Exam 2 DRUGS ONLY Flashcards
Alpha 1 receptors
vascular smooth muscle,
skin, kidney, viscera, skeletal
NE binding leads to vasoconstriction
Alpha 2 receptors
Presynaptic ganglia
auto inhibition of NE
Beta 1 receptors
Heart, Epi/NE
induces contractility, heart rate, velocity
Beta 2 receptors
pulmonary airways, skeletal muscle vasculature
auto stim of NE at presynaptic ganglia
VASODILATION
Dopamine
Beta agonist- lead to vasodilation
tx acute renal vailure- increase perfusion to kidneys
Dobutamine
beta 1
tx congestive heart failure
acts as positive ionotrope
Ephedrine
Alpha/Beta agionist
beta lipolysis/thermogenic
Tx urinary incontince/hypotensiono
Phenylephrine
alpha agonist
pupillary dilation, hypotension/hypovolemic shock
alpha stim leads to vasoconstriction
Albuterol
beta 2 agonist
bronchodialtion
CLenbuterol
tx COPD, banned in horses
beta 3 stim/bronchodialtion
Terbutaline
long lasting beta 2,
takes longer to take effect
Propanolol
beta blocker, not beta 1 specific
risk blocking beta 2, leads to bronchoconstriction
Atenelol
beta 1 specific
used for high blood pressure
anti anxiety
Phenbenzamine
alpha 1/2 antagonist
decreases urethral sphincter tone, laminitis
leads to vasodialtion of peripheral vessels-> increases peripheral perfusion
Phentolamine
alpha 1/2 blocker
save fingers injected w/ epi
also tx pheochromatomas- adrenal gland tumors, reduces effect of too much epi
Carbacol
Cholinergic receptor agonist
Bethanecol
Muscarinic recptors agonist
used for bladder stimualtion (M3)
Pilocarpine
muscarinic receptors agonist
tx keratoconjunctivitis, glaucoma (M3)
causes pupil constriction
Edrophonium/Pyridostigme
Tx Myasthenia Gravis
cholinesterase inhibitors- prevent breakdown of Ach
atropine
Revers effect of Organophosphates; muscarinic receptor antagonist
Tx for hormonal incontinence?
DES- Oral Diethylstillbestrol
Phenylpropanolamine PPA
Tx Urge incontinence
Oxybutynin (M3 antagonist)
