Exam 2 final Flashcards
What are the two subdivisions of the cardiovascular system and their functions?
Pulmonary circuit:
Systemic circuit:
Pulmonary circuit:
Carries blood to and from the lungs for gas exchange.
Systemic circuit:
Carries oxygenated blood to the body and deoxygenated blood back to the heart.
Describe the three layers of the heart wall and their histological differences.
Epicardium: Outer layer, connective tissue and epithelial cells.
Myocardium: Middle layer, thick cardiac muscle.
Endocardium: Inner layer, smooth endothelial cells.
Chambers:
Left and right atria, left and right ventricles.
Valves:
Tricuspid (right atrium to right ventricle),
bicuspid/mitral (left atrium to left ventricle),
pulmonary (right ventricle to pulmonary artery),
aortic (left ventricle to aorta).
Fibrous skeleton:
Dense connective tissue supporting the heart’s structure and valve function.
Great vessels:
Aorta, superior and inferior vena cava, pulmonary arteries, and pulmonary veins.
Chordae tendineae:
Tendons that connect the papillary muscles to the heart valves.
Papillary muscles:
Contract to prevent valve prolapse.
Contractile cells:
Generate force for heart contraction.
Left ventricle:
Thickest wall, pumps blood to the body.
Atria:
hinner walls than ventricles, receive blood.
Describe the cardiac conduction system and the path of electrical signals.
Path: SA node → AV node → Bundle of His → Right and Left Bundle Branches → Purkinje fibers.
Right ventricle:
Thinner wall, pumps blood to the lungs.
Autorhythmic cells:
Set heart rhythm (SA node, AV node).
What is the chronological order of cell excitation and muscular contraction?
Excitation: SA node → atrial depolarization → AV node → ventricular depolarization → repolarization.
What is the cause of heart sounds?
Heart sounds are caused by the closure of heart valves (S1, S2).
Explain the mechanism of rhythmic depolarization in the SA node.
The SA node depolarizes due to pacemaker potentials (slow Na+ influx, followed by Ca2+ influx) leading to an action potential.
Diastole:
Relaxation phase of the heart.`
Systole:
Contraction phase of the heart.
Explain how contractile cells depolarize, show a plateau, and repolarize.
Depolarization: Na+ influx.
Plateau: Ca2+ influx and K+ efflux.
Repolarization: K+ efflux.