Exam 1 Questions Flashcards
Polychromasia on the peripheral smear represents an increase in what cell and is a measure of the bone marrow’s ability to replace red cells which have been destroyed?
Reticulocyte
A patient with microcytic anemia might have which of the following disease/s?
all of the above
Iron-deficiency anemia is characterized by
microcytic, hypo chromic
Autoimmune hemolytic anemia represents an abnormality in which:
self-recognition of an individual’s own red cell antigens is lost
Which of the following represents hereditary intracorpuscular defects?
Red blood cell (RBC) membrane defects
What membrane deficiency renders PNH erythrocytes more sensitive to lysis by complement?
GPI-anchor proteins
Refers to variations in red cell size:
anisocytosis
What is meant by medullary hematopoiesis?
hematopoiesis in the marrow
Chromic content of the red cell refers to:
hemoglobin
A general hematological test to determine a low red blood cell count would be:
hematocrit
Red cell shape that is due to excess membrane choloesterol and looks like a bulls eye
target cell
The mature erythrocyte, upon maturity, passes from a
nucleated to non-nucleated state
What is the primary function of hemoglobin
to carry oxygen
What is the normal lifespan of the RBC in circulation?
120 days
What is the mean corpuscular hemoglobin (MCH) used to measure?
hemoglobin content
A patient’s hemoglobin is 12 g/dL. What would you expect the hematocrit to be?
36%
Red cell inclusions include all except:
sickle cell
The government agency that develops technical standards and laboratory practice guidelines, including cytology guidelines is:
CDC
The five major departments found in a hospital clinical laboratory include all except:
cardiology
Which of the following agencies or organizations was created to make certain the quality of work done in the laboratory is reliable?
CLIA
One of the top five causes of pre-analytical errors is:
all of the above
The objective of CLIA’88 is to improve and ensure ______ of laboratory testing.
quality
Accuracy is defined as:
How close a test result is to the true value
The majority of clinical laboratory professionals are employed in:
Hospital laboratories
Why are laboratory data important for the diagnosis of disease?
all of the above
Which of the following is the basic difference(s) between a laboratory technician and a technologist/scientist?
all of the above
Blood specimens are unaccepetable for laboratory testing when?
all of the above
Laboratories performing which of the following types of test need to be enrolled in a CLIA approved proficiency testing program?
both B and C
leukemia of the myeloid lineage may include:
CML, polycythemia vera, essential thrombocytopenia, and chronic idiopathic myelofibrosis
(anything but lymphocytes)
what does a bone biopsy reveal in a patient with aplastic anemia
cell destruction and less new cells being made
fatty replacement
