EXAM 1 FLASHCARDS

1
Q

how are natural selection and artificial selection the same?

A

both drive the evolution of species by selecting traits that are passed onto future generations

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2
Q

how are natural selection and artificial selection different

A

natural selection: driven by environmental pressures over long periods
- no specific goal

artificial selection: driven by human choices and can occur relatively quickly.
- goal-oriented, aiming to produce specific traits.

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3
Q

what is a common descent

A

all life can be traced back to a common ancestor

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4
Q

what is a paradigm shift?

A

fundamental change in the way we think about and study the origins of diversity of life and relationships between species (nature)

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5
Q

what three components must be present in a population in order for natural selection to occur?

A
  1. variation
  2. inheritance of variation
  3. differential reproductive success: more offspring are produced than can survive, those that are best adapted to their environment will produce more offspring and pass on more of their traits to the next generation.
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6
Q

what is uniformitarianism

A

the slow processes over long stretches of time can produce vast changes on Earth and the same geological process observable today have been acting throughout Earth’s history

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7
Q

what is the scientific method? what does it seek? and what is its order

A

Aims to explain the world based solely on natural phenomena (seeks explanation based on what is observed, tested, replicated, and verified)

  • Define question
  • Make observation
  • Form hypothesis
  • Make a prediction
  • Conduct experiment
  • Analyze results
  • conclusions
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8
Q

what is James Hutton known for

A

Father of modern geology who theorized that the Earth is much older than we thought and stated that the Earth is continuously being formed and reformed (rocks are eroded away

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9
Q

what is the inheritance of acquired characteristics

A

Jean-Baptiste Lamarck, hypothesis that traits acquired during the lifetime of an organism are passed onto its offspring

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10
Q

what is evolution

A

Change in allele frequencies in a population over time (process of descent with modification)

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11
Q

what is descent with modification

A

evolutionary process by which species change over time

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12
Q

what is Charles Lyell known for and what did he argue

A

Noticed that the pillars of pozzuoli had been pierced by a marine bivalve and concluded that the columns had once been underwater and raised back up by volcanic eruption

Argued that these same processes have operated over long periods of time in a slow, gradual manner (patterns we see today were probs seen in Earth’s history)

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13
Q

what did Charles Lyell theorize

A

Theorized that the earths crust formed via small change over a vast period of time

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14
Q

What were observations Darwin made on his trip on the HMS Beagle and how do they relate to natural selection?

A
  1. Fossil evidence of giant armadillos
  2. Finches with different beaks
  3. Tortoises with different necks and shells

How characteristics of organisms change over time
Come from common ancestors

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15
Q

what was Thomas Malthus known for

A

English economist who argued that the human population is growing faster than food production leading to the competition os resources

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16
Q

what was Jean-Baptists Lamarack known for (give an example)

A

he was the first to publicly suggest that species changed overtime and explained that the mechanism of change was the inheritance of acquired characteristics to offspring (Ex: giraffe neck)

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17
Q

what was Erasmus Darwin known for

A

Charles Darwin grandpa who classified facts about animals and argued that all life descended from a “single living filament”

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18
Q

what did Erasmus Darwin originally hypothesize

A

Initially hypothesized that humans initially walked on four limbs and that we descended from primate species (radical at the time)

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19
Q

what is Charles Darwin known for?

A

best known for his theory of evolution by natural selection (On the Origin of Species)

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20
Q

what was Alfred Russel Wallace known for?

A

English naturalist, surveyor, collector who noted differences between species in lands that were geographically separated in SA and SE Asia. 1858: He wrote his idea of natural selection on a malaria fever dream and sent his findings to Darwin. Published paper with Darwin about thoughts.

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21
Q

what were Charles Darwin’s two great insights

A
  1. Natural Selection: the environment selects on variation in the traits of individual organisms, because some variants are more successful than others at increasing the probability of survival and reproduction
  2. Common Ancestry: all species have descended from one or a few common ancestors. Species that share a recent common ancestor tend to resemble one another in many ways
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22
Q

what is natural selection

A

over time, beneficial traits become more common in a population due to increased survival and reproduction of individuals that have those traits

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23
Q

what is artificial selection and what are some examples

A

Process of human directed selective breeding aimed at producing a desired set of traits in the selected species (ex Darwin and strawberries and pigeons)

Human-driven analog to process of natural selection

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24
Q

what did humans rely on prior to the scientific method

A

mystical and spiritual explanations

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25
Q

what is the quote by Theodosius Dobzhansky

A

“Nothing in biology makes sense except in the light of evolution”

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26
Q

why was the voyage of the beagle so important and how long was the trip

A

1831-1836

the trip provided Darwin with the insight and observations that led him to write On the Origin of Species

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27
Q

which of the following question can be answered by the scientific method

A. is the starry night the most beautiful painting ever made

B. does drinking coffee on a daily basis result in a lower risk of heart disease

C. what is the song Stairway to Heaven

D. Is there life after death?

A

B. does drinking coffee on a daily basis result in a lower risk of heart disease

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28
Q

what did Jon Snow do during the cholera epidemic of 1854

A

he pinpointed the water pump he thought was the source of cholera and removed the Broad Street’s water pump handle

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29
Q

According to Lamarck’s theory of evolution, how did he propose that traits are passed on to offspring?

