Exam 2- NN Assessment 1+2 Flashcards
The newborn is the first ____ hours after birth
24
The neonatal period consists of:
1st month of neonatal life (28 days)
Trace fetal blood flow starting blood leaving the placenta via the umbilical vein through the fetal circulation and back to the placenta.
Placenta, umbilical vein, ductus venosus, IVC, RA, foramen ovale, LA, LV, Upper body/brain, SVC, RA, RV, ductus arteriosus, distal aorta, lower body, umbilical artery, placenta.
What happens to fetal circulation after birth?
Placental blood flow stops, aortic pressure increases, clamping of the umbilical vein increases SVR, lung expansion decreases PVR, increased PaO2 leads to pulmonary vasodilation.
Discuss the intracardiac pressures during the transition phase. What causes the foramen ovale to close?
Decreased RA pressure + Increased LA pressure leads to closure of the foramen ovale.
When does complete closure of the foramen ovale occur?
2-3months
What causes the closure of the ductus arteriosus?
Increased SVR and Increased PaO2 and decreased PVR leads to constriction of the ductus arteriosus.
When does the ductus arteriosus closure occur?
Functional closure occurs 1-8 days, anatomic closure requires 1-4 months.
When does the ductus venosus close?
Constricts 1-3 hours postnatally. Blood flow into the liver and increase in portal venous pressure.
Fetal breathing begins at ___ weeks
11 weeks, however, this movement decreases throughout pregnancy.
Fetal lung liquid is an ultrafiltrate of plasma with of volume of _____ml/kg
30ml/kg. Partial reabsorption occurs during L/D and 2/3 is expelled during birth.
Retained liquid in the fetal lung can lead to…
Transient Tachypnea of the Newborn (TTN).
Babies 1st breath occurs…
9 seconds after delivery
Lung inflation releases what?
surfactant
Name the 5 parameters of the APGAR
Heart Rate Respiratory Effort Muscle Tone Reflex Irritability Color
How do you score HR on Apgar?
> 100=2
<100=1
Absent=0
How do you score Respiratory effort on Apgar
Robust Crying=2
Irregular, slow, shallow, or gasping resp=1
Absent=0
How do you score reflex irritability on Apgar?
Active coughing and sneezing=2
Grimace=1
No response=0
How do you score Muscle Tone on Apgar?
Active movement=2
Some flexion of extremities=1
Absent/limp=0
How would you score Color on Apgar?
Pink=2
Acrocyanotic (trunk pink, extremities blue)=1
Cyanotic=0
When is Apgar scored?
at 1 min and 5 min after birth
What is a normal Apgar score?
8-10
What Apgar score would signify moderate impairment?
4-7
What Apgar score would require immediate resuscitation?
0-3
Persistent pulmonary HTN the newborn (PPHTNN) may also be called…
Persistent fetal circulation
What are the 3 characteristics of persistent fetal circulation of PPHTNN?
Sustained elevated PVR
Decreased lung perfusion
Continued R-L shunting (PFO and ductus arteriosus)
What is associated with PPHTNN or persistent fetal circulation? (ie factors leading to…)
Severe birth asphyxia Meconium aspiration Sepsis Congenital diaphragmatic hernia Maternal use of NSAIDS
Primary precipitating factors of PPHTNN?
Hypoxemia
Acidosis
Pneumonia
Hypothermia
Other risk factors for PPHTNN?
Maternal diabetes
Maternal asthma
C-Sec delivery
Physiology of PPHTNN?
Elevated PVR->ductus arteriosus and PFO stay open->R-L shunt->hypoxia and normal/elevated PaCo2
Treatment for PPHTNN?
Correcting predisposing disease Mechanical ventilation Exogenous surfactant Inhaled nitric oxide Alkalization ECMO
Respiratory value goals for PPHTNN?
PaO2=50-70mmHg, PaCO2=50-55mmHg
Define Meconium Aspiration Syndrome
Respiratory distress in neonate whose airway was exposed to meconium and CXR shows findings associated with aspiration (consolidation and atelectasis).
Neonatal CO is dependent on what?
Heart Rate
What it the preferred treatment for fetal bradycardia and decreased CO?
Epinephrine
The neonatal ANS is predominantly controlled by SNS or PNS
PNS
What is the blood volume for a neonate?
80-90ml/kg
Give the normal HR for Neonate, 12 mos, 3 year, and 12 year.
Neonate-120bpm
3 mos- 120bpm
3 years- 100bpm
12 years- 80 bpm
Give the normal SBP for Neo, 1 year, 3 year and 12 year
Neo-70-75
1 year- 95
3 year 100
12 year- 110
Give normal DBP for Neo, 1, 3, 12 year
Neo-40
1-65
3-70
12-60
Give EBV for Preemie, Newborn, 3mos-3years, children > 6 and Adults
Preemie- 90-100 Newborn-80-90 3m-3y- 75-80 >6y-65-70 Adults-65-70
The epiglottis lies at ____ in the neonate.
C1
The glottis is ____ at full term, ____for pre-term
C4 full term, C3 neonate
What shape is the neonatal epiglottis?
