Exam 2 Flashcards

1
Q

Bioenergetics (Metabolism)

A

chemical process of converting food into energy

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2
Q

catabolic

A

breaking down larger molecules into smaller molecules

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3
Q

anabolic

A

building smaller molecules into larger molecules

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4
Q

glycogen

A

storage form of glucose in animals (stored in muscle and liver)

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5
Q

glycogenesis

A

formation of glycogen from glucose

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6
Q

glycogenolysis

A

breaking down glycogen into glucose

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7
Q

ATP-Pcr cycle

A

CK (creatine kinase) controls rate of ATP production (negative feedback system)

when ATP levels drop ADP and CK activity increases

when ATP levels increase CK activity decreases

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8
Q

ATP-Pcr system

A

stored ATP (2-3 seconds of max effort)

phosphocreatine is broken down by creatine kinase, which can be used to create ATP

last 30 sec (short, intense sprints/vertical jumps)

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9
Q

role of glucose in glycolysis

A

glucose transforms to lactate when limited amounts of oxygen are available

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10
Q

the role of ATP-Pcr on fatigue and how it relates to intensity and time of exercise

A

breakdown of ATP & PCR not primary cause of decreased muscle force and fatigue, breakdown of PC occurs, aerobic recovery period is necessary to provide energy to reform PC

high intensity bouts are accompanied by lower-intensity recovery periods

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11
Q

how does exercise alter these systems (ATP-Pcr)

A

increases in major enzymes (CK) would result in faster regeneration of ATP

in anaerobic training, some studies demonstrate increased intramuscular concentrations of ATP and PC at rest

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12
Q

what is lactate and how is it produced?

A

when cells break down carbs for energy, remaining compound bind with positively charged sodium ion or potassium ion to form the acid salt lactate

forms during anaerobic glycolysis

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13
Q

Basal Metabolic Rate (BMR) and what contributes to it?

A

minimum # of calories required for basic function at rest

body size (larger adults have more metabolizing tissue and larger BMR), amount of lean muscle tissue, amount of body fat

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14
Q

Resting Metabolic Rate (RMR) and what contributes to it?

A

of calories that your body burns while its at rest

physical activity, increased metabolic rate during exercise partially carries over when exercise stops

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15
Q

glycolysis (aerobic vs anaerobic)

A

Aerobic: slow, results in pyruvate-to-acetyly CoA-to-citric acid cycle (krebs) and electron transport of the remaining energy within original glucose molecule 2 ATP

Anaerobic: pyruvate-to-lactate formation with the release of about 5% of energy within the original glucose molecule, more ATP production 2 ATP, 3 ATP from glycogen

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16
Q

krebs cycle

A

pyruvate in the absence of oxygen converted to lactate

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17
Q

oxidative phosphorylation

A

ETC, breaking down hydrogens to produce huge amounts of ATP

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18
Q

fate of pyruvate during aerobic metabolism

A

pyruvate is transported to mitochondria. inside mitochondria pyruvate undergoes oxidative decarboxylation and produces acetyl CoA

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19
Q

fate of pyruvate during anaerobic metabolism

A

pyruvate undergoes reduction which produces lactate

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20
Q

EPOC

A

post exercise oxygen consumption

amount of oxygen required to restore body to its normal resting level of metabolic functions (homeostasis)

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21
Q

oxygen deficit

A

difference between total oxygen consumed during exercise and total that would have been consumed had steady-rate oxygen uptake been achieved at the start of exercise

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22
Q

rate limiting factors

A

fluid loss/electrolyte depletion and maintaining adequate reserves of liver glycogen for CNS function & muscle glycogen to power exercise

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23
Q

why is fat oxidation increased walking vs cycling?

A

when walking, your weight is supported o your ankles activating more muscles. more muscles activated = the greater fat oxidation.

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24
Q

why might femals have an enhanced fat oxidation vs males?

A

females typically have more adipose tissue, more tissue you have, more you can burn

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25
Q

what is the respiratory quotient?

A

carbs, fats, and proteins require different amounts of O2 for complete oxidation. based on the byproducts of metabolism (CO2/H2O)

RQ = CO2 produced/O2 consumed

26
Q

respiratory quotient (RQ) carbs

A

1.0 (6 CO2/6 O2)

27
Q

respiratory quotient (RQ) protein

A

0.83 - 0.85 (63 CO2/77 O2)

28
Q

respiratory quotient (RQ) fat

A

0.7 (16 CO2/23 O2)

29
Q

lactate threshold

A

point at which, during incremental exercise, lactate builds up in the blood system, at a level that is higher than resting values

30
Q

how does exercise alter lactate threshold?

A

increased ability to metabolize lipid

increase enzymes of the Krebs cycle and ETC

increased capillary density and #

31
Q

triglyceride

A

stored form of fat

32
Q

what does the body emphasize for short, high intensity activities?

A

anaerobic metabolism

first 30 seconds: ATP-PC System
30 sec - 3 minutes: Glycolysis

33
Q

what does the body emphasize for activities for longer than 3 minutes?

