Exam 2 Flashcards
What two categories can the nervous system be divided into?
Structural and Functional
The STRUCTURAL organization of the nervous system is broken into the ______ and ______ NS, while the FUNCTIONAL organization is broken into the _____ and _____ NS.
Structural: Central and Peripheral
Functional: Sensory and Motor
The central NS includes the _____ and _____, while the peripheral NS includes the _______, _______, and ______.
- Brain and Spinal Cord
2. Cervical Nerves, Spinal Nerves, and Ganglia
The CNS and PNS perform three general
functions:
- Collecting information: Receptors detect
changes in the internal and external environment; pass the information on to the CNS - Processing and evaluating information: CNS determines the required response
- Responding to information: CNS initiates nerve impulses to effectors to react to changes in the body’s environment
The sensory NS is divided into the _____ and ______, while the motor NS is divided into the ____ and _____.
- Somatic Sensory and Visceral Sensory
2. Somatic Motor and Autonomic Motor
The sensory NS and motor NS are also called the ______ and _____ respectively.
- Afferent NS
2. Efferent NS
Describe the two distinct type of cells within the nervous system:
- Neurons (nerve cells): Electrically excitable cells that initiate, transmit, and receive nerve impulses
- Glial cells: Nonexcitable cells that support and protect the neurons
What is the basic structural unit of the NS?
The Neuron
What are 3 special characteristics of neurons?
– High metabolic rate
– Extreme longevity
– Nonmitotic
What are the 3 main structural regions of the neuron?
- Cell body
- Dendrites
- Axon
______ receive nerve impulses and carry them to the cell body
Dendrites
Neurons without an axon are called _____
Anaxonic
What is the axon hillock?
The region where the axon connects to the cell body
- Axon collaterals:
- Telodendria:
- Synaptic knobs:
- Side branches off the main axon
- Fine terminal extensions at the end of the axon and its collaterals
- Expanded regions at the tip of telodendria
What 3 ways are neurons classified STRUCTURALLY?
- Unipolar: Single, short process that branches like a T
- Bipolar: Two processes, one dendrite and one axon
- Multipolar: Many dendrites and a single axon; most common type of neuron
What 3 ways are neurons classified FUNCTIONALLY?
- Sensory (afferent): Transmit impulses from sensory receptors to the CNS
- Motor (efferent): Transmit impulses from CNS to muscles or glands
- Interneurons: Facilitate communication between sensory and motor neurons
Brain tumors are more likely to be derived
from ______ than neurons, because they are: (2)
- Glial cells
2. Mitotic and more numerous
What are the 4 types of glial cells found in the CNS?
- Astrocytes
- Ependymal cells
- Microglial cells
- Oligodendrocytes
The most common and least common types of glial cells are _____ and _____ respectively.
- Astrocytes
2. Microglia
What are the 6 functions of astrocytes?
- Helping form the blood-brain barrier (BBB)
- Regulating tissue fluid composition
- Helping regulate synaptic transmission
- Forming a structural network
- Replacing damaged neurons
- Assisting neuronal development
Astrocytes are ______ cells with ________. They are in contact with _______.
- Large
- Numerous Processes
- Neurons and Capillaries
Ependymal cells are _________ cells that line the ________ and the _____________.
- Ciliated cuboidal epithelial
- Ventricles of the brain
- Central canal of the spinal cord
Ependymal cells not only ________, but also ______.
- Produce the CSF
2. Form the choroid plexus
Microglia are _____ cells that _______________, specifically by ____________.
- Small
- Wander through the CNS and exhibit phagocytic activity
- Removing cellular debris from dead or dying cells
Oligodendrocytes are associated with _________. These cells ___________, and they ____________, which is ________.
- CNS axons ONLY
- Wrap themselves around axons
- Produce myelin
- An electrical insulator
Two types of glial cells are found in the PNS:
- Satellite cells
2. Neurolemmocytes
Satellite cells are _____ cells, arranged ______________.
- Flattened
2. Around neuronal cell bodies in ganglia
Neurolemmocytes, also called _______, are associated with __________. They produce ________, and have the same structure and function as ______.
- Schwann Cells
- PNS axons ONLY
- Myelin
- Oligodendrocytes
What is myelination and what does it do?
The process of wrapping a myelin sheath around an axon, it insulates the axon and allows for better conduction of action potentials
Damaged axons can regenerate if ________ and _______.
- The cell body is intact
2. A critical amount of neurilemma remains
Axon regeneration depends on the _______ and _____ of the damage.
- Extent
2. Site
What are the 5 steps of Wallerian Degeneration?
- Trauma Severs Axon
- The proximal portion seals off and swells, while the distal portion and myelin sheath disintegrate but the neurilemma survives.
- The neurilemma and endoneurium form a regeneration tube
- The axon regenerates and remyelination occurs
- Innervation to the effector is restored
What is a nerve?
A cable-like bundle of parallel axons
Describe the 3 connective tissue wrappings of each nerve?
- Endoneurium: Around each axon
- Perineurium: Around individual fascicles
- Epineurium: Around the entire nerve
What are synapses?
Specialized junctions between one axon and another neuron, muscle cell, or gland cell
A typical synapse consists of what 3 things?
