Exam 1 Obj & SG (pt1) Flashcards
What are the building blocks of proteins?
AA’s
What determines the function of Amino Acids?
Side chain and chemical properties (R-group)
What are the 4 R-groups of Amino Acids?
Hydrophobic, hydrophilic, charged, and special
What is the basic structure of Amino Acids?
Amino group, Carboxylic acid group, hydrogen atom, and central carbon
At physiologic pH, the charged groups of amino acids are _____
Water soluble
These amino acids prefer to be inside a folded protein or covered by another part of a protein or a lipid membrane where they are hidden from the external water environment.
Hydrophobic (Water Hating) R-groups
These Amino Acids with partial charges from the hydroxyl (OH–) or amino (NH3+) parts of these R-groups, these amino acids prefer to be at or near the surface of a protein where they interact with surrounding water molecules and are often important at the active site of an enzyme.
Hydrophilic R-groups
These Amino Acids are either positively or negatively charged, and prefer to be at the surface of a folded protein or in contact with other charged atoms/molecules.
Charged R-groups
Which Amino Acids are often important at the active site of an enzyme?
Hyodrophilic R-groups
How are peptide bonds linked to each other?
By the carboxyl group of one amnio acid, to the amino group of another amino acid.
The precursors of the 20 amino acids found in humans are obtained from what?
carbohydrate metabolism
What predicts the folding patterns, binding sites, and other interactions of peptide bonds?
The R-groups
How is a primary peptide structure bonded?
Linked by peptide bond between amine and carboxylic acid
What is the backbone of a primary structure?
Amine—α carbon—carbonyl—Amine—α carbon—carbonyl
What forms a secondary structure?
Linear chain of amnio acids, in which the C-N and C-C bonds, rotate around the central carbon atom.