Exam 2 Flashcards
What do estrous and menstrual cycles provide females with?
Repeated opportunities to become pregnant
When does the estrous cycle begin?
After puberty
What is the estrous cycle?
A series of predictable reproductive events beginning at estrus and ending at the subsequent estrus
What is anestrus?
A period of ceased cyclicity
What are some causes of anestrus? (6)
Pregnancy Lactation Season Poor nutrition Stress Pathology
What is estrus? (2)
A noun
time of sexual receptivity, “heat”
Is estrous a noun or adjective?
Adjective
What does it mean if an animal is polyestrus?
Uniform distribution of estrous cycles throughout the entire year
What animals are polyestrus? (4)
Cattle
Swine
Cats
Rodents
What does it mean if an animal is seasonally polyestrus?
They display clusters of estrous cycles that occur during certain times of the year
What animal(s) are short-day breeders?
Sheep and goats
What animal(s) are long-day breeders?
Mare
What does it mean if an animal is monoestrus?
They have one cycle per year
What animals are monoestrus? (4)
Dog
Wolf
Fox
Bear
What are the phases of the estrous cycle?
Follicular
Luteal
What is the follicular phase?
Period from regression of CL to ovulation
What is the dominant structure in the follicular phase? Hormone?
Follicles
Estrogen
What is the luteal phase?
Period from ovulation to CL regression
What is the dominant structure in the luteal phase? Hormone?
Corpus luteum
Progesterone
How much of the cycle is in the luteal phase?
80%
What are the stages of the estrous cycle?
Proestrus
Estrus
Metestrus
Diestrus
What is the main event of proestrus?
Formation of ovulatory follicles and estradiol secretion
How long does proestrus last?
From CL regression to estrus
2 to 5 days
What does LH and FSH cause in proestrus?
Transition from progesterone dominance to estradiol dominance
What is the main event of estrus?
Sexual receptivity and peak estradiol secretion
What is the dominant hormone of estrus?
Estradiol
How long is estrus?
Ranges from hours to days
What is the main event of metestrus?
CL formation and the beginning of progesterone secretion
When does metestrus occur?
From ovulation to the formation of CL
What are the levels of E2 and P4 like during metestrus?
Low
How long is metestrus?
2 to 5 days
What is the main event of diestrus?
Sustained luteal secretion of progesterone
How long does diestrus last?
10 to 14 days
What is the shortest stage of the estrous cycle?
Estrus
What is the longest stage of the estrous cycle?
Diestrus
What is the reproductive classification of a cow?
Polyestrus
What is the mean length of estrous in a cow?
21 days
What is the mean length of estrus in a cow?
15 hours
What is the time from onset of estrus to ovulation in a cow?
24-32 hours
What is the time from LH surge to ovulation in a cow?
28 hours
What is the reproductive classification of a ewe?
Seasonally polyestrus (short day breeders)
What is the mean length of estrous in a ewe?
17 days
What is the mean length of estrus in a ewe?
30 hours
What is the time from onset of estrus to ovulation in a ewe?
24-30 hours
What is the time from LH surge to ovulation in a ewe?
26 hours
What is the reproductive classification of a mare?
Seasonally polyestrus (long day breeders)
What is the mean length of estrous in a mare?
21 days
What is the mean length of estrus in a mare?
7 days
What is the time from onset of estrus to ovulation in a mare?
5 days
What is the time from LH surge to ovulation in a mare?
2 days
What is the reproductive classification of a sow?
Polyestrus
What is the mean length of estrous in a sow?
21 days
What is the mean length of estrus in a sow?
50 hours
What is the time from onset of estrus to ovulation in a sow?
36-44 hours
What is the time from LH surge to ovulation in a sow?
40 hours
What are the stages of estrous in a dog?
Anestrus
Proestrus
Estrus
Diestrus
What is superfecundation?
Multiple oocytes ovulated over time, so multiple sires are possible
What are the stages of estrous in a cat?
Proestrus Estrus Postestrus Diestrus Anestrus
What is an induced ovulator?
Copulation is required for induction of LH surge
What is postestrus?
