Exam 1 Pharm Maps Flashcards
What are some examples of opioid drugs (8)?
Morphine, Hydromorphone (Dilaudid), Fentanyl, Oxycodone (Oxycontin), Hydrocodone, Codeine, Hydrocodone/Acetaminophen (Vicodin), & Oxycodone/Acetaminophen (Percocet)
What are the reasons for taking opioids?
Moderate Pain
Severe Pain
Sedation
What is the action of opioids?
Binds to MU receptors in the central nervous system. Slows down CNS
What are the contraindications for opioids (3)?
- Decreased LOC, BP, or HR
- Severe Asthma
- Mixing with other opioids or CNS depressants
What are adverse reactions to Opioids (7)?
- Respiratory depressant
- Hypotension
- Bradycardia
- Purititis
- Sedation
- Addiction
- Chronic Constipation
When taking opioids, monitor what (3)?
RR, BP, & LOC
When taking opioids, assess pt.’s what?
Pain level
When taking opioids, check __ before administering.
Level of consciousness
When taking opioids, monitor for s/s of__.
Overdose
Opioid pt. education. May cause ___/___. Therefore pt. should do these 2 things.
May cause dizziness/lightheadedness
1. Stand or change positions slowly
2. Caution when driving or operating heavy machinery
Opioid pt. education. May cause ___. Recommend using a ___.
May cause constipation
Recommend using a stool softener daily
Avoid ___ or ___ when taking opioids.
Alcohol or other CNS depressants (benzo)
____ is often used in surgical procedures.
Fentanyl
Respiratory rate ___ hold and notify MD. (Opioid)
Less than 10
S/S of opioid overdose
Decrease LOC & decreased respirations
Antidote for opioid is ___.
naloxone (Narcan)
Naloxone (Narcan) has what kind of half-life?
Short half-life, and may need more than one dose
Monitor how much ___ with Percocet
Tylenol when Percocet is given with Tylenol
Non-opioid analgesics drug names (2)
Acetaminophen (Tylenol)
Tramadol (Ultram)
Reason for taking non-opioid analgesics
Mild to moderate pain
What non-opioid analgesics is given as a fever reducer?
Tylenol
What is the action of non-opioid analgesics?
Decreases prostaglandin synthesis = blocks pain impulses
Non-opioid analgesics contraindication
Liver disease
What should be avoided when taking tramadol?
SSRIs and MAOIs
Non-opioid analgesics adverse reactions (2)
- Hepatotoxicity
- GI upset
Assess ___ prior to administering non-opioid analgesics and ___ after
Pain level, 30 minutes after
How much Tylenol can be given in a 24 hour period?
3 grams
Non-opioid analgesics pt. education (4)
- Take as directed
- Caution if you have renal or liver problems
- Take with food
- Avoid alcohol
Antidote for acetaminophen is ___
Acetylcysteine
Tramadol is considered a ___ opioid
Weak opioid - inhibits the reuptake of serotonin
Tramadol can cause ___ if taken with an MAOI or SSRI’s
Serotonin toxicity (hyperreflexia, tremors, tachycardia)
NSAIDS drug names (4)
Salicylate Acid (Aspirin)
Ibuprofen (Motrin)
Ketorolac (Tordal)
Celecoxib (Celebrex)
Reasons for taking NSAIDS (4)
- Analgesic
- Anti-inflammatory
- Antipyretic
- Antiplatelet (aspirin)
NSAIDS action
Decreases production of prostaglandin release by blocking COX enzymes
NSAIDS contraindications (3)
- Peptic Ulcer Disease
- GI bleeding
- Vitamin K deficiency
NSAIDS adverse reactions (4)
- GI bleeding
- Stomach ulcers
- Nephrotoxicity with Tordal
- Hepatoxicity in some cases
Aspirin can cause __ in children.
Reye Syndrome
When taking NSAIDS monitor for ___
Unusual bleeding
Assess ___ before and ___ after administration of NSAIDS
Pain level, 30 minutes
Monitor ___ & ___ if taking Toradol
ALT/AST & BUN, Creat
Take NSAIDS with ___
Food or milk
Avoid ___ and ___ with NSAIDS
Alcohol and other hepatoxic drugs
Report any ____ or ___ to MD (NSAIDS)
Any black stools or noticeable bleeding
NSAIDS may cause ___
Kidney damage
Do not give ___ to children
Aspirin
Tordal should only be given for __
5 days
Do not ____ enteric coated aspirin
Crush
Aspirin is also used as an ___
Antiplatelet
S/S of Reye Syndrome (4)
Bleeding, tachycardia, seizures, & coma
What is another name for Feverfew?
Chrysanthemum parthenium
Reasons for taking Feverfew (2)
Arthritis & Migraines
Action of Feverfew
Reduces prostaglandin release = decrease inflammation (arthritis)
Inhibits vascular smooth muscle (reduce migraines)
Contraindications of Feverfew (2)
- Any blood thinner medications
- Pregnant or breastfeeding
Feverfew adverse reactions
An allergy to ragweed may be sensitive
Feverfew takes up to a ___ to work
Month
Why should pt.s NOT eat fresh feverfew leaves?
Causes mouth sores
The pt. is a young married female, what do you tell her about Feverfew?
Can bring on contractions if pregnant & can bring on menstrual cycle
What is another name for Gingko?
Gingko Biloba
Reason for taking gingko
Improves circulation
Action of gingko
Protect neurons from oxidation
Contraindications of gingko (2)
- Bleeding disorders
- Seizure disorders
Gingko adverse reactions (6)
- Headache
- Dizziness
- Heart palpitations
- Constipation
- Upset stomach
- Skin irritations
Do not eat ___ of gingko
Raw leaves
Monitor for ___ , __ & ___ when taking gingko
Bleeding
Sz activity
Skin irritations
What is another name for St. John’s Wort?
Hypericum perforatum
Reasons for taking St. John’s Wort (2)
Depression & Menopausal symptoms
Action of St. John’s Wort
Decreases serotonin receptors which affects the area of the brain associated with depression
St. John’s Wort contraindications
Warfarin (Coumadin)
- Reduces the effect
St. John’s Wort Adverse reactions (5)
- Anxiety & agitation
- Dizziness
- Dry mouth
- Photosensitivity
- Serotonin syndrome
When should pt.s taking St. John’s Wort notify their MD?
Chronic or sever GI symptoms
Reason for taking Echinacea
Common cold