Exam 2 Flashcards
Functions of bone and the skeletal system
- Support
- Protection
- Assistance in Movement
- Blood Cell Formation
- Mineral Storage
- Triglyceride Storage
Bone Cell Types
Osteocytes
Osteoblasts
Osteoclasts
Osteocytes
A bone cell responsible for the maintenance and turnover of the mineral content of the surrounding bone
Osteoblasts
A cell that produces the fibers and matrix of the bone
Osteoclasts
A cell that dissolves the fibers and matrix of the bone
Compact bone
Dense bone that contains parallel osteons
Location of Compact Bone
Outer shell of all bone and the shafts in long bones
Structure of Compact Bone
The osteocytes are arranged in concentric layers around a central canal.
The lamellae form a series of nested cylinders around the central canal.
Spongy - Cancellous Bone
Composed of a network of bony struts
Location of Spongy Bone
Found in the end of long bones, and in the bones of the pelvic, ribs, vertebrae, and the skull.
Structure of Spongy Bone
Lamellae are not arranged in osteons. The matrix forms a meshwork of supporting bundles of fibers called trabeculae. These thin trabeculae branch, creating an open network.
There are no capillaries or venules in the matrix of spongy bone.
Classification of Bones
- Long Bones
- Short Bones
- Flat Bones
- Irregular Bones
- Sesamoid Bones
- Sutural Bones (Wormian)
Primary Center of Ossification
Occurs in the middle of diaphysis (shaft)
Secondary Center of Ossification
Occurs in each epiphysis of long bone.
Epiphysis
The head of a long bone
Consists largely of spongy bone
Diaphysis
The shaft of a long bone
Consists of a layer of compact bone
Epiphyseal Plate
The cartilaginous region between the epiphysis and diaphysis of a growing bone
Periosteum
A membrane with a fibrous outer layer and a cellular inner layer.
- Isolates bone from surrounding tissues
- Provides a route for the blood vessels and nerves
- Takes part in bone growth and repair
Endosteum
An incomplete cellular lining on the inner (medullary) surface of bones
This layer is active during bone growth, repair, and remodeling.
Perichondrium
The layer that surrounds a cartilage, consisting of an outer fibrous region and an inner cellular region.
Intramembranous Ossification
Bone develops directly from mesenchyme or fibrous connective tissue
Endochondral Ossification
Bone tissue replaces existing cartilage
During development, most bones originate as hyaline cartilages that are miniature models of the corresponding bones of the adult skeleton. These cartilage models are gradually replaced by bone through this process.
Types of Bones
Compact and Spongy
Haversian canal
Contains one or more blood vessels (normally a capillary and a very small vein) tha carry blood to and from the osteon
Generally run parallel to the surface of the bone
Sutural Bones
Small, flat, oddly shaped bones found between the flat bones of the skull.
Irregular Bones
Complex shapes with short, flat, notched, or ridged surfaces.
Examples: Vertebrae, Pelvic Bones, some Skull Bones
Short Bones
Small, boxlike in appearance.
Examples: carpal bones and tarsal bones.
Flat Bones
Have thin, parallel surfaces
Examples: Form the roof of the skull, the sternum, the ribs, and the scapulae.
Long Bones
Relatively long and slender
Examples: located in the arm, forearm, thigh and leg, palms, soles, fingers, and toes.
Largest long bone - Femur
Sesamoid Bones
Usually small, round, and flat.
Example: Patella
Osteons
The basic histological unit of compact bone, consisting of osteocytes organized around a central canal and separated by concentric lamellae
Lamellae
Rings of matrix that surround the central canal.
Ossification
The formation of bone, osteogenesis
Metaphysis
Connecting portion of epiphysis and diaphysis; narrow zone
Calcification
Deposition of calcium salts
Appositional Growth
Process of which the cells of the inner layer of the periosteum differentiate into osteoblasts and deposit superficial layers of bone matrix. Eventually, these osteoblasts become surrounded by matrix and differentiate into osteocytes.
This is the process in which the developing bone increases in diameter.
Increasing the Length of a Developing Long Bone
On the diaphyseal (shaft) side of the metaphysis, osteoblasts continually invade the cartilage and replace it with bone, while on the epiphyseal side, new cartilage is produced at the same rate.
The situation is like a pair of
joggers, one in front of the other. As long as they are running at the same speed, they can run for miles without colliding.
Bone Remodeling
Continuously recycles and renews the organic and mineral components of the bone matrix.
Bone remodeling goes on throughout life, as part of normal bone maintenance.
Calcitrol
Primary Source: Kidney
Promotes calcium and phosphate ion absorption along the digestive tract.
Growth hormone
Primary Source: Pituitary Gland
Stimulates osteoblast activity and the synthesis of bone matrix.
Thyroxine
Primary Source: Thyroid gland
With growth hormone, stimulates osteoblast activity and the synthesis of bone matrix.
Sex Hormones
Primary Source: Ovaries and Testes
Stimulate osteoblast activity and the synthesis of bone matrix; estrogens stimulate epiphyseal closure earlier than androgens.
Parathyroid Hormone
Primary Source: Parathyroid glands
Stimulates osteoclast activity; increases blood calcium ion concentrations
Calcitonin
Primary Source: Thyroid gland
Inhibits osteoclast activity; promotes calcium loss by kidneys; decreases blood calcium ion concentrations.
Fracture
A break or crack in a bone.
Paget’s Disease
A chronic disorder that can result in enlarged
and misshapen bones due to abnormal bone destruction and
regrowth
Axial Skeleton
80 Bones; Forms the longitudinal axis of the body; 40% of the bones in the human body
Skull - 8 Cranial, 14 Facial
Bones associated with the Skull - 6 Auditory ossicles and the Hyoid
Vertebral Column - 24 Vertebrae, Sacrum, Coccyx
Thoracic Cage - Sternum, 24 Ribs
Primary Functions of Axial Skeleton
Provides a framework that supports and protects the brain, spinal cord, and the thoracic and abdominal regions.
Also provides an extensive surface area for the attachment of muscles that (1) adjust the positions of the head, neck, trunk; (2) perform respiratory movements; and (3) stabilize or position parts of the appendicular skeleton.
Suture
A synarthrotic joint located only between the bones of the skull.
Does not move
Types of Sutures
- Lamboid Suture
- Coronal Suture
- Sagittal Suture
- Squamous Suture
Lamboid Suture
Connects the occipital bone with the two parietal bones
Coronal Suture
Attaches the frontal bone to the parietal bones of either side