A

through passing along traits that were acquired during the lifetime of the organism

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30
Q

What observation led Charles Lyell to conclude that the columns of Pozzuoli had once been underwater?

A

the marble of pillars had been pierced by a marine bivalve

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31
Q

What was the central argument of Thomas Malthus in his ‘Essay on the Principle of Population’?

A

Human population growth will outpace food production and lead to limits on further population growth

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32
Q

what three observations helped support Darwin’s ideas on evolution

A
  1. Earthquake in conception- in the Valdivia region of Chile place of seafloor was lifted 9ft and exposed to air, which reminded Darwin of pillars and how they related to past times. Marine fossils were found in the Andes Mountains
  2. In South America fossils of extinct creatures such as the Glytodon were discovered and were giant relatives of armadillos. This helped Darwin develop this theory of evolution.
  3. Turtles, land/marine iguanas, and finches on the Galapagos island showed evolution and aided him in forming his ideas of natural selection.
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33
Q

What action did Alfred Russel Wallace take in 1858 that contributed to the theory of evolution by natural selection?

A

he wrote up his idea of natural selection during malarial fever dream

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34
Q

what was similar to living armadillos provided evidence for evolution.

A

glyptodont fossils

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35
Q

what related species were each very well-adapted to their specific niches, providing evidence for natural selection.

A

Galapagos finches

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36
Q

natural selection occurs when

A

beneficial traits become more common in a population because individuals who possess them survive and reproduce better than other individuals in the population

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37
Q

Artificial selection differs from natural selection because

A

in artificial selection, humans determine which traits are beneficial in a population and which are not

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38
Q

evolutionary thinking = ?

A

paradigm shift

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38
Q

what type of neck and shell did turtles who lived in humid areas with abundant vegetation have

A

short neck and dome shell

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39
Q

what type of neck and shell did turtles who live in a drier areas where vegetation was less abundant have

A

long neck and saddle shell

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40
Q

Darwin began introducing natural selection via what

A

artificial selection

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41
Q

what is LUCA

A

the last universal common ancestor

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42
Q

what is so important about the year 1859

A

Darwin’s book “On the Origin of Species” came out

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43
Q

the joint Darwin-Wallace paper came out in 1858 and comprised of four parts what were they?

A
  1. an introduction by Lyell and Hooker
  2. two articles by Darwin, each with a separate title
  3. one article by Wallace, also with a separate title
    (UNITED UNDER 1 PUBLICATION)
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44
Q

What years were Jean-Baptiste Lamarck active?

A

1744-1829

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45
Q

What years were James Hutton active?

A

1726-1797

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46
Q

What years were Charles Lyell active?

A

1797-1875

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47
Q

What year was the “Essay on the Principle of Population” published and who was the author

A

Thomas Malthus and 1798

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48
Q

What years were Erasmus Darwin active?

A

1731-1802

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49
Q

What years were Charles Darwin active?

A

1809-1882

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50
Q

What year was the “On the Origin of Species” published and who was the author

A

Charles Darwin and 1859-theory of natural selection

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51
Q

What years were Alfred Russel Wallace active?

A

1823-1913

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52
Q

What year did Alfred Russel Wallace write up his idea of natural selection?

A

1858

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53
Q

What is an example of variation?

A

different mice in a population having different coat colors: If all the mice had the same coat color natural selection could not occur; without variation, there is nothing for natural selection to select (needs to be a variation of traits among offspring)

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54
Q

How can variation in phenotypes arise?

A

through variation in genes alone, variation in environment alone, or through a combination of both.

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55
Q

What will occur if there is no genetic inheritance?

A

if traits were not passed down genetically, there would be no natural selection to ensure that beneficial traits increase in frequency or that less beneficial traits decrease. As a result, the distribution of trait varieties would remain largely unchanged from one generation to the next

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56
Q

What is an example of inheritance?

A

EX: offspring tend to resemble their parents so lady bugs that are red will tend to have red offspring and ladybugs that are yellow tend to have yellow offspring

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57
Q

What is an example for Differential Reproductive Success?

