Exam 2 - HTN Flashcards

1
Q

What BP is considered htn?

A

> 140/90

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2
Q

Why do we worry about HTN?

A

it can lead to stroke, HF, LVH

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3
Q

Which type of HTN has an unknown etiology, and is 2x greater in blacks?

A

essential (primary)

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4
Q

Which type of htn is from renal, endocrine, or congenital disease?

A

secondary

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5
Q

what factors can worsen htn?

A

fat

salty diet

cigs

nsaids

excess alcohol

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6
Q

what are the causes of htn?

A

genetics, enviro

inc SNS activity

inc RAA axis

high sodium

endocrine problem

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7
Q

does estrogen cause primary or secondary htn?

A

secondary

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8
Q

what can htn lead to in the heart?

A

chd, lvh, hf

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9
Q

what can htn lead to in the brain?

A

cerebrovascular disease

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10
Q

what else can htn lead to?

A

PAD

renal disease

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11
Q

which 3 things can cause kidney hypertension (a cause of 2ndary htn)?

A

renal artery stenosis

hyperplasia (FMH)

atherosclerosis

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12
Q

which comorbidity is associated with morbidity and mortality?

A

LVH

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13
Q

does LVH cause systolic or diastolic dysfunction?

A

diastolic

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14
Q

once you have LVH, can it regress?

A

YES with treatment

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15
Q

is cerebrovascular disease related to systolic or diastolic pressure?

A

systolic

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16
Q

what are the early symptoms of htn?

A

asx

morning headaches

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17
Q

what are late symptoms/findings of htn?

A

LVH causes SOB, DOE

Cerebral - TIA, stroke, hemorrhage

Heart - MI, angina, HF

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18
Q

What will you see in the retina on PE?

A

AV nicking

silver or copper wiring

hemorrhages or exudates

papilledema

19
Q

What two lab levels are you especially looking for in htn?

A

creatinine, BUN

for renal function

20
Q

What are treatment goals for someone over 60y?

A

bp < 150/90

Ideal goal is 140 systolic

21
Q

What are treatment goals for someone under 60y

A

bp < 140/90

22
Q

what are treatment goals for anyone over 18y with DM and CKD?

A

bp < 140/90

23
Q

What is ideal treatment for HTN in a non-black?

A

thiazide diuretic

CCB

ACE-I/ARB

24
Q

what is the ideal treatment for HTN in blacks?

A

thiazide diuretic

CCB

25
What is ideal tx for someone 18+ with HTN and CKD?
ACE-I/ARB
26
What is ideal tx for HTN after an MI?
add BB to whatever
27
what is ideal treatment for HTN + HF?
ACEI
28
ideal treatment for HTN + angina
CCB 1st line BB 2nd line
29
ideal treatment for HTN + DM?
ACEI/ARB +/- thiazide diuretics or CCB
30
How many meds is a hypertensive diabetic patient on on average?
3
31
Ideal treatment for someone with HTN and trouble urinating?
alpha blockers
32
What are the treatment guidelines for a person whose BP is \>160 systolic or \>100 diastolic?
start with 2 drugs
33
34
Non pharm treatment for HTN?
diet - low fat, low dairy, low ETOH, low Na diet - high fruits, high veggies, high fiber weight reduction aerobic exercise smoking cessation
35
What's the DOC in htn?
**thiazide diuretics** | (a part of ANY drug combo)
36
what do thiazide diuretics decrease?
SVR
37
who do thiazide diuretics work better in?
blacks, elderly
38
which type of htn are thiazides best for?
isolated systolic htn
39
Which drug is less effective in blacks and the elderly?
beta blockers
40
which selective beta blocker is effective in HTN as well as HF and erectile dysfunction?
Nebivolol
41
MOA of nebivolol?
vasodilates via nitric oxide
42
are ACE-I useful as a primary med or as adjunct?
either but work best with diuretics
43
are direct renin inhibitors like aliskeren better as monotherapy or adjunct?
either
44
So CCBs are good for HTN but if a person has HF, you can't give nondihydropyridines. Why can't you?
they're inotropic and slow AV conduction