Exam 1 Topical Antibiotics Flashcards
Topical Antibiotics are mostly used for _______.
mild skin infections
DDI and liver issues usually aren’t a problem with topical antibiotics because?
because topical antibiotics aren’t systemic.
Topical antibiotics- Common Agents:(5)
Bacitracin Mupirocin Neomycin Retapamulin Silver sulfadiazine Plus all the others we covered last semester (metro, gent, emycin, sulfa, etc.)
topical antibiotic with Mixture of polypeptides with broad G+ coverage- G+ coverage because most skin infections are caused by G+ (staph and strep)
Bacitracin
Bacitracin Use is limited to topical application due to ______.
severe nephrotoxicity with systemic use
Is Bacitracin available OTC?
yes
Does Bacitracin cover MRSA
NO
Mafenide (Sulfamylon) is used for treatments of _____.
burns
ADR for Mafenide (Sulfamylon)
ADR: Acid-base imbalance due to carbonic anhydrase inhibition, Sulfonamide allergy
Common, broad-spectrum topical abx used for minor skin infections
Neomycin
Neomycin is Available in combination with other abx like _____ for use OTC
polymixin
is neomycin for MRSA?
NO
with neomycin, there is an Increased risk for _______ with use
hypersensitivity reaction
Is Mupirocin (Bactroban) OTC?
no. Rx only
DOC for impetigo
Mupirocin (Bactroban)
this topical antibiotic is Also used for eradication of nasal MRSA colonization
Mupirocin (Bactroban)
Retapamulin (Altabax) is used to treat what?
impetigo
does Retapamulin (Altabax) treat MRSA?
NO
Is Retapamulin (Altabax) available OTC?
no, Rx only
two drugs that can treat impetigo
Mupirocin (Bactroban)
Retapamulin (Altabax)
Retapamulin May be used on resistant impetigo, however ____ is first choice for impetigo.
Mupirocin
Silver Sulfadiazine (Silvadene) is used for what treatment?
treatment and prevention of infection in burns
Some studies show ______ is just as effective as Silver Sulfadiazine
plain petrolatum
when prescribing Silver Sulfadiazine, should be Cautious prescribing to pts with ____ allergy
sulfa
topical antibiotic that Can discolor the skin
Silver Sulfadiazine
is Silver Sulfadiazine used on first degree burns?
no