A

mice in sand: one with a cream coat one with a dark coat. Dark coat is eaten because more visible to predators compared to cream coat and only cream coat live and have babies….tons of babies that have cream coats in next gen (best fit trait)

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58
Q

What years were Thomas Malthus active?

A

1766-1834

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59
Q

How are adaptations and exaptations different?

A

Adaptations: an inherited trait that makes an organism more fit in its abiotic and biotic environments and that has arisen because of the direct action of natural selection for its primary contemporary function

Exaptations: trait that serves one purpose today but which evolved from a trait that served a different function in the past

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60
Q

What is the original source of variation in populations? what is an example? what do mutations do?

A

mutations (ex: antibiotic resistance)
mutations can change the phenotype an can be neutral or bad or good

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61
Q

Provide some examples of evolutionary trade-offs.

A

Peacock Feathers: those with larger, brighter feathers have more eye spots and are more attractive to females to reproduce BUT the larger these are the worse they fly and are more visible to predators

Ancient Arthropods
- Small clutches of large eggs: it takes a lot of energy to make these eggs that can better survive in the environment. Large eggs = fight off predators easily when fully grown 😁 but small clutches = only have few offspring to pass on their genes 🙁

  • Large clutches of small eggs: Small eggs = not able to fight off predators and win as much. Large clutches = there’s a greater chance that at least a couple will survive if predator attacks

Sickle Cell Anemia
- both hemoglobin = death by malaria
- heterozygous (one sickle cell and one hemoglobin mutated gene) = resistance against malaria (survival advantage)
- both sickle cell anemia = death by SCA

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62
Q

Natural selection does not result in a perfect organism. Why not? what are the constraints?

A

process of natural selection operates on physical structure in the material world, and as such is constrained by physical and mechanical laws. This process has no way of anticipating the future nor can it plan ahead. Selection favors changes that are immediately beneficial, not changes that may be useful sometime in the future.

  • Lack of genetic variation
  • Physical constrains
  • Developmental constraints
  • Natural selection lacks foresight and environment is always changing (cant keep up)
    - Ex: elephant cant get small legs
    - “Unintelligent design”
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63
Q

What characteristic was selected for in the fox farm experiments?

A

tameness: calmest, most pro-social-toward human animals

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64
Q

what is fitness and how is it measured

A

expected reproductive success of an individual who has trait/allele relative to other members of a population (measured by the number of offspring an individual has)

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65
Q

what is the norm of reaction

A

a curve representing phenotype for a particular genotype given a range of environmental conditions.
- a range of given phenotypes in a given environment (ex: height)

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66
Q

what is an adaptation

A

inherited trait that increases an individual’s fitness in its abiotic and biotic environment. Become more common in populations via natural selection for its current primary function (ex: cactus)

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67
Q

what is an exaptation

A

a trait that currently serves one function today, but which evolved from a trait that served a different function in the past

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68
Q

what is a genotype and what are 2 key pieces of information

A

Genotype: an organism’s genetic makeup (specific alleles or variants of a gene an organism has.

  • Interacts with environment to produce phenotype
  • Genotype doesn’t lead to just one phenotype, but instead multiple phenotypes that can be shown in a norm of reaction.
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69
Q

what is a phenotype and what can affect it

A

set of observable characteristics of an individual resulting from the interaction of its genotype with the environment

  • Both nature and nurture affect phenotype
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70
Q

what is domestication syndrome

A

suite of characteristics including floppy ears, short, curly tails, juvenilized facial and body features, reduced stress hormone levels, mottled fur, and relatively long reproductive seasons

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71
Q

what is the neural crest cell hypothesis

A

Proposes that selection for tame behavior results in a reduction of the number of neural crest cells migrating to diff parts of the body during embryonic development. which subsequently leads to changes in fur coloration, facial structure, the strength of cartilage (floppy ears, curly tails, etc.), hormone levels, length of the reproductive season, and more.

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72
Q

what is flight distance

A

measures how far an animal will flee from a threat before taking action (dogs with a shorter flight distance would get closer to humans for their food). an animal’s willingness to take risks when threatened

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73
Q

what is evolutionary trade-off

A

constraints may prevent simultaneous optimization of two traits, or different aspects of an individual trait. (There is a positive benefit to the trait, but also a negative at the same time)

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74
Q

What were Belyaev’s two hypotheses?

A
  1. The early stages of ALL animal domestication events involved human selection to choose the calmest, most prosocial-toward-human animals (tameness). IN OTHER WORDS: CHOOSE ANIMAL WHO IS THE MOST TAME WITH RESPECT TO HUMANS.
  2. All of the traits in the domestication syndrome were somehow or another, though he didn’t know how or why, genetically linked to genes associated with tameness.
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75
Q

Who was Lysenko? Include at least three major facts.

