Exam 2: Breast Cancer Flashcards
Risk factors of breast cancer
- personal history of breast cancer
- family history
- certain breast changes
- gene changes
- reproductive & menstrual history
- radiation therapy to the chest
- DES (diethylstillbestrol)
- exposure to estrogen like chemicals
- being obese/overweight after menopause
- breast density
- alcohol
name two types of breast cancer
Non-invasive
- lobular carcinoma in situ (LCIS)
- Ductal carcinoma in situ (DCIS)
Invasive
- ductal
- Lobular
Inflammatory breast cancer
what is ductal carcinoma in situ
proliferation of malignant cells inside the milk ducts without invasion into the surrounding tissue
what is invasive breast cancer
tumors arise from duct or lobular system and invade surrounding tissues
what is the most common breast cancer type
ductal carcinoma
which genes are associated with increased risk
BRCA1 and BRCA2
signs and symptoms
- nontender, palpable, irregularly shaped, fixed mass
- dimpling, peau d’orange, incr vasculature
- nipple discharge and retraction
- Asymmetry of breast
- enlarge axillary lymph nodes
- tenderness or soreness around the mass
early signs and symptoms and late signs and symptoms
early signs and symptoms:
none
late signs and symptoms:
skin dimpling, nipple retraction, or skin ulceration
diagnosis
- BSE (breast self exam(
- CBE (clinical breast exam)
- Mammography
- CT scan, MRI
- Biopsy
What is the BRCA1 and BRCA2 gene?
genes that normally suppress tumors. however, when gene mutate they can cause cancer
2 chemo meds used from prevention?
tamoxifen and raloxifene
protective factors
- 30-60 mins of exercise
- breastfeeding decr. return of period –> decr. estrogen
- decr. stress
when should women start breast exams?
BSE: early 20s told about benefits and limitations, report new symptoms
CBE: early 20s and 30s every 3 yrs and asymptomatic women periodically over 40
Mammography: begin annually after 40
what is the proper timing of a BSE
premenopausal: 5 to 7 days after period
postmenopausal: once a month
steps of BSE
- in front of mirror, check breasts discharge, puckering, dimpling, or scaling
- check contour: clasp hands behind head and press forward
- check contour: press hands on hips and bow slightly. pull elbow and shoulders forward
- raise left arm, w/ 3 or 4 fingers feel around breasts w/ circular motion working towards nipple
- repeat step 4 but lying down
2 types of surgery
- breast conserving
2. non-breast conserving