Exam 2 DRUGS ONLY Flashcards

1
Q

Alpha 1 receptors

A

vascular smooth muscle,

skin, kidney, viscera, skeletal

NE binding leads to vasoconstriction

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2
Q

Alpha 2 receptors

A

Presynaptic ganglia

auto inhibition of NE

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3
Q

Beta 1 receptors

A

Heart, Epi/NE

induces contractility, heart rate, velocity

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4
Q

Beta 2 receptors

A

pulmonary airways, skeletal muscle vasculature

auto stim of NE at presynaptic ganglia

VASODILATION

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5
Q

Dopamine

A

Beta agonist- lead to vasodilation

tx acute renal vailure- increase perfusion to kidneys

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6
Q

Dobutamine

A

beta 1

tx congestive heart failure

acts as positive ionotrope

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7
Q

Ephedrine

A

Alpha/Beta agionist

beta lipolysis/thermogenic

Tx urinary incontince/hypotensiono

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8
Q

Phenylephrine

A

alpha agonist

pupillary dilation, hypotension/hypovolemic shock

alpha stim leads to vasoconstriction

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9
Q

Albuterol

A

beta 2 agonist

bronchodialtion

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10
Q

CLenbuterol

A

tx COPD, banned in horses

beta 3 stim/bronchodialtion

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11
Q

Terbutaline

A

long lasting beta 2,

takes longer to take effect

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12
Q

Propanolol

A

beta blocker, not beta 1 specific

risk blocking beta 2, leads to bronchoconstriction

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13
Q

Atenelol

A

beta 1 specific

used for high blood pressure

anti anxiety

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14
Q

Phenbenzamine

A

alpha 1/2 antagonist

decreases urethral sphincter tone, laminitis

leads to vasodialtion of peripheral vessels-> increases peripheral perfusion

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15
Q

Phentolamine

A

alpha 1/2 blocker

save fingers injected w/ epi

also tx pheochromatomas- adrenal gland tumors, reduces effect of too much epi

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16
Q

Carbacol

A

Cholinergic receptor agonist

17
Q

Bethanecol

A

Muscarinic recptors agonist

used for bladder stimualtion (M3)

18
Q

Pilocarpine

A

muscarinic receptors agonist

tx keratoconjunctivitis, glaucoma (M3)

causes pupil constriction

19
Q

Edrophonium/Pyridostigme

A

Tx Myasthenia Gravis

cholinesterase inhibitors- prevent breakdown of Ach

20
Q

atropine

A

Revers effect of Organophosphates; muscarinic receptor antagonist

21
Q

Tx for hormonal incontinence?

A

DES- Oral Diethylstillbestrol

Phenylpropanolamine PPA

22
Q

Tx Urge incontinence

A

Oxybutynin (M3 antagonist)