A

A pseudo-scientific charlatan who was a member of the Soviet Union’s Communist Party leadership (under Stalin) which attempted to glorify the avg. citizen.

  1. falsified experimental data in order to claim he had produced grain crops that produced high yields in the coldest years, and continued to do so for generations to come.
  2. began a crusade to discredit work in Mendelian genetics. He denounced geneticists, both overseas and the Soviet Union. He tried to shut down the Institute of Cytology and Genetics, which included Belyaev’s experiments.
  3. placed in charge of all policy regarding the biological sciences in July 1948. Gave a speech in 1948 which discredited Mendelian genetics, resulting in subsequent firing of thousands of Soviet geneticists (and likely the jailing and murdering of others).
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76
Q

Who made sure that Lysenko didn’t shut down the fox farm experiments

A

Khrushchev’s (supporter of Lysenko) daughter Rada had trained as a biologist and understood Lysenko was a fraud. She managed to convince her father to let the Institute of Cytology and Genetics remain open

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77
Q

The suite of traits seen in many domesticated animals that is collectively known as the “domestication syndrome” includes which of the following? (multiple answers)

A. floppy ears

B. short reproductive seasons as compared to wild counterparts

C. increased stress hormone levels

D. curly tails

E. juvenile facial features (large eyes, reduced teeth)

A

A. floppy ears
D. curly tails
E. juvenile facial features (large eyes, reduced teeth)

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78
Q

T/F: Trofim Lysenko, who became director of the Institute of Genetics of the Academy of Sciences of the U.S.S.R, was a trained scientist known for his replicable experiments on agricultural crops.

A

FALSE

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79
Q

The neural crest cell hypothesis suggests that the observed suite of characteristics that appear in animals that display the “domestication syndrome” are a result of

A

a reduced number of neural crest cells migrating to different parts of the body during embryonic development.

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80
Q

Belyaev hypothesized that which of the following about animal domestication events in human history?

a. Domestication events have involved human selection for the animals that are most aggressive toward other animals.

b. All traits in the domestication syndrome were genetically linked.

c. Domestication events have involved human selection for the animals that are most tame with respect to humans.

d. all of the above

e. B and C

A

e. B and C
- All traits in the domestication syndrome were genetically linked.
- Domestication events have involved human selection for the animals that are most tame with respect to humans.

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81
Q

T/F: Selection for tameness alone in foxes can lead to the traits associated with the domestication syndrome.

A

TRUE

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82
Q

T/F: The changes observed in the Belyaev fox populations are an example of evolution driven by artificial selection.

A

TRUE

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83
Q

How did Belyaev and his research team determine which foxes would be allowed to breed / parent the next generation of foxes?

A

they selected the foxes that were in the top 10% on a scale measuring tameness.

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84
Q

Which of the following can be concluded based on Belyaev’s experiments?

a. Domestication events require at least 1,000 generations.

b. Selection for tameness alone can lead to domestication syndrome in foxes.

c. The neural crest cell hypothesis can explain the phenomenon known as domestication syndrome.

d. all of the above

A

b. Selection for tameness alone can lead to domestication syndrome in foxes.

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85
Q

By generation 15, which of the following traits had emerged in the fox population? (Check all that apply.)

A. foxes wagged their tails when humans approached

B. floppy ears and curly tails

C. foxes licked the hand of experimenters

D. stress hormone levels increased

E. serotonin hormone levels decreased

A

A. foxes wagged their tails when humans approached

B. floppy ears and curly tails

C. foxes licked the hand of experimenters

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86
Q

Which key things did Lysenko do?

A
  1. He was a member of the Soviet Union’s Communist party under Stalin.
  2. He falsified experimental data in order to claim he had produced grain crops that produced high yields in the coldest years, and continued to do so for generations to come.
  3. He tried to shut down the Institute of Cytology and Genetics, which included Belyaev’s experiments.
  4. He gave a speech in 1948 which discredited Mendelian genetics, resulting in subsequent firing of thousands of Soviet geneticists (and likely the jailing and murdering of others).
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87
Q

Which features of a cactus is an adaptation to its environment favored by natural selection?