Omega
The babies 1st breast establishes what
FRC
The vocal cords are ____ slanted
anterior
The larynx lies at
C2-C4
The majority of neonates are preferential ____ breathers
nose
The tongue is (large/small) compared to mouth opening.
large
Term fetus Po2, PCo2 and pH before labor?
Po2-25
PCo2-40
pH 7.37
Term fetus Po2, PCo2, and pH at end of labor?
Po2-10-20
PCo2-55
pH- 7.25
MV:FRC is ______ x higher in newborn
2-3x higher than that of an adult
Describe the types of fibers in the newborn and which is predominate
Type 1 Slow twitch
Type 2 Fast twitch- more predominate in newborn, so more likely to fatigue easily.
Stimulation of the carina or SLN will lead to….
Respiratory depression/apnea, following upper AW obstruction or lung hyperinflation (Hering - Breuer reflex).
RR rate of Infant compared to Adult
Infant RR is 30-50
Adult RR is 12-16
TV of Infant compared to Adult
Tidal Volumes
Infant 7ml/kg
Adult 7ml/kg
SAME SAME
FRC of Infant compared to Adult
Infant FRC-27-30/kg
Adult-30ml/kg
Infant is slightly less
O2 consumption of infant compared to Adult
Infant 7-9 ml/kg/min (more)
Adult 3 ml/kg/min (less)
Nervous system is complete by age…
3 years old
Peripheral Nervous system begins in
motor roots
Cerebral nerves system begins in
sensory system
The diaphragm is more responsive to which type of NMBs?
NDMRs
Signs of pain in newborn
Tachycardia Elevated BP Crying Restlessness Grimacing
The Conus Medullaris terminates between ____ in neonates
L2-L3
Primary source of fuel in the neonate?
Glucose- has decreased stores- hypoglycemia is a maj source of morbidity
Which is more responsive in the newborn, SNS or PNS
PNS- so stress/hypoxemia causes bradycardia
Liver is not fully functional at birth, my see ______ develop in the 1st few days of life.
Hyperbilirubinemia (6-8mg/ml)
Clotting factors also may be low
Neonate has ____ GFR.
Low (1-2ml/kg/min)
GFR _____ by 2 weeks of age
doubles
4 reasons newborns have low GFR
Low systemic arterial pressure
High renal vascular resistance
Low permeability of the glomerular capillaries
Small size and number of glomeruli
The kidneys are 60-70% mature by
1 month
GFR reaches normal levels by
12-24 months
What ml/kg/hr of urine would indicate hypovolemia or decreased renal function in a newborn
<1ml/kg/hr = Hypovolemia or decreased renal function
Half life of meds that are excreted by GFR are (reduced or prolonged)
prolonged
How do newborn tolerate fluid overload?
poorly
Newborns are Obligate _____ excreters
obligate SODIUM excreters
TBW is about ____% for Term infant
75%
Preterm TBW is ____%
80-85%
Factors for increased heat loss in neonate?
Cold environment
High ratio of surface area to body weight
Reduced SubQ fat
Poor shiver response to cold
Newborn response to cold
Increasing metabolic rate and releasing norepinephrine- non-shivering thermogenesis. “Brown fat Thermogenesis”
Conus medullaris is located at _____ in neonates and infants
L3
Conus medullaris reaches ____ at 1 year of age (and stays throughout adulthood)
L1
LP for SAB?
L4-L5,L5-S1
Skin to SAS in neonate? cm
1.4cm
Respiratory causes of neonatal bradycardia and cardiac arrest
AW obstruction Bronchospasm Pulmonary Aspiration Inadequate O2 delivery Pneumothorax
Pharmacologic causes of neonatal bradycardia and arrest
Inhalation agents
Succinylcholine
Anticholinesterases
Neurogenic causes of neonatal bradycardia and arrest
Celiac reflex
Oculocardiac Reflex
Superior/Recurrent nerve stimulation
Metabolic causes of neonatal bradycardia and arrest
Hypoglycemia
Anemia
Hypothermia
Acidosis
Spinal Anesthesia doses for newborn
1% Tetracaine in 5% Dextrose 0.6-1mg/kg
- 5% Bupivi 0.5-1mg/kg
- 75% Bupivi in 8.25% dextrose 0.5-1mg/kg
Steps for performing a Caudal Block
Lateral position, upper knee flexed
Landmarks: tip of coccyx, sacral cornua
22g needle, bevel up at 45 deg angle to skin
Feel LOR, reduce needle angle and advance CEPHALAD
Volume determines height of block (think epidural)
1.2-1.5ml/kg provide anesthesia/analgesia to T4-T6
DONT USE MORE THAN 2.5 mg/kg
Which blade is preferable for infants?
Straight blade
ETT sizes for Preterm, Full Term, 3-12 months
Pre term- 2-3
Full term- 3-3.5
3-12 months- 4.0
Shortcut- look at pinky finger
Allow for air leak at
20-30cm H2O
Length of insertion of ETT
<10cm, between 8-10cm