Exam 2 Chapter 6 Flashcards
DNA building blocks
- 2 purines
- Adenine
- Guanine
- Both for DNA & RNA
- 2 Pyrimidines
- Cytosine for DNA
- Thymine for RNA
Backbone of deoxyribose
5 carbon sugar
Nitrogenous base
Purine or pyrimidines
Base + sugar =
Nucleoside
Base + sugar + phosphate
Nucleotide
Nucleosomes
Core of 8 histones w/ DNA wrapped around
Double stranded DNA + small basic proteins (histones) + small amount of non histone proteins
Chromatin
Histones
- Arginine & lysine rich basic proteins
- Positive charge on AA helps to negative charge on DNA sugar phosphate
DNA repeats at chromosome ends that protect it from degradation
Telomere
Attach during mitotic cell cycle
Centromere
Ploidy
Number of chromosome couples in a cell
Most cells in the body are:
Diploid
Germ cells are:
Haploid
miRNA
Control translation & post translational changes
Epigenetics controlled by:
Methylation of cytosines