A
  1. sharp spines to deter herbivores
  2. flowers to attract pollinators
  3. waxy cuticle to prevent water loss
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88
Q

match this definitions with these terms: variance, inheritance, differential reproductive success

Some beetles were brightly colored, some were dull in coloration.

brightly-colored individuals are bitter and predators avoid them, resulting in better survival and passing along of more genes

beetles resemble their parents in coloration

A

Some beetles were brightly colored, some were dull in coloration. = VARIATION

brightly-colored individuals are bitter and predators avoid them, resulting in better survival and passing along of more genes = DIFFERENTIAL REPRODUCTIVE SUCCESS

beetles resemble their parents in coloration = INHERITANCE

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89
Q

For traits to evolve by natural selection, individuals must experience differential reproductive success. This means that

A

individuals with certain traits are more successful than others in the population at surviving and reproducing

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90
Q

Antibiotic resistance evolves quickly because

A

antibiotics impose strong selection for resistance

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91
Q

T/F? Individual organisms may evolve (in a biological sense) during the course of their lives.

A

FALSE (populations are the ones that evolve)

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92
Q

How did the study sites differ in the mountain streams for guppies?

A

the sites above the waterfalls had lower predation rates than the sites below the waterfalls

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93
Q

What was observed when guppies were moved from high to low-predation sites?

A

females produced fewer offspring that were larger

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94
Q

What statements correspond with the sickle cell anemia example within the slides?

A
  1. incidence of the sickle cell allele is correlated with the incidence of malaria in Africa
  2. Sickle cell allele has been selected for in malaria-prone regions because it carries a survival advantage against malaria
  3. individuals that are heterozygous at the Hemoglobin locus (one normal, one sickle cell allele) have resistance against malaria
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95
Q

Natural selection is a process that results in

A

evolution of populations

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96
Q

what are 4 key points to remember about mutations and how they generate variation

A
  1. they are random
  2. mutations can change phenotype
  3. many are neutral or deleterious (confer negative result = less fit)
  4. some are positive for fitness
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97
Q

what do we look at when studying natural selection

A

how a trait (allele) of interest changes (or doesn’t change) over time

98
Q

traits may be…

A
  1. morphological
  2. behavioral
  3. physiological
  4. genetic
99
Q

what is the smallest biological unit that evolves

A

Population (NOT individuals)

100
Q

____ are the object of explanation, while populations are the _____ of _____

A

traits = object of explanation
populations = level of analysis

101
Q

upstream sites typically have _____ predation levels on adult guppies while downstream sites have _____ predation levels on adults

A

upstream = lower predation
downstream = higher predation

102
Q

what was the hypothesis of the guppies experiment?

A

at high predation sites, selection favors guppies that produce many small young, but at low predation sites selection is reversed, favoring larger but fewer offspring

103
Q

guppies transplanted from high to low predation site evolved what type of trait over time

A

brighter coloration (less predation = brighter guppies)

104
Q

what are the limitations to natural selection what was an example given in the lecture

A
  1. lack of genetic variation (selection can’t generate a new trait that just appears)
  2. physical constraints
  3. developmental constraints (organism develops in certain order during embryonic development)
  4. evolutionary arms race
  5. natural selection lacks foresight and environment is always changing

(ex: elephants are never going to develop thin legs because they require thick legs to hold themselves up so selection can’t create elephants with thin legs)

105
Q

How did Dmitri Belyaev use the scientific method observation step in his fox farm experiment?

A

Belyaev knew many domesticated species share a suite of characteristics and noticed over time, that species display traits in the domestication syndrome. He wanted to see if tameness was correlated to this.

106
Q

How did Dmitri Belyaev use the scientific method hypothesis step in his fox farm experiment?

A

early stages of all animal domestication events involved choosing the calmest, most prosocial-toward-human animals (tameness). 2) all of the traits in domestication syndrome were genetically linked with genes associated with tameness

107
Q

How did Dmitri Belyaev use the scientific method experiment step in his fox farm experiment?

A

took sample size of hundreds of silver foxes. Top 10% of tamest = parent to next gen. Fox score on tameness scale was SOLE criteria for selecting the parent foxes to next gen.

108
Q

How did Dmitri Belyaev use the scientific method results step in his fox farm experiment?

A

floppy ears
curly tail
DECREASE of stress hormone levels
adrenal gland gets smaller
serotonin levels INCREASED
“mutt-like” fur patterns
juvenilized facial features and body shapes.

109
Q

How did Dmitri Belyaev use the scientific method conclusion step in his fox farm experiment?

A

Belyaev was correct that selection on tameness alone leads to the emergence of traits in the domestication syndrome.

110
Q

How were the results and methods of the Fox experiments related to the concept of evolution?

A

It demonstrated an example of artificial selection in which humans choose which animals are the tamest to parent the next generation so that their offspring can display domestication syndrome characteristics.

  • Variation: tame or untamed
  • Heritability: symptoms of domestication syndrome due to neural crest cell movement
  • Reproductive success: artificial selection of tame foxes
111
Q

What are the features of domesticated syndrome?

