Exam 2 Flashcards

1
Q

Functions of the lymphatic system include

A

Produce, maintain, and distribute lymphocytes and other lymphoid cells

Return excess fluid to bloodstream

Maintain normal blood volume

Transport hormones, nutrients, and wastes.

Eliminates variations in the composition of interstitial fluid

Transports lipids from the digestive tract

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2
Q

Does lymph rely on a pressure gradient to return to the heart?

A

yes, goes from high to low pressure.

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3
Q

Lymphatic vessels carry what

A

Carry lymph from peripheral tissues to veins in a
one way direction, no loop like blood. We are just taking excess fluid and putting it in the heart.

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4
Q

Primary lymphoid tissues/organs are concerned with

A

forming and maturing lymphocytes

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5
Q

Secondary lymphocytes are concerned with

A

where lymphocytes are activated

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6
Q

Why is the structure of lymphatic capillaries significant?

A

Because it allows for it to take in a lot of fluid to carry back to the heart.

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7
Q

What is problematic about the structure of the lymphatic capillaries?

A

They have no permeability, no basement membrane, and thinner walls.

Lack of selectivity can cause pathogens to get to the heart.

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8
Q

With lymphatic capillaries, there are shingles present. What is the physiology of these shingles?

A

High pressure causes fluid to open endothelial cell and let fluid in if the pressure Is coming from outside. Pressure build up inside endothelium will push the shingles of endothelium on to other endothelium cells.

Characteristic of the closed end nature of the capillary.

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9
Q

Right lymphatic duct concerns

A

1/4 of lymph to the top right portion of the body.
Right side above abdominal and right face.

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10
Q

Left lymphatic duct (thoracic duct) concerns

A

collects blood from 3/4 of the body

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11
Q

Lymphocytes make up what percent of leukocytes

A

20-40%

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12
Q

Lymphocytes are mainly ____

A

stored, not circulating

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13
Q

T cells are reliant on the

A

thymus

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14
Q

B cells are reliant on

A

bone marrow

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15
Q

NK cells

A

Natural killer cells
Can fight against more than one pathogen- they have a very similar development story to T and B cells and that’s why they’re considered lymphocytes.

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16
Q

lymphocytes are dominated by what kind of tissue?

A

connective tissue

17
Q

Lymphoid nodules are made up of

A

areolar tissue with densely packed lymphocytes.

18
Q

Lymphoid nodules are distributed in

A

nasal/oral cavity & pharynx and tonsils

19
Q

Tissues(think intestines)

A

Small intestines - Peyer’s patches
Large intestine - Appendix

20
Q

What lymphoid tissues deal with food that could carry pathogens?

A

MALT(Mucosa Associated Lymphoid Tissues)

21
Q

Germinal center helps with

A

dividing lymphocytes to battle incoming pathogens

22
Q

Are there more afferent vessels than efferent vessels?

A

Yes, because many afferent vessels are bringing in unclean lymph from all parts of the body to clean them of pathogens and only need a single efferent vessel to carry the clean lymph.

23
Q

Pathway of lymph circulation in lymphatic capillaries:

A

Afferent Lymphatics > Subscapsular space (transports fluid) > Cortex (B cells) > Paracortex (T cells) > Medulla (Macrophages, B cells) > Efferent lymphatics

24
Q

What is the significance of the structure of lymphatic organs when compared to the structure of lymphatic tissues?

A

Lymphatic organs have a fibrous capsule with the geminal center and such and lymphatic tissues don’t.

25
Function of lymph nodes
purify lymph before return to venous circulation Remove 99 percent of antigens
26
Antigens released due to infection
Enter lymph and stimulate macrophages and lymphocytes in lymph nodes Are also carried by dendritic cells to lymph nodes
27
Lymphoid tissues and lymph nodes
Monitor peripheral infections Respond before infections reach vial organs.
28
Organs have capsules (structure)- first space you get to is the
the subcapular space.
29
the thymus is located in the
mediastinum
30
T/F, does the thymus atrophy after puberty?
T
31
Structure of the Thymus
Divided into two thyme lobs Septa divide lobs into smaller lobules There will not be any b lymphocytes Why?: Think about whether or not it’s a primary or secondary structure
32
Function of the Thymus
Learning which antigen they can fight against. Produces T cells. Diminishes effectiveness of immune system
33
Functions of the spleen:
Removal of abnormal blood cells and other blood components by phagocytosis Storage of iron recycled from red blood cells Store some of the heme in the spleen. Initiation of immune response by B and T cells. Large collection of lymphocytes. In response to antigens in circulating blood. Synosoid capillaries- Largest collection of lymphoid cells in the body- at risk for old RBCs floating around- at risk for infections. White Pulp: contains lymphocytes Red Pulp: RBCs/Macrophages
34
The spleen needs a lot of blood because it's a
vascular organ
35
If the spleen is affected, what will happen to RBCs?
there will be a circulation of old RBCs.
36
Primary lymphoid organs
bone marrow, thymus
37
Secondary lymphoid organs:
spleen, lymph nodes, tonsils, MALT, small and large intestines.
38
The intertwining of veins and arteries with lymphatic capillaries is allows for
Lymphatic capillaries to pick up fluid from the bloodstream, clean it up, and bring it back to the heart for circulation.