- Presynaptic neuron
- Postsynaptic neuron
- Synaptic cleft
Neurons are grouped into patterns called _________
Neuronal Pools
Neuronal pools are defined based on _______, specifically in 4 ways:
Defined by FUNCTION: – Converging – Diverging – Reverberating – Parallel-after-discharge
Nervous system development begins during ________ and is derived from the _______.
- Third week of Development
2. Ectoderm
Thickened ectoderm is called the ________.
Neural Plate
Cells of the neural plate are called _____________.
Neuroectoderm
What are the 4 major regions of the brain?
- Cerebrum
- Diencephalon
- Brain Stem
- Cerebellum
______ is to Anterior, as ______ is to Posterior
- Rostral
2. Caudal
Raised bumps or ridges of the brain are called ______, while the grooves in between them are called ______.
- Gyri
2. Sulci
What are the 3 primary brain vesicles by the THIRD week of development?
- Prosencephalon (forebrain)
- Mesencephalon (midbrain)
- Rhombencephalon (hindbrain)
By the FIFTH week of development, what are the 5 brain vesicles?
- Telencephalon (From PROS)
- Diencephalon (From PROS)
- Mesencephalon
- Metencephalon (From RHOM)
- Myelencephalon (From RHOM)
The Telencephalon forms the _________
Cerebrum
The Diencephalon forms the ______, _____, and _______.
Thalamus
Hypothalamus
Epithalamus
The Metencephalon forms the ______ and _______.
Pons and Cerebellum
The Myelencephalon forms the _________.
Medulla Oblongata
Gray Matter (3):
- Houses motor neuron and interneuron cell bodies, dendrites, telodendria, unmyelinated axons
- Forms the cortex, which covers the surface of most of the adult brain
- Forms discrete internal clusters called cerebral nuclei
White Matter (2):
- Made up of myelinated axons
- Deep to the gray matter of the cortex
What 4 structures protect the brain?
- Bony Cranium
- Blood-brain barrier
- CSF
- Protective connective tissue (meninges)
What are the 3 Cranial Meninges (layers of protective tissue)?
- Pia Mater
- Arachnoid Mater
- Dura Mater
What are the 4 functions of the cranial meninges?
–Separate soft tissue of the brain from bones of cranium
–Enclose and protect blood vessels that supply the brain
–Contain and circulate cerebrospinal fluid
–Form some of the veins that drain blood from the brain
What is the function of the cranial dural septa and what are the names of the 4 of them? (and what do each of them separate)
- They partition parts of the brain to provide stabilization and support
1. Falx Cerebri (Left and Right Cerebral Hemispheres)
2. Tentorium Cerebelli (Cerebrum and Cerebellum)
3. Falx Cerebelli (Left and Right Cerebellar Hemispheres)
4. Diaphragma Celae (Pituitary and Hypothalamus)
The dural venous sinuses run within _________. What are the 4 dural sinuses?
- The margins of the dural septa
1. Superior Sagittal sinus (Sup. Falx Cerebri)
2. Inferior Sagittal Sinus (Inf. Falx Cerebri)
3. Transverse Sinuses (Tentorium Cerebelli)
4. Occipital Sinus (Falx Cerebelli)
________ are cavities within the brain that contain Cerebral Spinal Fluid.
Ventricles
What are the 4 ventricles of the brain?
- Lateral Ventricles (Right and Left CEREBRUM)
- Third ventricle (Diencephalon)
- Fourth Ventricle (Between Pons and Cerebellum)
What separates the two lateral ventricles?
The Septum Pellucidum
Cerebrospinal fluid (CSF) is a clear, colorless liquid that circulates in the _______ and _________.
- Ventricles
2. Subarachnoid Space
What are the 3 main functions of CSF?
- Buoyancy: Brain floats in CSF
- Protection: CSF provides liquid cushion
- Environmental stability: CSF transports nutrients and removes waste from brain
Describe the 5 steps in the production and circulation of CSF:
- CSF is produced in the choroid plexus in the ventricles
- CSF flows from the 3rd ventricle in to the 4th ventricle via the cerebral aqueduct
- CSF then flows into the subarachnoid space by passing through the paired lateral apertures or the single median aperture, THEN into the central canal of the spinal cord
- As CSF flows through the subarachnoid space, it removes waste products and provides buoyancy to support the brain
- EXCESS CSF flows into arachnoid villi, THEN drains into the dural sinuses. The greater pressure on the CSF in the subarachnoid space ensures that the CSF moves into the sinuses without permitting venous blood to enter the subarachnoid space
____________ regulates what substances can enter interstitial fluid of brain
The Blood Brain Barrier
The two main structures that contribute to the BBB are ________ and _______.
- Capillary endothelial cells
2. Astrocyte perivascular feet
In what 3 locations of the CNS is the BBB missing or reduced?
- Choroid Plexus
- Hypothalamus
- Pineal gland
The ________ is the location of conscious thought processes and origin of intellectual functions. For this purpose, it contains ___________ for complex analytical and integrative functions.
- Cerebrum
2. A large number of neurons
Describe the 3 regions of the Cerebrum: (From outer to inner)
- Cortex (Outer Gray Matter)
- Inner White Matter
- Cerebral Nuclei (Deep Gray Matter)