A

floppy ears
short curly tails
juvenilized facial and body features
reduced stress hormone levels
mottled fur
relatively long reproductive seasons

112
Q

What explanations/hypothesis have been proposed to explain how this occurs in domesticated animals?

A

Hypothesis to explain the link to domestication syndrome and tameness:
- Balyaev’s 2 hypothesis

The hypothesis of how tameness caused the traits:
- hypothesized that the process of domestication was in part the result of changes in gene expression patterns—when genes “turn on” and “turn of” and how much protein product they produce

113
Q

How did the fox farm experiment help to illuminate our understanding of how dogs might have been domesticated?

A

It demonstrated that the trait for tameness can be selected for, and early humans developed relationships with dogs for protection, and as they continued to “select” tameness as a trait it caused traits to go through evolution and change

114
Q

How did Lysenko almost shut down the farm fox experiments?

A
  1. Geneticists present during speech were forced to stand up and refute their scientific knowledge and practices. If they refused, they were thrown out of the Communist Party. Dozens (perhaps hundreds) were jailed and few murdered.
  2. Lysenko-created committee from Moscow was sent to Akademgorodok, and said the direction of the Institute of Cytology and Genetics was methodologically wrong, thus Nikita Khrushchev came to investigate and almost shut down
115
Q

What was the hypothesis pertaining to how wolves were domesticated into dogs that was presented in the clip of “dogs that changed the world”?

A

Raymond Carpenter hypothesized that the creation of the 1st Stone Age village created a brand new ecological niche. “once an animal moves into a place like this then all of a sudden there is going to be competition between them. those who win the fights will occupy in the dump”. Dogs with short flight distance = feed around humans = that’s the animal that will survive in dump.

116
Q

what are some examples of unintelligent design

A
  1. left recurrent laryngeal nerve of land vertebrates
  2. Human eye’s blind spot
  3. Spotted hyena birth canals
  4. Adult Saturniidae have no feeding mouthparts or digestive tract
117
Q

What are the taxonomic ranks, in order from most general to most specific, of our modern classification system

A

Domain (most general)
Kingdom
Phylum
Class
Order
Family
Genus
Species (most specific)

Dear King Philip Come Over For Good Soup

118
Q

What is meant when we say that “phylogenies are hypotheses”?

A

Visual representation of hypothesized evolutionary relationships between species. They are continuously updated as new evidence is unveiled

119
Q

what is a node

A

where branches split; indicate common ancestors of taxa that come after split point

120
Q

what are branches on phylogenetic tree

A

represent different evolutionary lineages

121
Q

what are branch tips on phylogenetic tree

A

taxa of interest

122
Q

what is sister taxa

A

taxa derived from same node

123
Q

what is the root of a phylogenetic tree

A

base of tree; represents the common ancestor to all taxa on tree
LUCA (last universal common ancestor) would be root of the tree of life of organisms living today

124
Q

how are monophyly, polyphyly, and paraphyly different from each other

A

mono = includes common ancestor + all its descendants

poly = multiple ancestral lineages but NOT include common ancestor

para = includes the common ancestor but not all descendants included (some left out)

125
Q

what are examples of paraphyletic groups

A
  1. fish
  2. “raptors”: falcons, owls, eagles, and ospreys
126
Q

What kinds of information / data can be used to build phylogenetic trees?

A

Character: any observable characteristic of organism (physical, genetic, biochemical, etc.) that has different traits
- Trait: character state

Descent with Modification: organize species into nested groups based on shared derived characteristics
- Ancestral character: the character state (trait) present in the common ancestor
- Derived character: all other variant forms of the character that arose later within the groups

127
Q

How are analogous traits and convergent evolution related to each other?

A

They both are superficial similarities that arise via different evolutionary lineages and misrepresent common decent.

128
Q

what is Linnaean hierarchy

A

the hierarchical system for classifying organisms (each organism is given a unique name)

129
Q

what is taxonomy

A

the science of naming organisms

130
Q

what is taxon/taxa

A

major group of organisms at each level in the hierarchy (a group of related organisms)

131
Q

what is taxonomic rank and examples that were present in the lecture

A

indicate the general degree of inclusiveness per group

EX: Class: Aves; Class = rank and Aves = taxa

EX: Phylum: Chordata; Phylum = rank and Chordata = taxa

132
Q

what is scientific name

A

formal name of a species that consists of two words (genus + specific epithet)

133
Q

what is phylogeny (phylogenetic tree)

A

visualization of branching relationships of populations as they give rise to descendant population over time

134
Q

what is monophyletic group and clade

A

includes common ancestor and all its descendants (and no others); representative of descent with modification

   - Clade: representation of a monophyletic group on a tree
135
Q

what is a polyphyletic group

A

“poly” = many and “phyla” = tribe/race which includes organisms from multiple ancestral lineages but DOES NOT include the common ancestor

136
Q

what is a paraphyletic group

A

“para” = beside and “phyla” = tribe/race where groups of organisms are left out from all other descendants of common ancestor. Contains the group’s common ancestor but NOT ALL its descendants.

