Exam 2 Chapter 6 Flashcards

1
Q

DNA building blocks

A
  • 2 purines
    • Adenine
    • Guanine
    • Both for DNA & RNA
  • 2 Pyrimidines
    - Cytosine for DNA
    - Thymine for RNA
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2
Q

Backbone of deoxyribose

A

5 carbon sugar

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3
Q

Nitrogenous base

A

Purine or pyrimidines

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4
Q

Base + sugar =

A

Nucleoside

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5
Q

Base + sugar + phosphate

A

Nucleotide

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6
Q

Nucleosomes

A

Core of 8 histones w/ DNA wrapped around

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7
Q

Double stranded DNA + small basic proteins (histones) + small amount of non histone proteins

A

Chromatin

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8
Q

Histones

A
  • Arginine & lysine rich basic proteins

- Positive charge on AA helps to negative charge on DNA sugar phosphate

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9
Q

DNA repeats at chromosome ends that protect it from degradation

A

Telomere

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10
Q

Attach during mitotic cell cycle

A

Centromere

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11
Q

Ploidy

A

Number of chromosome couples in a cell

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12
Q

Most cells in the body are:

A

Diploid

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13
Q

Germ cells are:

A

Haploid

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14
Q

miRNA

A

Control translation & post translational changes

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15
Q

Epigenetics controlled by:

A

Methylation of cytosines

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16
Q

_________ of lysine weakens DNA-histon interaction- easier for transcription factors to access

A

Acetylation of lysine

17
Q

Histone _______ makes interactions tighter & is associated with gene silencing

A

Histone deacetylase (HDAC)

18
Q
  • Loosely packed
  • transcriptionally active
  • Gene sequence available to RNA polymerases
A

Euchromatin

19
Q
  • Densely packed regions

- Genetically inactive

A

Heterochromatin