Exam 1 Topical Antibiotics

Question 1

Topical Antibiotics are mostly used for _______.

Answer 1

mild skin infections

Question 2

DDI and liver issues usually aren’t a problem with topical antibiotics because?

Answer 2

because topical antibiotics aren’t systemic.

Question 3

Topical antibiotics- Common Agents:(5)

Answer 3

Bacitracin
Mupirocin
Neomycin
Retapamulin
Silver sulfadiazine
Plus all the others we covered last semester (metro, gent, emycin, sulfa, etc.)

Question 4

topical antibiotic with Mixture of polypeptides with broad G+ coverage- G+ coverage because most skin infections are caused by G+ (staph and strep)

Answer 4

Bacitracin

Question 5

Bacitracin Use is limited to topical application due to ______.

Answer 5

severe nephrotoxicity with systemic use

Question 6

Is Bacitracin available OTC?

Answer 6

yes

Question 7

Does Bacitracin cover MRSA

Answer 7

NO

Question 8

Mafenide (Sulfamylon) is used for treatments of _____.

Answer 8

burns

Question 9

ADR for Mafenide (Sulfamylon)

Answer 9

ADR: Acid-base imbalance due to carbonic anhydrase inhibition, Sulfonamide allergy

Question 10

Common, broad-spectrum topical abx used for minor skin infections

Answer 10

Neomycin

Question 11

Neomycin is Available in combination with other abx like _____ for use OTC

Answer 11

polymixin

Question 12

is neomycin for MRSA?

Answer 12

NO

Question 13

with neomycin, there is an Increased risk for _______ with use

Answer 13

hypersensitivity reaction

Question 14

Is Mupirocin (Bactroban) OTC?

Answer 14

no. Rx only

Question 15

DOC for impetigo

Answer 15

Mupirocin (Bactroban)

Question 16

this topical antibiotic is Also used for eradication of nasal MRSA colonization

Answer 16

Mupirocin (Bactroban)

Question 17

Retapamulin (Altabax) is used to treat what?

Answer 17

impetigo

Question 18

does Retapamulin (Altabax) treat MRSA?

Answer 18

NO

Question 19

Is Retapamulin (Altabax) available OTC?

Answer 19

no, Rx only

Question 20

two drugs that can treat impetigo

Answer 20

Mupirocin (Bactroban)

Retapamulin (Altabax)

Question 21

Retapamulin May be used on resistant impetigo, however ____ is first choice for impetigo.

Answer 21

Mupirocin

Question 22

Silver Sulfadiazine (Silvadene) is used for what treatment?

Answer 22

treatment and prevention of infection in burns

Question 23

Some studies show ______ is just as effective as Silver Sulfadiazine

Answer 23

plain petrolatum

Question 24

when prescribing Silver Sulfadiazine, should be Cautious prescribing to pts with ____ allergy

Answer 24

sulfa

Question 25

topical antibiotic that Can discolor the skin

Answer 25

Silver Sulfadiazine

Question 26

is Silver Sulfadiazine used on first degree burns?

Answer 26

no