137
Q

what is polytomy

A

node with more than two branches arising from it that indicates uncertainty/unresolved lineages

138
Q

what is a homologous trait

A

character similarity results from common ancestry

139
Q

what is an analogous trait

A

superficial similarities that arise via different evolutionary lineages (often convergent evolution); misrepresents common descent (homoplasy is the related term)

140
Q

what is convergent evolution

A

two or more populations or species evolve similar traits due to similar selective pressures

141
Q

Which of the following statements best describes a monophyletic group?

a. it contains multiple lineages of taxa that have different common ancestors

b. it includes random groupings of species without evolutionary relationship

c. it consists solely of one common ancestor and all of its descendants

d. it is a representation of all known species in a taxonomic classification

A

c. it consists solely of one common ancestor and all of its descendants

142
Q

How are polyphyletic groups different from monophyletic groups?

a. the grouping does not include a common ancestor to all taxa within the group

b. polyphyletic groups contain multiple phyla, while monophyletic groups include just one

c. the grouping does not include all descendants of the common ancestor of the taxa within the group

d. the only known polyphyletic grouping is the marine mammals

A

a. the grouping does not include a common ancestor to all taxa within the group

143
Q

What is the main difference between a homologous trait and an analogous trait?

a. analogous trait describes similarities inherited from a common ancestor, while a homologous trait involves physical resemblance only

b. analogous traits describe a common genetic origin, while homologous traits refer to traits acquired in the course of an individual’s life span

c. a homologous trait is based on common ancestry, while an analogous trait is based on superficial similarities from different evolutionary lineages

d. homologous traits reflect genetic similarities whereas analogous traits reflect cultural inheritance

A

C. a homologous trait is based on common ancestry, while an analogous trait is based on superficial similarities from different evolutionary lineages

144
Q

What can be said about the similar flight patterns observed in hummingbirds and hummingbird moths?

a. the wings of hummingbirds and hummingbird moths are analogous traits

b. hummingbirds and hummingbird moths should be in a separate clade based on this characteristic

c. it is likely the result of shared evolutionary lineage including a common ancestor that had wings

d. it is likely the result of convergent evolution as they experienced similar environmental pressures

A

d. it is likely the result of convergent evolution as they experienced similar environmental pressures

145
Q

Carolus Linnaeus devised what…

A

our modern biological system

146
Q

System Naturae was first published by who? in what year? what did it include?

A

Linnaeus in 1735 and included ~10,000 species

147
Q

scientific names allow what?

A

precise communication about species, as opposed to “common names” that may vary both culturally and geographically

148
Q

if you are the first to describe a taxon in a publication you get to?

A

name that taxon and some creative liberties may be taken

149
Q

what is phylogenetic systematics

A

the modern science of classifying organisms based on evolutionary relationships

150
Q

what are the types of data used to test/build phylogenetic trees

A
  1. fossil record
  2. phenotypes (morphological, physiological)
  3. behavioral
  4. embryological
  5. genetic
151
Q

what is the goal of phylogenetic systematics

A

to construct monophyletic groups in trees

152
Q

what animal is an example of polyphyletic group

A

marine mammals

153
Q

when constructing phylogenies it is important to use…

A

homologous traits NOT analogous traits

154
Q

what is a common ancestor

A

Darwin hypothesized all species have descended from one or a few common ancestors, species that share a recent common ancestor tend to resemble one another in many respects.

155
Q

what are common ancestors represented by in a phylogenetic tree

A

nodes

156
Q

what is the common ancestor of various clades called on a phylogenetic tree

A

root

157
Q

what does a clade represent

A

represents a monophyletic group on a tree

158
Q

what were the findings of Mendel’s monohybrid cross what was it the basis of?

