Exam 1 Flashcards
Chondroblasts:
Chondrocytes:
- Produce Matrix for cartilage (immature cells)
2. (mature) Cells surrounded by matrix in spaces called lacunae
Interstitial Growth:
Appositional Growth:
- From within the cartilage
2. Along the cartilage periphery
3 types of cartilage:
Hyaline: Articular surfaces and nose
Fibrocartilage: Vertebral processes, pubic symphysis
Elastic Cartilage: Pinna of the ear
4 functions of bone:
- Support/Protection
- Hemopoiesis
- Movement
- Storage of mineral and energy reserves
What is articular cartilage?
A thin layer of hyaline cartilage at articulations to reduce friction
What are the 4 types of bones
Long bones
Short bones
Irregular bones
Flat bones
The ____ of a bone is the attachment sites for ligaments and tendons.
Epiphysis
The metaphysis, between the epiphysis and diaphysis, contains the _______.
Epiphyseal growth plate
What is the medullary cavity?
Hollow, cylindrical space in diaphysis that contains yellow bone marrow.
Osteoblasts:
Osteoclasts:
- Lay down matrix for new bone
2. Nuclear cells that dissolve bone matrix and release calcium
The _____ covers external surfaces of bone and is anchored by ______ in the bone matrix.
- Periosteum
2. Perforating Fibers
Osteoprogenitor cells:
Produce more osteoblasts or stem cells
Osteocytes:
Maintain bone matrix and detect mechanical stress
Spongy bone is made up of an open lattice of narrow plates called ______
Trabeculae
Canaliculi:
Small passageways that allow osteocytes to pass through them and communicate.
Osteon:
Mature functional unit of compact bone
Epidermal Layer (3):
- Avascular
- Made up of keratinized stratified squamous epithelium
- Has 5 layers
Stratum Basale (5):
- Single layer of mitotic cells
- Adjacent to the dermis
- Keratinocytes (produce keratin/waterproof skin)
- Melanocytes (produce melanin for pigment)
- Tactile cells (sensitive to touch)
Stratum Spinosum (3):
- Many layers thick
- S. Basale daughter cells differentiate into highly specialized non-dividing keratinocytes
- Contains epidermal dendritic cells (Immune defense and phagocytosis)
Stratum Granulosum (3):
- 3-5 layers of keratinocytes
- Fully keratinized cells are dead
- Forms epidermal water barrier
Stratum Lucidum (2):
- Thin, translucent, 2-3 layers thick
- Cells lack organelles, filled with eleidin-intermediate product of keratin maturation
Stratum Corneum (3):
- Most superficial layer
- 23 layers thick
- Made up of dead keratinocytes
Thick vs. Thin Skin (2):
- Thick skin contains all 5 epidermal layers
- Thin skin doesn’t contain stratum lucidum
Dermis is composed of ________
Areolar and dense irregular connective tissue
2 layers of the Dermis:
Papillary and Reticular
Papillary layer (3):
- Superficial (next to epidermis)
- Dermal papillae and epidermal ridges interlock- Increases S.A. between dermis and epidermis
- Dermal papillae contain capillaries to supply nutrients
Reticular Layer (3):
- Deeper/Thicker layer
- Large bundles of collagen, blood vessels, glands, hair follicles and nerves
- Collagen fibers connect dermis to hypodermis
3 reasons Dermis contains nerves:
- Tactile Receptors
- Controls blood flow
- Controls glandular secretions
2 reasons Dermis contains blood vessels:
- Supplies nutrients and helps regulate body temperature
- Vasodilation and Vasoconstriction
What is the significance of the Sternoclavicular Joint?
It is the only connection between the upper extremities and the axial skeleton.
What is meant by “gliding” of bone?
Articular surfaces move, but angle of bones stays the same.
Where does bone gliding occur?
Plane joints
i.e. Carpals and Tarsals
What are the 6 types of synovial joints?
Plane Hinge Pivot Condylar Ball and Socket Saddle
What are Tendon Sheaths?
Elongated bursae around tendons that restrict movement
What type of cells have an apical and basal surface?
Epithelial
Which type of tissue is avascular?
Epithelial
What is mesenchyme?
The source of all adult connective tissue
What is Simple epithelium?
A single layer of cells with all cells having an apical surface and attached to the basement membrane
What is Stratified epithelium?
Two or more layers of cells; not all cells have an apical surface nor do all cells attach to the basement membrane
What is Pseudostratified epithelium?
Cell nuclei give the appearance of a multilayered epithelium, but not all cells reach the apical surface
What makes fibrocartilage so strong?
Densely interwoven collagen fibers
What is the nail matrix?
An extension of the stratum corneum. Thickened growing part of the nail bed.
What is the nail plate composed of? (3)
A white, free edge of the nail
A pinkish nail body
A nail root that is covered by the skin