Occurs when copulation/ovulation did not occur
What does anestrus result from?
Insufficient GnRH release
When does anestrus occur?
During pregnancy and after parturition until uterus involution occurs
What is silent ovulation?
The first ovulation after anestrus is not accompanied by estrus behavior
Why is there no estrus behavior after the first ovulation?
The first CL produces P4 to increase estrogen sensitivity. When the second ovulation produces E2,behavioral estrus is present
How does photoperiod affect reproduction?
When light hits the retina, the secretion of melatonin is inhibited, so short day breeders have an increase of GnRH (cyclicity) and long day breeders have a decrease of GnRH (anestrus)
What is lactation anestrus?
Controlled by suckling. 2 or fewer promotes the return of cyclicly and more than 2 causes anestrus
What is menses?
Sloughing of the endometrium to the exterior
What are the phases of the menstrual cycle?
Proliferative phase
Secretory phase
What is the proliferative phase?
Menses occurs and the endometrium begins to thicken
What is the secretory phase?
P4 increases which causes the endometrium to proliferate and thicken for embryo
Summarize the follicular phase. (4)
Initiated after luteolysis when P4 is reduced
P4 no longer has a neg. feedback on hypothalamus, resulting in increased FSH and LH release
Follicles develop and produce E2, which has a pos. feedback on hypothalamus
Inhibin is released, which suppresses FSH
What are the 4 main events of the follicular phase?
Gonadotropin release from anterior pituitary
Follicular preparation for ovulation
Sexual receptivity
Ovulation
What does the follicular phase consist of?
Proestrus and estrus
What is the hypothalamic nuclei?
Anatomically discrete regions formed by clusters of nerve cell bodies
What are the 4 processes in follicular dynamics?
Recruitment
Selection
Dominance
Atresia
What is atresia?
Irreversible degenerative process
What percentage of follicles of through atresia?
90%
What are follicular waves?
Due to growth in the presence of P4, therefore, will not ovulate and instead go through atresia
What does FSH do for follicles?
Follicle recruitment
What does LH do for follicles?
Follicle development
What does estrogen do? (6)
Increased blood flow Genital swelling Leukocytosis Increased mucosal secretion Initiation of uterine gland growth Elevated myometrial tone
What are the steps to estrogen synthesis? (5)
- LH binds to LH receptors on theca interna
- Causes cholesterol to be converted to testosterone
- Testosterone diffuses out of theca interna and into granulosal cells
- FSH binds to FSH receptors on granulosal cells
- Causes testosterone to be converted to E2
What does ovulation result from?
A cascade of events that begins with an LH surge
What is hyperemia?
Increased blood flow to ovary and dominant follicle
Read through ovulation in chapter 8 notes. Summarize as if needing to write an essay
Read through ovulation in chapter 8 notes. Summarize as if needing to write an essay
What are the 4 phases of oocyte maturation?
Mitotic division of primordial germ cells
Nuclear arrest
Cytoplasmic growth
Resumption of meiosis
When does mitotic division occur?
Prenatally
What does the last mitotic division result in?
Meiotic prophase, which then arrests
What brings the oocyte out of dormancy?
Stimulation from the gonadotropins after puberty
What forms during the formation of zona pellucida? What do they allow?
Junctional complexes
Communication between oocyte and granulosal cells
What mediates oocyte growth?
Granulosal cells
What is the zona synthesized from?
Mucopolysaccharide material from the oocyte
What initiates meiosis?
LH surge
How is the first polar body formed? When?
Chromosomes line up and separate and form first polar body
Just before ovulation
How is the second polar body produced? When?
Second meiotic division
After fertilization
What estrous phases is the luteal phase made up of?
Metestrus and diestrus
When does the corpus hemorrhagicum appear?
After follicular rupture during ovulation
When is the corpus hemorrhagicum observed?
From ovulation until day 1 to 13 of estrous cycle
What happens as luteal tissue increases?
Bloody appearance clears and corpus luteum forms
What is luteinization?
Process whereby cells of ovulatory follicles are transformed into luteal tissue
What is the corpus luteum controlled by?
LH
What are thecal cells considered?
Small luteal cells