Exam 2, B12

Question 1

B12 coenzyme

Answer 1

B12

Question 2

B12 and antibiotics

Answer 2

antibiotics grow animals by inhibiting growth of microorganisms that destroy B12
so increased antibiotics = increased B12

Question 3

what does intrinsic factor do

Answer 3

protein IF made in stomach, helps intestines absorb B12

Question 4

measure of B12 status

Answer 4

transcobalamin II (transport protein)

Question 5

MAIN function B12

Answer 5

coenzyme that is used for the transfer of methyl groups, such as in folic acid -> THF

Question 6

secondary function B12

Answer 6

overall growth factor, anemia prevention

Question 7

methionine synthase

Answer 7

needs B12 for conversion of homocysteine to methionine

Question 8

methylmalonyl-coA mutase

Answer 8

conversin of L-methylmalonyl to succinyl-CoA

Question 9

odd chain fatty acids and B12

Answer 9

B-oxidation uses B12 to enter the kreb’s cycle through succinyl coA to produce energy

Question 10

photo black and white, on top large, darker blood cells and on the bottom small, light blood cells

Answer 10

1. pernicious anemia (top) : B12
2. normal anemia, iron deficiency or microcytic anemia : iron, folte