Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

RUSVM SAM II > Exam 2 Immune Mediated Diseases > Flashcards

Exam 2 Immune Mediated Diseases Flashcards

1
Q

Which of the following is false regarding IMHA?

a. Associated with a Type 3 HST reaction
b. Primary IMHA have a mortality between 21 and 83%
c. Half of the deaths are associated with thromboembolism
d. Cocker spaniel female dogs are more commonly affected

A

a. Associated with a Type 3 HST reaction

**Type 2 HST reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which immunoglobuins predominate IMHA?

A

IgM and IgG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

True/False: splenomegaly and hepatomegaly are assocaited with intravascular hemolysis.

A

False

**extravascular hemolysis, IV hemolysis causes Hgbinemia and Hgburia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

With extravascular hemolysis ___ attach to the RBC and with intravascular hemolysis ___ attach to the RBC.

A 
Extravascular = IgG
Intravascular = IgM
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

True/False: The majority of canine and feline IMHA are secondary.

A

False

**primary/ idiopathic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which of the following is not seen on diagnostics with IMHA?

a. Left shift neutrophilia
b. Hemolysis
c. Spherocytosis
d. Decreased reticulocytes
e. Incrased normoblast (nRBC)

A

d. Decreased reticulocytes

**increased reticulocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which test looks for direct auto-antibodies against erythrocytes?

A

Coomb’s test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

When calculating a blood transfusoin in dogs what is the k value that we used? What is the value in cats? What is the PCV required for both?

A

Dogs: 90
Cats: 66
Required PCV = 25%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which of the following is false regarding blood groups?

a. DEA 4 is the universal donor in dogs
b. Type A blood is more common in cats
c. DEA 1.1 positive is good and its the one dogs will most likely react to
d. First time recipients can get any blood group

A

c. DEA 1.1 positive is good and its the one dogs will most likely react to

**DEA 1.1 negative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the best immmunosuppressive drug that can be combined with azathioprine?

A

Prednisolone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What drug can be used to prevent coagulopathy and is better than aspirin?

A

Unfractionated heparin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

When using unfractionated heparin we need to monitor factor ___ levels to prevent bleeding

A

factor X

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What three things are most deaths of IMHA attributed to?

A

Thromboembolism, renal failure, liver disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which of the following is not seen with DIC?

a. Increased FDP
b. Prolonged PTT
c. Thrombocytopenia
d. Decreased FDP

A

d. Decreased FDP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

An 18 kg dog is diagnosed with primary IMHA. Its PCV is currently 12% and you use packed RBC (PCV 70%). How much blood is required in mL?

A

300.8 mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Primary hemostasis refers to the action of what three things culminating in the formation of a platelet plug?

A

Platelets
von-Willebrand factor
Blood vessel wall

17
Q

Platelet formation is mediated through which hormone produced in the liver and kidneys?

A

Thrombopoietin

18
Q

A dog presents to your clinic reluctant to walk, stiff and has a high grade fever. You aspirate one of the multiple swollen joints in his limbs and notice that neutrophils are the cells that predominate. What is at the top of your diagnosis list?

a. Immune mediated hemolytic anemia
b. Immune mediated thrombocytopenia
c. Immune mediated polyarthritis
d. Systemic lupus erythematosis

A

c. Immune mediated polyarthritis

19
Q

A dog walks into your clinic and presents with petechia, echymosis, and epistaxis. His platelet count is <30,000. What is at the top of your diagnosis list?

a. Immune mediated hemolytic anemia
b. Immune mediated thrombocytopenia
c. Immune mediated polyarthritis
d. Systemic lupus erythematosis

A

b. Immune mediated thrombocytopenia

20
Q

A dog comes into your clinic presenting with dyspnea, anorexia, icterus, PU/PD. You decide to do a blood smear because you believe he is anemic and you see spherocytes and increased normoblasts. What is your diagnosis?

a. Immune mediated hemolytic anemia
b. Immune mediated thrombocytopenia
c. Immune mediated polyarthritis
d. Systemic lupus erythematosis

A

a. Immune mediated hemolytic anemia

21
Q

You have a 3 year old dog that comes into your clinic presenting with lameness, skin lesions, fever and renal disease. What is at the top of your diagnosis list?

a. Immune mediated hemolytic anemia
b. Immune mediated thrombocytopenia
c. Immune mediated polyarthritis
d. Systemic lupus erythematosis

A

d. Systemic lupus erythematosis

22
Q

Which of the following breeds is not predisposed to von-Willebrands disease?

a. Dobermans
b. Bernese mountain dogs
c. German Shepherds
d. West highland white terrier
e. Goldendoodle

A

c. German Shepherds

23
Q

What can be used 30 minutes prior to surgery in a dog with Von-Willebrand’s disease to improve hemostatic function?

A

Desmopressin

24
Q

What is the 1st line treatment used to treat ITP?

A

Glucocorticoids and vincristine

25
Q

Which of the following is the best first line therapy if glucocorticoids are contraindicated?

a. Azathioprine
b. Cyclophosphamide
c. Cyclosporine
d. Mycophenolate mofetil

A

d. Mycophenolate mofetil

26
Q

Which of the following is the best source of PLT’s?

a. Lyophilized PLT
b. Packed RBC
c. Fresh whole blood
d. Fresh PLT rich plasma

A

c. Fresh whole blood

27
Q

What breed is associated with non-erosive primary ITP?

A

Shar-Pei

28
Q

Which breed is associated to have a poor prognosis with erosive ITP?

A

Greyhound

29
Q

What are the two forms of feline periosteal proliferative arthritis?

A

Marked periosteal proliferation

Minimal periosteal new bone (rheumatoid arthritis)

30
Q

True/False: With SLE we need at least two separate manifestations of autoimmunity and the presence of antinuclear antibodies.

A

True

31
Q

What diagnostic test is used for SLE?

A

ANA titers

32
Q

Which of the following is true regarding treatment of SLE?

a. Mycophenolate mofetil can be used in cats
b. Chlorambucil can be used in dogs
c. Triamcinolone or dexamethasone can be used in dogs that don’t respond to prednisolone
d. Triamcinolone or dexamethasone can be used in cats that don’t respond to prednisolone

A

d. Triamcinolone or dexamethasone can be used in cats that don’t respond to prednisolone

RUSVM SAM II (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions