EXAM 2 Flashcards
Bipolar 1 is what two things
MDD
Mania
What is mania
Excessive energy/purposeless movement. Restless
What does mania look like in bipolar 1
Little to no sleep
Flight of ideas. Racing thoughts
Reckless behavior with $ and sex
Impulsive (labile mood)
Psychosis (hallucinations/delusions)
Bipolar one is diagnosed how
MDD for 2 weeks
Mania for 1 week
Tx for bipolar
2 things
4 med types
Hospitalization (bipolar 2 doesnt need)
Calm environment
Meds:
-lithium
-anticonvulsants
-antipsychotics
-benzos for sleep
Bipolar 2
What 2 things
Compared to type 1
Has no what vs type 1
4 episodes
MDD
Hypomania (less severe, dont need hospitalization)
Less need for sleep (5-6)
More directed activity
No PSYCHOSIS (hallucinations/delusions)
4 or more episodes in a year= rapid cycling
Bipolar 2 how to diagnose
MDD 2 weeks
Hypomania 4 days
Cyclothymia (2 years needed)
What does thymia mean
What two things it has
What causes a mood episode
Has a strong what component
Thymia=low level/ long lasting
Mild-moderate depression
Hypomania
Stress/sleep precipitate mood episodes
Bipolar has a strong genetic component
Can antidepressants be used to treat bipolar?
Yes with a mood stabilizer to prevent mania/hypomania.
Used very cautiously for pt with bipolar 1
Risk of triggering flipping into hypomania/mania
SSRIs are used on when pt is stabilized bc it can flip them into a manic state
Lithium (ONLY TRUE MOOD STABILIZER)
Narrow therapuetic index
Hard on what two organs
SE
0.6-1.2 is normal
More aggressive tx is 1-1.5
Hard on kidneys and thyroid
SE:
Fine hand tremors
GI distress (nausea)
Thrist
Polyuria
Wt gain
Lethargy
Anticonvulsant meds
Valporic acid
Carbamazepine
Lamotrigine
Valporic acid
SEs
Needs
Get enzymes due to:
Liver
Pancreatitis
GI
Thrombocytopenia
Wt gain
Teratogenic
Need labs monitored
Carbamazepine
Careful with what
SEs
Need what
Careful with heart issues
SEs:
Leukopenia
Thrombocytopenia
SJS
Need labs monitored
Lamotrigine(safest most tolerated)
Risk for what
If miss how many days you have to do what
SEs
Risk for benign rash/SJS
If miss 5 days of meds, need to restart titration
SE:
Tremors
HA
Antipsychotics
1stgen
EPS/NMS
2ndgen
Ziprasidone and lorasidone (take with food)
Queitapine (wt gain/sedation)
Olanzapine (wt gain)
Risperidone (prolactin and breast issues)
Clozapine (agranulocytosis, NEED LABS)
3rdgen
Aripiprazole (akathesia)
Review on pharm
NMS symptoms
BAD FEvER
Labile bp
Led pipe rigidity
EPS
Acute Dystonia
Psudoparkinsons
Akathesia
Tardive dyskinesia (could be irreversible)
Antidote: benzotropine, diphenhydromine
Hypomania vs mania
Mania need a week
Hypomania needs 4 days
Mania: excessive energy/purposeless movement
Restless
Needs hospitalization
Hypomania: less severe.
Dythmia (persistent depressive disorder)
What it looks like
To diagnose
Low mood
Mild-moderate depression (not as severe as MDD)
Long lasting
To diagnose:
Adults - 2 years
Children/adolescents - 1 year
2 or more for the following symptoms:
Appetite change
Sleep change
Low energy
Low self-esteem
Poor concentration
Feelings of hopelessness
Premenstrual dysphoric disorder
Symptoms
Depressed mood
Anxiety
Mood swings
Decreased interest in activities
Improved mood with end of menses
Seasonal affective disorder (SAD)
When, what
Tx
Nov-April
Lower mood
Tx:
Vit d
Light therapy
SSRI
major depressive disorder
Symptoms
Depressed mood / irritable / saddness
Anhedonia (without pleasure)
Isolating
Crying
Numbness
Change in appetite and sleep
Anergia (decreased energy)
Impaired in ADLs
Imparied concentration
Avolition (without motivation)
Anger
Guilt/hopelessness/helplessness (risk for suicide)
Slowed speech
MDD need to be present for how long to diagnose
2 weeks
MDD tx
SSRIs take 4-6 weeks
ECT-induced seizures (need informed consent, NPO @ midnight), can cause memory loss
CBT
Therapeutic communication
ECT is good for what
Acutely suicidal
psychotic depression (depression with psychosis diagnosis)
CBT
Manage distored thoughts
Identify dysfunctional patterns of thinking and behaving
Changing automatic thoughts
SSRIs
Vs
SNRIs
SSRI: takes 4-6 weeks to work
Citalopram, escitalopram, sertraline, fluvoxamine, paroxatine, fluvoxatine
Black box warning: increase energy=suicidal risk
SNRIs:
Venlafaxin, duloxetine, desvenlafaxine
Increase BP, HR
Schizophrenia positive symptoms
Things were adding on that wouldnt normally be there in a normal person
Delusions
Hallucinations
Alterations in speech
Behavior
Schizophrenia delusions
What is it
Donts
Dos
Fixed/false belief
Dont:
Aruge with them
Feed it
Do:
Focus on underlying feeling (anxiety)
Focus on reality/present(hi my name is brendon and i am your nurse and we are here to take care of you)
Schizophrenia hallucinations
Sensory (auditory most common), visual, tactile
Need to know if it is command hallucinations (voices telling them to do something) for safety
Offer your own perception of reality (i understand you see that but i do not)
Schizophrenia altered speech
-Word salad (actual words put together dont make sense)
-Echolalia (pt repeats back after you) (how are you today. Today today today)
-neologism: made up word the pt attaches their own meaning
-flight of ideas
-loose associatation
-clang association (rhyming words)