Exam 2 Quiz 6

Question 1

Considers the interactions

that take place between the biomaterial and the host environment.

Answer 1

Biocompatibility

Question 2

Is a biomaterial a property or an event?

Answer 2

An event/interaction

Question 3

Biological performance in a specific application that is judged suitable for that site/situation.

Answer 3

Biocompatible

Question 4

Founder of biomaterials

Answer 4

Jonathon Black

Question 5

The two main considerations of Biological Performance

Answer 5

Host Response and Materials Response

Question 6

Host Response

Answer 6

One of the main factors of Biological Performance; Local or systemic response other than the intended therapeutic response of the living system

Question 7

Materials Response

Answer 7

One of the main factors of Biological Performance; the response of the material to the living system

Question 8

Can a material by itself be biocompatible?

Answer 8

NO, size, shape, etc. all matter

Question 9

A material that elicits a reproducible, quantifiable host response in a standard test.

Answer 9

Reference (control) material-can be (-) and elicit no/minimal response or +

Question 10

A well defined, repeatable test

Answer 10

Standard test

Question 11

Requirements for a material to be biocompatible

Answer 11

Non-Toxic
Biochem compatible
Non-irritable
Non-Carcinogenic
Non-immunogenic
Bio Adhesive

Question 12

Neutrophils ultimately mean

Answer 12

Toxicity

Question 13

move things

Answer 13

Phagocytes

Question 14

three biological rxns to biomaerials

Answer 14

Toxicity, inflammation, and mutagens

Question 15

particulate debris

Answer 15

incompatible, no matter the material

Question 16

How are new materials screened for biocompatibility?

Answer 16

By comparing the host response to a reference/control material in a standard test

Question 17

a material that elicits a reproducible, quantifiable, host response in a standard test

Answer 17

Reference/Control Material

Question 18

Elicits a minimal response

Answer 18

Negative control

Question 19

Elicits an adverse host response

Answer 19

Positive control

Question 20

Ceramics biocompatibility?

Answer 20

Bioinert

Question 21

CaOH and MTA Biocompatibility

Answer 21

Bioactive

Question 22

Calcium phosphates biocomp?

Answer 22

Bioactive

Question 23

High purity alumina biocomp?

Answer 23

Bioinert

Question 24

How neutrophils find foreign material

Answer 24

chemotaxis

Question 25

Chemotactic substances for neutrophils

Answer 25

Opsonin, pH, electrochemical

Question 26

Process of phagocytosis

Answer 26

Chemotaxis –> invagination of cell –> secondary lysosome formed in cell –> primary and secondary lysosomes form and attack the antigenic substance –> absorbed, degraded, or released