Exam 2 Flashcards

0
Q

!!!!! Definitions
Reactions covalently link monomers together to form polymers are called _______, where as reactions that break polymers into monomers are _____ reactions.

A

Dehydration

Hydrolysis

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1
Q

Functional groups:
NH2
PO4
CH3

A

NH2 amino group
PO4 phosphate group
CH3 methyl group (non polar)

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2
Q

!!!!!! 2 storage polysaccharides

A

-starch
-glycogen
-cellulose
(All polymers of glucose)

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3
Q

3 general classes of lipids:

A
  • triglycerides
  • phospholipids
  • steroid lipids
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4
Q

3 functions of proteins:

A
  • energy storage
  • structure
  • generate movement (motor proteins)
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5
Q

!!!!! 2 types of bonds/attractions that hold side chains

(R groups) of amino acids together to contribute to tertiary structure of polypeptide:

A
  • hydrogen bonds

- disulfide bridges

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6
Q

3 components of a nucleotide of a DNA:

A
  • 5-carbon sugar (pentose)
  • nitrogenous base
  • phosphate group
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7
Q

Names of the monomers that make up these polymers:
nucleic acids
Polypeptides
Polysaccharides

A

Nucleotides
Amino acids
Monosaccharide

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8
Q

2 ways nucleotide in DNA differs from nucleotide in a RNA

A
  • sugar present

- uracil and thymine

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9
Q

Functional groups on 2 ends of polynucleotide

chain

A

Hydroxyll 3’

Phosphate 5’

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10
Q

!!!! DNA polymerase I

A

Removes nucleotides from RNA primer.

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11
Q

!!! Topoisomerase

A

Prevents over winding

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12
Q

!!!!! DNA polymerase II

A

Adds nucleotides to leading strand of DNA

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13
Q

!!!! Okazaki fragment

A

Has a primer and segment of DNA on lagging strand of DNA

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14
Q

!!!!! Ligase

A

Makes final phosphodiester bond between 2 Okazaki fragments

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15
Q

!!!!! Primase

A

Lays down short sequence of RNA nucleotides before DNA Polymerase III can begin replication

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16
Q

!!!! Helicase

A

Breaks hydrogen bonds between complimentary bases at replication fork

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17
Q

!!!!! Origin

A

Sequence of DNA nucleotides where replication begins

18
Q

!!!!!! Single-stranded binding proteins

A

Binds to nucleotide chains of DNA and prevents reformation of hydrogen bonds between complimentary bases.

19
Q

!!!!!! Phosphodiester bonds

A

Holds together adjacent nucleotides within a polynucleotide chain

20
Q

!!!!!!Who found that DNA replicates semiconservatively?

A

Meselson and Stahl

21
Q

!!!!! Who published the 3-dimensional structure of DNA?

A

Watson and crick

22
Q

!!!!! Who found that DNA was the genetic material of T2 phage?

A

Hershey and chase

23
Q

!!!!! Who found that the amount of adenine equals the amount of thymine and the amount of guanine equals the amount of cytosine, in any sample of DNA?

24
!!!!! Who found that DNA transferred avirulent bacteria into virulent bacteria?
Avery, Macleod, and McCarty
25
!!!!! Who found x-Ray diffraction indicated DNA was double stranded and uniform width?
Franklin
26
!!!!! Who found that rough streptococcus picked up something from dead smooth streptococcus that transformed them into the smooth type?
Griffith
27
Disaccharides:
Sucrose Lactose Maltose
28
Monosaccharide
Ribose
29
Hydrogen bonds along N-C-C backbone of polypeptide is important for what protein structure?
Secondary
30
What functional group isn't attached to central carbon of an amino acid?
Phosphate group
31
Side chains (R groups) of polypeptide are important for what level of protein structure?
Tertiary
32
Protein denaturing involves:
Breaking hydrogen bonds along N-C-C backbone.
33
Functional groups on ends of polypeptide chain
Amino | Carboxyl
34
DNA complimentary hydrogen bonding occurs between:
One pyrimidine | One purine
35
!!!!!! What bond holds amino acids together in a polypeptide?
Peptide bond
36
What bond holds monosaccharides together in a polysaccharide?
Glycosidic linkage
37
What bond holds complimentary bases together in a DNA molecule?
Hydrogen bond
38
!!!!!! Triglycerides
Formed by bonding glycerol (3C molecule with hydroxyl group to each C) to 3 fatty acids
39
!!!!!! Primary structure level
Amino acid sequence from beginning to end. | -carry info for production of polypeptides with specific amino acid sequences
40
!!!! Secondary structure
Folding structure. | Causes protein to fold more compactly and in any shape.
41
!!!! Tertiary structure
Side chains of amino acids interact and polypeptide folds and refolds ----> 3D
42
!!!! Quaternary structure
2+ polypeptide chains that assembles with tertiary structure.
43
!!!! Factors that influence protein structure
H bonds | Ionic bonds