Exam 2 Flashcards
Warning signs for skin CA
open sore that does not heal for 3 weeks, a spot or sore that burns, itches, stings, crusts or bleeds; any mole or spot that changes in size or texture, develops irregular borders, or appears pearly, translucent, or multicolored
Skin photaged by sun damage
Coarse with yellow discoloration (solar elastosis), irregularly pigmented, rough or atrophic with deep wrinkling
ABCDE screening for MM
asymmetry, border irregularities, color, diamet >6mm, elevation
Shave or punch biopsy for
non-melanocytic skin cancer
Excisional biopsy for
MM
Solar actinic keratosis
Pre-malignant
Disorder of pilosebaceous follicles causing increased sebum production, keratinization, inflammation, and bacterial colonization
Acne Vulgaris
Blackhead
Obstruction of follicle filled with stratum corneum cells
Open comedone
Whitehead
Cystic swelling of the comedone–precursor of inflammatory papules and pustules
Closed comedone
Length of time for acne treatment
6-12 weeks to be effective
First line therapy for acne
Topical
Trentinoin (Retin A), Adapalen, tazarotene, benzoyl peroxide, salicylic acid
Tx for inflammatory acne
Erythromycin, clindamycin, metronidazole, sulfonamide, azelaic acid
Oral abx for severe acne
Erythromycin, tetracycline, doxycycline, minocycline
Rosacea
age 30-50
No comedones
Facial flushing, facial erythema, inflammatory papules and pustules, edema, watery or irritated eyes
Avoid triggers
Tx of acne rosacea
Topical metronidazole, azelaic acid, sulfacetamide-sulfur
Signs of compartment syndrome
Pain, pallor, paresthesia, paralysis
Tx of bite wounds
Irrigate with 150ml sterile saline solution, tetanus vaccine, do not suture
Prophylactic abx for bite wounds
Augmentin 875mg/125mg BID for 5-7 days
superficial or partial thickness burns involving only the epidermis—glossy, red and painful
First degree
partial thickness burn involving the dermis—dull or glossy with pink, red or white pigmentation; may blister and be severely painful
2nd degree burn
full thickness burns that extend to subcutaneous fat—matte and may be white, brown, red, or black loss of sensation
3rd degree burn
Management of 1st degree burn
Cool tap water, closed wound dressing (silver sulfadiazine cream–silvadene), gels, hydrocolloids, aloe vera
Most prevalent organisms in cellulitis
Group A strep
Staph if deep penetrating wounds
spreading erythema, warmth, induration and pain, possible lymphadenitis
Cellulitis
Tx of mild cellulitis
Penicillin, amoxicillin, augmentin, cephalexin, clindamycin
Tx for purulent cellulitis
Bactrim, doxycycline, cephalexin, dicloxacillin
ED
exophthalmos, orbital pain, restricted eye movement, occasional visual disturbances
Orbital cellulitis–medical emergency
Irritant contact dermatitis
Due to direct cytotoxic action of an agent on the cells of the epidermis and dermis
Ex. Soaps, detergents, acids, alkalis
lichenification, scaling, fissuring
Most common cause of allergic contact dermatitis
nickel, neomycin, bacitracin, poison ivy or oak
Diagnostics for contact dermatitis
KOH slide, cultures, inspection
Tx of contact dermatitis
- avoid offending agent
2. medium to high dose steroid ointments
grouped round vesicles containing cloudy fluid on an erythematous base
Herpes
Diagnostic test for herpes
Tzanck smear or PCR
Tx of herpes
Acyclovir 400mg PO TID for 7-10 days OR acyclovir 200mg PO 5X day for 5 days
How to diagnose fungal infections
Woods lamp
Tx of pain in shingles
Gabapentin, amitryptiline
Narcotics do not help
Diagnostics for shingles
Tzanck test, PCR
Tx of shingles
Antiviral within 72 hours
Topical agents for anesthetic–lidocaine patch, NSAID patch, capsaicin cream
well-circumscribed erythematous macular and papular lesions with loosely adherent silvery white scale
Psoriasis
Tx of psoriasis
Potent topical steroid + vitamin D analog first line
Systemic: oral retinoids, methotrexate, cyclosporine
Tx of refractory psoriasis
Methotrexate
Tx scabies
Topical permethrin–leave for 8-12 hours, wash off and repeat in 1-2 weeks
Antihistamine for itching
Tx of seborrheic dermatitis
Topical antifungals or steroids
Shampoos: keoconazole, selenium sulfide 1-2 times per week for 4 weeks
hemosiderin staining of skin—due to decreased blood flow to legs
Stasis dermatitis
Tx of stasis dermatitis
Compression therapy gold standard, topical emollients daily, systemic abx if cellulitis, topical steroids for itching
o Edematous pink or red wheals surrounded by bright red flare with pruritus
Hives
Tx for hives
Antihistamines first line–loratadine, cetirizine, fexofenadine, desioratadine
TCAs may be used
Classic triad of ruptured abdominal aortic aneurysm
Hypotension, pulsatile abdominal mass, abdominal or back pain
Who should undergo US screening for detection of aortic aneurysm
Men 60 years of age and older who are either a sibling or offspring of someone with AAA
Men who are 65-75 who have ever smoked
Pathophysiology of carotid artery disease
Carotid stenosis due to plaques and atherosclerosis
visual disturbances, monocular blindness (amaurosis fugax), weakness or numbness of the contralateral arm, leg or face, dysarthria, aphasia
Carotid stenosis
Modifiable risk factors for carotid artery disease
high BP, smoking, hyperlipidemia, DM, hyperhomocysteinemia, obesity, nutrition, physical inactivity, CKD, heavy alcohol use, sleep apnea, depression
First line diagnostic for carotid artery disease
Duplex ultrasound
Tx for carotid artery disease
Aspirin + statin + management of hypertension
dyspnea and fatigue, lower extremity edema, JV, patient’s history, ROS, and physical exam findings
Heart failure
Tx of heart failure
ACEI, Beta blockers, hydralazine, oral nitrates, aldosterone, loop diuretics, digoxin
Cough in HF
Moist and productive
Goal BP in hypertension
<140/90 <60 years or <150/90 if older than 60 (JNC 8 recommendation)
TX of hypertension in non-black with or without diabetes
Thiazide diuretic, CCB, ACEI, ARB
Tx of hypertension in black individual
Thiazide diuretic of CCB
Tx of hypertension in diabetic
ACEI
Hypertensive emergency
Hypertensive encephalopathy Intracranial hemorrhage Unstable angina pectoris Acute myocardial infarction Pulmonary edema Eclampsia
Hypertensive urgency
Upper levels of stage 2 hypertension
Hypertension with optic disc edema
Progressive target organ complications
Severe perioperative hypertension
Stepwise tx in hypertension
Thiazide diuretic + ACEI/ARB/ beta blocker/ CCB