A

aerobic metabolism

34
Q

aerobic pathways

A

more efficient production of energy from a given substrate like glucose

can use carbs and fats and proteins (when necessary)

primary source of energy at rest and extended, low intensity activities

35
Q

ETC

A

hydrogen channels in the membrane allow hydrogen ions to flow down their concentration gradient, which activates ATP synthase

36
Q

lipid catabolism

A

stored fat serves as most plentiful source of potential energy

fat becomes primary energy fuel for exercise/recovery when intense, long-durations exercise depletes blood glucose and muscle glycogen

4x ATP produced than glucose

37
Q

lipid mobilization

A

hormone sensitive lipase stimulates triacylglcerol (TAG) breakdown into its glycerol (1) & fatty acid components (3)

energy releases when TAG stored in muscle fibers degrades to glycerol and fatty acids

38
Q

beta oxidation

A

process of converting FFAs to acetyl CoA before entering Krebs cycle

requires up-front expenditure of 2 ATP

39
Q

lipid oxidation

A

acetyl-CoA enters Krebs cycle

40
Q

endocrine effects (aerobic metabolism)

A

epinephrine, norepinephrine, glucagon, and growth hormone increase lipase activation and subsequent lipolysis and FFA mobilization from adipose tissue

hormonal release triggered by exercise stimulates adipose tissue lipolysis to further augment FFA delivery to active muscle

41
Q

amino acids metabolism typically smaller except

A

extreme dieting increases protein breakdown

high protein diets can increase use of proteins for energy

long-term endurance activity activates proteases

42
Q

maximal exercise

A

VO2 max occurs when oxygen uptake plateaus or increases only slightly with additional increases in exercise intensity

43
Q

lipid & glucose interaction (insulin)

A

insulin inhibits hormone-sensitive lipase, decrease free fatty acids and transports glucose into skeletal muscles

ingesting high-carb meal/drink decreases triglyceride metabolism and increases carb metabolism

44
Q

“crossover” effect

A

describes the shift from fat to CHO metabolism as exercise intensity increases (activating fast muscle fibers and increasing blood levels of epinephrine)

45
Q

low intensity exercise

A

<30% VO2 max

fats are primary fuel during prolonged low intensity exercise

46
Q

high intensity exercise

A

> 70% VO2 max

carbohydrates are primary fuel

47
Q

blood lactate threshold

A

occurs when muscle cells can neither meet energy demands aerobically nor oxidize lactate at its rate of formation

occurs at higher % of trained aerobic capacity compared to untrained

48
Q

fast-twitch (type II) role

A

rapid contraction speed and high capacity for anaerobic ATP production on glycolysis; highly active in change-of-pace/stop-and-go activities

type IIa: high aerobic capacity
type IIx: lactate

49
Q

slow twitch (type 1)

A

generates energy through aerobic pathways

active in continuos activites

50
Q

exercise below lactate threshold

A

increased capillary density

increased mitochondrial density

ability to oxidize hydrogens more efficiently

delay in onset of lactic acid production

51
Q

training above lactate threshold

A

if production outweighs clearance, lactate is produced

52
Q

heat production

A

all of bodys metabolic processes result in heat production

calorie (kcal) is basic unit of heat measurement

heat production increases, oxygen production increases

53
Q

direct calorimetry

A

measures energy expenditure via heat production

54
Q

indirect calorimetry

A

all energy releasing reactions in humans depend on xygen use, so measuring oxygen consumption during physical activity provides an indirect yet accurate estimate of energy production

two types:
1. closed-circuit spirometry
2. open-circuit spirometry

55
Q

closed circuit

A

simple method that directly measures O2 uptake but has limited practical applications

subject breathes 100% O2 from spirometer, rebreathes only gas in spirometer
potassium hydroxide in circuit absorbs exhaled CO2
drum attached to spirometer revolves at known speed to record O2 uptake from changes in systems total volume

56
Q

open circuit

A

simple and practical way to measure O2 uptake and CO2 production to infer energy expenditure

inhales ambient air with constant composition
changes in %O2 and CO2 in expired air compared with % inspired ambient air indirectly reflect ongoing process of energy metabolism

bag technique, portable spirometry, computerized instrumentation

57
Q

FatMax

A

what % of VO2 max are we going to be burning fat

58
Q

TDEE

A

Total Daily Energy Expenditure

10% thermic effect of feeding (food intake, cold stress, thermogenic drugs)

15-30% thermic effect of physical activity (duration & intensity)

60-75% resting metabolic rate (fat-free body mass, gender, thyroid hormones)

59
Q

five factors that influence TDEE

A
  1. physical activity
  2. diet-induced thermogenesis
  3. calorigenic effect of food on exercise metabolism
  4. climate
  5. pregnancy
60
Q

energy required to utilize 100 kcals each (pure sugar, fat, starchy carbs, protein, fibrous carbs)

A

pure sugar: 2-3 kcals
fat: 5-7 kcals
starchy carbs: 10-12 kcals
protein: 25 kcals
fibrous carbs: 75 kcals

61
Q

training effect

A

increased O2 kinetic chain mechanics