Exam 1 Questions Flashcards

1
Q

Polychromasia on the peripheral smear represents an increase in what cell and is a measure of the bone marrow’s ability to replace red cells which have been destroyed?

A

Reticulocyte

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2
Q

A patient with microcytic anemia might have which of the following disease/s?

A

all of the above

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3
Q

Iron-deficiency anemia is characterized by

A

microcytic, hypo chromic

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4
Q

Autoimmune hemolytic anemia represents an abnormality in which:

A

self-recognition of an individual’s own red cell antigens is lost

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5
Q

Which of the following represents hereditary intracorpuscular defects?

A

Red blood cell (RBC) membrane defects

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6
Q

What membrane deficiency renders PNH erythrocytes more sensitive to lysis by complement?

A

GPI-anchor proteins

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7
Q

Refers to variations in red cell size:

A

anisocytosis

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8
Q

What is meant by medullary hematopoiesis?

A

hematopoiesis in the marrow

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9
Q

Chromic content of the red cell refers to:

A

hemoglobin

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10
Q

A general hematological test to determine a low red blood cell count would be:

A

hematocrit

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11
Q

Red cell shape that is due to excess membrane choloesterol and looks like a bulls eye

A

target cell

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12
Q

The mature erythrocyte, upon maturity, passes from a

A

nucleated to non-nucleated state

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13
Q

What is the primary function of hemoglobin

A

to carry oxygen

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14
Q

What is the normal lifespan of the RBC in circulation?

A

120 days

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15
Q

What is the mean corpuscular hemoglobin (MCH) used to measure?

A

hemoglobin content

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16
Q

A patient’s hemoglobin is 12 g/dL. What would you expect the hematocrit to be?

A

36%

17
Q

Red cell inclusions include all except:

A

sickle cell

18
Q

The government agency that develops technical standards and laboratory practice guidelines, including cytology guidelines is:

A

CDC

19
Q

The five major departments found in a hospital clinical laboratory include all except:

A

cardiology

20
Q

Which of the following agencies or organizations was created to make certain the quality of work done in the laboratory is reliable?

A

CLIA

21
Q

One of the top five causes of pre-analytical errors is:

A

all of the above

22
Q

The objective of CLIA’88 is to improve and ensure ______ of laboratory testing.

A

quality

23
Q

Accuracy is defined as:

A

How close a test result is to the true value

24
Q

The majority of clinical laboratory professionals are employed in:

A

Hospital laboratories

25
Q

Why are laboratory data important for the diagnosis of disease?

A

all of the above

26
Q

Which of the following is the basic difference(s) between a laboratory technician and a technologist/scientist?

A

all of the above

27
Q

Blood specimens are unaccepetable for laboratory testing when?

A

all of the above

28
Q

Laboratories performing which of the following types of test need to be enrolled in a CLIA approved proficiency testing program?

A

both B and C

29
Q

leukemia of the myeloid lineage may include:

A

CML, polycythemia vera, essential thrombocytopenia, and chronic idiopathic myelofibrosis
(anything but lymphocytes)

30
Q

what does a bone biopsy reveal in a patient with aplastic anemia

A

cell destruction and less new cells being made
fatty replacement