16
Q

How are new materials screened for biocompatibility?

A

By comparing the host response to a reference/control material in a standard test

17
Q

a material that elicits a reproducible, quantifiable, host response in a standard test

A

Reference/Control Material

18
Q

Elicits a minimal response

A

Negative control

19
Q

Elicits an adverse host response

A

Positive control

20
Q

Ceramics biocompatibility?

A

Bioinert

21
Q

CaOH and MTA Biocompatibility

A

Bioactive

22
Q

Calcium phosphates biocomp?

A

Bioactive

23
Q

High purity alumina biocomp?

A

Bioinert

24
Q

How neutrophils find foreign material

A

chemotaxis

25
Q

Chemotactic substances for neutrophils

A

Opsonin, pH, electrochemical

26
Q

Process of phagocytosis

A

Chemotaxis –> invagination of cell –> secondary lysosome formed in cell –> primary and secondary lysosomes form and attack the antigenic substance –> absorbed, degraded, or released