Exam 2 Questions

Question 1

P53 is one of these, so is pRb

Answer 1

tumor suppressor

Question 2

A normal cell growth and survival protein is likely a

Answer 2

proto-oncogene

Question 3

This is the % recombinant offspring from a test cross

Answer 3

map units

Question 4

This tends to cause one species to become two species

Answer 4

disruptive selection

Question 5

A protein made then degraded as part of the cell cycle

Answer 5

cyclin

Question 6

Multidrug resistant tuberculosis arises through

Answer 6

directional selection

Question 7

Heredity of genes in human mitochondrial DNA shows

Answer 7

maternal inheritance

Question 8

Programmed cell death or cell suicide

Answer 8

apoptosis

Question 9

Genes used by females to construct their eggs can show

Answer 9

maternal effect

Question 10

A mutation that is in normal body cells, not gametes

Answer 10

somatic

Question 11

This phosphorylates pRb

Answer 11

CDK

Question 12

Allele frequency change that tends to occur in small, isolated populations

Answer 12

genetic drift

Question 13

A tetrad that has both parental and recombinant offspring types

Answer 13

tetratype

Question 14

Small populations often lose genetic diversity because of this

Answer 14

genetic drift

Question 15

Human babies average around 7 lbs due to ____ selection

Answer 15

stabilizing

Question 16

Lee Hartwell, won the Nobel Prize for his work on cdc mutants. These mutants:
a. are conditional
b. include kinases
c. control the cell cycle
d. were isolated in yeast
e. all of the above

Answer 16

e. all of the above

Question 17

If genes assort independently with one dominant and one recessive allele of each gene, a test crossed dihybrid with unlinked genes cross characteristically produces F1 progeny phenotypes in this ratio
a. 1:1
b. 1:2:1
c. 3:1
d. 9:3:3:1
e. 1:1:1:1

Answer 17

e. 1:1:1:1

Question 18

Which of these is not where a cell cycle checkpoint occurs?
a. G1 to S
b. S to G2
c. G2 to M
d. M
e. all of the above have a major checkpoint

Answer 18

b. S to G2

Question 19

Which of the following is not true of cancer genetics?
a. most mutations involved in cancer are somatic
b. it takes many mutations to change a normal cell to a cancer cell
c. one type of cancer has one set of mutations that causes it
d. cancer causing mutations include both gain of function and loss of function mutations

Answer 19

c. one type of cancer has one set of mutations that causes it

Question 20

This is a trait common to all cancers
a. a mutator phenotype
b. gain of function mutations of proto-oncogenes to oncogenes
c. loss of function mutations in tumor suppressors
d. loss of checkpoint control
e. all of these

Answer 20

e. all of these

Question 21

Which of these is not true about the pRB and hereditary retinoblastoma?
a. pRB is a tumor suppressor
b. retinoblastoma tissue has two defective copies of the pRB gene
c. hereditary retinoblastoma inherits as an autosomal recessive
d. pRB helps control the G1 to S transition

Answer 21

c. hereditary retinoblastoma inherits as an autosomal recessive

Question 22

Mitochondrial diseases in humans typically involve
a. cancer
b. immune system problems
c. neuro-muscular problems
d. kidney and liver failure

Answer 22

c. neuro-muscular problems

Question 23

Plants grown from seeds from a flower in a white sector of four o clock plant crossed with pollen from a green sector will be
a. mixed white and green
b. pale green
c. white and will die shortly after sprouting
d. green

Answer 23

c. white and will die shortly after sprouting

Question 24

Which of the following is not true of mitochondrial DNA?
a. it is necessary for cellular respiration in eukaryotes
b. it appears to be the remnants of a bacterial genome
c. it follows basic Mendelian patterns of inheritance but is only seen in females
d. it can cause neuromuscular disease when mutant

Answer 24

c. it follows basic Mendelian patterns of inheritance but is only seen in females