Exam 2 Flashcards
What is bone made of
25% water
25% collagen fibers
50% crystallized mineral salts
Osteoblasts
Bone-building cells
Osteocytes
Mature bone cells
Osteoclasts
Release enzymes that break down bone (resorption)
Bone may be categorized as
compact
spongy
Osteopenia
Low bone mass
Osteoporosis
porous bones
What happens in osteoporosis
Fractures occur easily
More common in women
Treatment of osteoporosis
Antiresorptives
Bisphosphonates (fosomax, actonel, and boniva)
Estrogen replacement therapy (premarin)
What stimulates osteoblastic activity
Estrogen in women
Testosterone in men
Rickets
inadequate calcification of bone. Deficiency of Vitamin D. In children
Osteomalacia
Adult rickets
Vit d deficiency
Osteoarthritis
degeneration of articular cartilage
Osteogenic sarcoma
Bone cancer
usually in teens, occurs when teen grows rapidly
Osteomyelitis
Infection of bone
Vitamin A
Stimulates osteoblast activity
Vit C
needed for synthesis of collagen
Vit D
helps build bone by increasing the absorption of calcium from foods in the gastrointestinal tract into the blood
How many bones in human skeleton
The human skeleton consists of 206 named bones
Fissure
Narrow slit
Foramen (foramina)
opening
Tuberosity
large prominence on a bone
Axial skeleton
Consists of the bones that lie around the longitudinal axis of the human body
Appendicular skeleton
Consists of the bones of the upper and lower limbs, plus the bones that connect the limbs to the axial skeleton
Axial skeleton pic 1
frontal bone
Axial skeleton pic 2
Zygomatic bone
Axial skeleton pic 3
Mandible
Axial skeleton pic 4
Nasal bone
Axial skeleton pic 5
Maxilla
Temporal bones
External auditory meatus (ear canal) is found in the temporal bone
Sphenoid bone
the keystone
Occipital bone
In the back of the skull
Nasal bones
Where glasses sit
Maxillae
Upper jaw
Deficiency in folic acid causes what
Cleft lip and palate
Zygomatic bones
cheek bones
Mandible
The only movable skull bone
The lower jaw
Temporomandibular joint
Temporal bone/mandible
Bruxism, trauma
Fontanels
Soft spot found in infant skull
Important, so as the brain grows, the skull expands
Hyoid bone
In the neck
Rarely fractures
Strangulation will cause fracture of the hyoid bone
Vertebral column
Also called the spine, backbone, or spinal column
Sternum
Breastbone
Consists of the manubrium, body, xiphoid process
How many ribs
12 pairs
Scoliosis
Scoliosis can make the spine look more like the letters “C” or “S”
Kyphosis
Looks like a hunchback
Lordosis
Booty out
Teeth from front to back
Incisor
Cuspid
First Bicuspid
Second bicuspid
First molar
Second molar
Third molar (wisdom teeth)
How many teeth in adults and children
32 in adults including wisdom
20 in children
Amalgam filling
Silver
Composite filling
Tooth colored
Cuspid teeth
Canine
Bicuspid teeth
premolars
Cartoon mouth pic 1
Canine
Cartoon mouth pic 2
molars
cartoon mouth pic 3
premolars
cartoon mouth pic 4
incisors
real mouth pic 1
central incisor
real mouth pic 2
Lateral incisor
real mouth pic 3
Canine
real mouth pic 4
First premolar
real mouth pic 5
2nd premolar
real mouth pic 6
first molar
real mouth pic 7
second molar
real mouth pic 8
third molar (wisdom tooth)
Blood volume in males and females
5-6 and 4-5
Temperature of blood
38 Celsius
100.4 fahrenheit
Blood plasma
Liquid
Blood is what % water
91.5
Formed elements of blood
RBCs
WBCs
Platelets
Type AB blood
AB antigens
Universal recipient
Type O blood
Neither antigen
Universal donor
erythrocytes
RBCs
Carries oxygen to body’s cells
Biconcave disc
Strong, flexible plasma membrane
Lacks nucleus
Leukocytes
WBCs
Fights disease and foreign invaders
Platelets
Aids in blood clotting
Centrifuged blood
RBCs on bottom (45%)
Buffy coat composed of WBCs and plts
Plasma on top (55%)
Hematocrit
the percentage of total blood volume occupied by red blood cells
Satellite droplets
When blood falls from a height, or at a high velocity, it overcomes its natural cohesiveness, and
separates from the main droplet
Spiking patterns
Form around the droplet edges when blood falls onto a less-than-smooth surface
Lines of convergence
two or more blood splatters can pinpoint the location of the blood source
Luminol
Used by CSI to locate traces of blood even after being cleaned or removed
Sprayed throughout the area to look for reactions causing a blue luminescence
LCV
Leuco crystal violet
A chemical process used for blood enhancement
Using this test helps make blood evidence more visible so it can be photographed and analyzed
Male and female chromosomes
XY and XX
How many chromosomes in human body cells
46
What is DNA made of
Two long chains (strands) arranged in a double helix
James Watson and Francis Crick
1953
Founded that the DNA is a double helix
Rosalind Franklin
Used x-ray diffraction
DNA in dividing vs nondividing cells
Tightly coiled (chromosomes) in dividing cells (Condensed)
Loosely coiled (chromatin) in nondividing cells (Diffuse)
Nitrogenous bases DNA
Adenine (A)
Thymine (T)
Cytosine (C)
Guanine (G)
Pentose sugar
in DNA is deoxyribose
What is DNA made of
Nitrogenous bases
Pentose sugar
Phosphate group
DNA in bases pairs
Adenine (A) matches with Thymine (T)
Cytosine (C) matches with Guanine (G)
big to small from gene to cell
Gene is part of DNA
DNA is part of chromosome
chromosome is part of nucleus
nucleus is part of cell
DNA controls production of
proteins
what are proteins
chains of amino acids bonded together
What body cells are dna found in
nucleus of:
WBCs, cheek (buccal) cells, semen, saliva, urine, hair follicle, teeth, bone tissue
Most abundant in buccal cells
DNA from blood comes from WBCs
RBCs have no nuclei so no DNA
Who draws blood
phlebotomist
DNA profiling, fingerprinting, and typing
All the same thing
Refers to the process of identifying an individual based on their unique DNA characteristics
Who invented DNA fingerprinting
Alec Jeffreys at the University of Leicester in 1985
When was Alec Jeffreys knighted
1994
Gel electrophoresis
A technique used to separate DNA fragments
An electrical current is moved through a gel substance, causing molecules to sort by size.
The smaller, lighter molecules will move the farthest on the gel.
After developing, the fragments can be visualized for characterization