Exam 2 Flashcards
what ions are higher in concentration intracellularly?
potassium, negatively charged organic molecules
what ions are higher in concentration extracellularly?
sodium
what is the charge of a neuron?
none, they are electrically neutral
depolarization
potential difference is reduced. intracellular environment becomes more positive
repolarization
return to resting membrane potential. intracellular become more negative
hyperpolarization
intracellular more negative than resting membrane potential
what is resting membrane potential?
-55mV
what is another name for resting membrane potential?
threshold value
what causes an action potential?
the influx of sodium
what type of transport does depolarization and repolarization occur via?
diffusion
what occurs after action potential?
Na+/K+ pump (ATPase pump)
what is the most positive the amplitude during depolarization will get?
30-40mV
absolute refractory period
axon membrane is incapable of producing another action potential
relative refractory period
axon membrane can produce another action potential, but requires stronger stimulus
what channel opens during absolute refractory period?
Na+
what channel opens during relative refractory period?
K+
low frequency action potential will yield what kind of stimulus?
a weaker stimulus
high frequency action potential will yield what kind of stimulus?
a stronger stimulus
recruitment
when stronger stimuli activate more axons with a higher threshold
saltatory conduction
the process where electrical impulses jump between nodes of ranvier along a myelinated axon. fast rate of conduction
synapse
functional connection between a neuron and another neuron or effector cell
electrical synapse
broad effect. impulses can be regenerated w/o interruption in adjacent cells
electrical synapse gap junctions
adjacent cells electrically coupled through a channel
chemical synapse
specific effect. neurotransmitters are released within axon causing synaptic vesicles to fuse w/axon membrane + release NTs to cleft by exocytosis
excitatory postsynaptic potential (EPSP)
NT w/excitatory effects
example of an EPSP
glutamate, acetylcholine
inhibitory postsynaptic potential (IPSP)
NT w/inhibitory effects. inhibits reciprocal muscles from firing
example of IPSP
GABA
what electrical effect occurs during EPSP?
depolarization
what electrical effect occurs during IPSP?
hyperpolarization
lateral ventricles
paired c-shaped chambers in each hemisphere
what separates the anterior horns of the lateral ventricles?
the septum pellucidum
what is the roof of the anterior horn of lateral ventricles?
corpus callosum
what is the floor of the anterior horn of lateral ventricles?
superior thalamus + caudate nucleus (basal ganglia)
what is the floor of the inferior horn of the lateral ventricles?
hippocampus
what are the 3 horns in the lateral ventricles?
anterior (frontal), posterior (occipital), + inferior (temporal)
what is the atrium of the lateral ventricles?
triangular cavity where the body, posterior, and inferior horns communicate
what is another name for the atrium?
trigone
what allows communication and flow of CSF between the lateral ventricles and 3rd ventricle?
intraventricular foramen of monro
where is the 3rd ventricle located?
middle space between the thalamus + hypothalamus
superior border of the 3rd ventricle?
fornix
anterior border of the 3rd ventricle?
lamina terminalis + anterior commissure
floor of the 3rd ventricle?
infundibulum + optic chiasm
posterior wall of the 3rd ventricle?
pineal wall
lateral border of the 3rd ventricle?
medial nuclei of thalami
what are the 3rd ventricle recesses?
infundibular, supraoptic, pineal, suprapineal
what connects the 3rd to the 4th ventricle?
cerebral or mesencephalic aqueduct
what is another name for the cerebral aqueduct?
aqueduct of sylvius
what is the inferior portion of the 4th ventricle called?
obex
what does the obex connect?
the central canal of the spinal cord and the 4th ventricle
anterior border of the 4th ventricle?
rhomboid fossa
posterior border of the 4th ventricle?
cerebellar peduncles + superior/inferior medullary velum
lateral walls of the 4th ventricle?
cerebellar peduncles
how does the 4th ventricle communicate with the subarachnoid spaces?
medial foramen of magendie + lateral foramen of luschka
ependyma
thin, neuroepithelial lining of the ventricles and central canal of the spinal cord
choroid plexus
produces CSF + barrier between blood and CSF
function of CSF
provide cushion to protect the brain, drainage of cerebral metabolites, + regulate cerebral blood flow
CSF volume
150mL
CSF components
99.13% water + .87% organic/inorganic substances
flow of CSF
lateral ventricles > interventricular foramen > 3rd ventricle > cerebral aqueduct > 4th ventricle > subarachnoid space > cisterna magna > arachnoid villi > dural venous sinuses
where does CSF drain into?
subarachnoid space
where is the subarachnoid cistern located?
cisterns
compartments within the subarachnoid space where the pia mater + arachnoid membrane are not close
arachnoid villi function
return CSF to venous circulation through the dural venous sinus
dural venous sinuses
large valveless venous channels that drain venous blood from cranial cavity
where are dural venous sinuses located?
periosteal dura + meningeal dura
function of dural venous sinuses
maintain systemic circulation by collectively returning deoxygenated blood from the cranial vault
cerebral + cerebellar veins
cross subdural space to drain into the superior sagittal vein
emissary veins
venous structures that allow communication between intracranial + extracranial vessels
diploic veins
intraosseous venous vessels that drain blood between the inner + outer layer flat bones of the skull
meningeal veins
collect blood from the meninges + drain
arachnoid granulations
CSF returning to the venous circulation