Exam 2: Ch 19 Endocardial & Valve Disorders Flashcards
infective endocarditis
infection of endocardium including valves
vegetative growth on valve leaflets –> regurgitation
septic emboli break free from growths
requires both heart damage and introduction of the organism – dental work in person w/ valve disease
infective endocarditis is most commonly seen in people with…
preexisting heart defects
IV drug use: staph. A
heart surgery: staph. epidermis from prosthetic valve
symptoms of infective endocarditis
systemic infection
petechial (pinpoint) hemorrhages from emboli
diagnosis and treatment of infective endocarditis
Dx: blood cultures and echo for regurgitation
Rx: antibiotics, treat cardiac symptoms
rheumatic heart disease
immune response to beta-hemolytic strep infection
symptoms of rheumatic heart disease
sore throat and swollen glands
carditis –> heart murmur and friction rub
polyarthritis of large joints
skin lesions
CNS involvement –> choreiform movements (jerking)
diagnosis/treatment of rheumatic heart disease
Dx: clinical picture, echo, presence of anti-strep Ab
Rx: prevent by treating strep throat
antibiotics to control infection
anti-inflammatories to limit valve damage
2 types of valvular heart disease
stenotic: produce resistance to forward blood flow
incompetent (regurgitate) valves: close incompletely, producing backflow
mitral stenosis
mitral valve doesn’t open all the way, often from fused leaflets from RHD
LV fills poorly (low SV and CO)
LA pressure is increased (pulmonary congestion)
symptoms of mitral stenosis
less CO: chest pain, weakness, fatigue
pulmonary congestion: SOB, AF, thrombi, Rt side HF
diastolic murmur
mitral regurgitation
mitral valve fails to close fully
retrograde flow into LA during systole –> systolic murmur
high LAP leads to high SV, but low forward SV
enlarged LV b/c volume work increased
eventually LV function is impaired
causes of mitral regurgitation
RHD
mitral valve prolapse
chordea tenineae/papillary muscle rupture
mitral valve prolapse
caused by Marfan’s syn, other conn. tissue disorders
beta blockers relieve symptoms
antibiotic prophylaxis to prevent complications
can cause mitral regurgitation
aortic stenosis
narrowed aortic valve increases resistance to LV ejection
pressure work of LV increased, SV decreased
systolic BP lowered, but LVP increased
systolic murmur
causes and symptoms of aortic stenosis
causes: congenital defect, acquired calcification
symptoms: angina, syncope (fainting), HF