A
  1. F2 generation = 3:1 phenotypic ratio
  2. Ratios of F2 generation from monohybrid cross became basis for the law of segregation
159
Q

what is the law of segregation

A

each cell contains two copies of a gene (alleles on the homologous chromosome). These two alleles are segregated from each other in gamete formation so that each gamete receives only one member of the pair (no blended inheritance)

160
Q

what were the hypotheses of the dihybrid cross and the findings

A

hypothesizes that F1 generation would be 100% displaying 2 dominant characteristics. For F2 hypothesized a 3:1 ratio but instead got 9:3:3:1. Basis for law of independent assortment

315 round and yellow (9/16)
101 wrinkled and yellow (3/16)
108 round and green (3/16)
32 wrinkled and green (1/16)

161
Q

what is the law of independent assortment

A

alleles for different genes are inherited independently of each other. TRUE for unlinked loci on different chromosomes; NOT true for linked loci that are close together on same chromosome

162
Q

what is meiosis in regards to the law of independent assortment

A

every chromosome pair orients independently of all others at metaphase I; orientation of lineup is by chance

163
Q

what were Darwin’s contributions to our understanding of genetics/inheritance/molecular biology?

A
  1. 1859: On the Origin of Species = inheritance as key “ingredient” for natural selection to occur
  2. 1868: The Variation of Animals and Plants Under Domestication = Pangenesis: described units of inheritance between parents and offspring as gemmules
164
Q

what were Mendel’s contributions to our understanding of genetics/inheritance/molecular biology?

A
  1. 1866: experiments on plant hybridization (pea plants)
  2. Developed monohybrid cross where F2 generation produced 3:1 ratio and led to the basis for law of segregation
  3. Developed dihybrid cross where the F2 generation displayed 9:3:3:1 ration instead of 3:1 and was the basis of the law of independent assortment
165
Q

what were Thomas Hunt Morgan’s contributions to our understanding of genetics/inheritance/molecular biology?

A
  1. In 1910 analyzed white-eyed mutant fly and recognized that eye color and sex were both tied to chromosomes.
    • Genes located on chromosomes, and some genes are linked
  2. Confirmed chromosomal theory of inheritance: chromosomes carried the factors associated with Mendelian inheritance
166
Q

what were Hershey and Chase’s contributions to our understanding of genetics/inheritance/molecular biology

A

1952 they definitely show that DNA is the molecule of heredity by labeling protein or DNA of bacteriophage with radioactive elements and saw that what had entered into bacterial cells was DNA NOT proteins

167
Q

what were Franklin, Watson, Crick, and Wiklin’s contributions to our understanding of genetics/inheritance/molecular biology

A

1953 published DNA structure where they found that DNA is double stranded and the strands are complementary, anti-parallel, and a double helix.

168
Q

how does the genotype becomes phenotype through the process of protein synthesis.

A

the central dogma
DNA —- transcription —> mRNA —- translation —> protein

169
Q

what is transcription

A

DNA -> mRNA (occurs inside nucleus): Complementary RNA strand is built from a DNA template (U instead of T in RNA)

  • carried out by enzymes called RNA polymerases.
170
Q

what is translation

A

mRNA -> protein (outside of nucleus in ribosome): string of amino acids built from mRNA code. It involves mRNA, tRNA and rRNA

171
Q

what is epigenetics what are 3 examples

A

Epigenetics: heritable mechanisms that alter gene expression without altering underlying DNA sequence

  1. DNA methylation
  2. Histone modification
  3. Small RNA molecules
172
Q

what are the major sources of genetic variation in populations

A
  1. Mutation*
  2. Recombination
  3. Migration
  4. Lateral gene transfer (especially in bacterial populations)
173
Q

what is a point mutation and what types of mutations are associated with it

A

single base change

  1. Synonymous = mutation is the same as original DNA sequence
  2. Non-synonymous = protein sequence that differs from original sequence
  3. Nonsense = code for stop codon
174
Q

what are insertions and deletions what can it cause?

A

Insertion (adding 1 or more base pairs) and Deletions (eliminating 1 or more base pairs.

  • Leads to frameshift = reading frame for ribosome is shifted
175
Q

what are the types of mutations that occur at the chromosome or whole-gene level

A
  1. Chromosomal duplication = chromosome is copied and inserted
  2. Chromosomal deletion = piece of chromosome is lose
  3. Inversion and Translocation = chromosomes are rearranged
176
Q

what are examples of diseases caused by deleterious mutations

A
  1. Cystic fibrosis: most commonly due to deletion of three nucleotides, resulting in one missing amino acid from CFTR protein (regulates salt and water flow)
  2. Sickle cell anemia: results from a single point mutation in gene for Hemoglobin
177
Q

what is a gene

A

sequence of DNA that codes for protein (“trait”)

178
Q

what is an allele

A

alternative form of a gene

179
Q

what is a genotype

A

alleles for a gene an individual possesses (in diploid organisms, homozygous or heterozygous)

180
Q

what is a phenotype

A

physical expression of genotype (observable traits)

181
Q

what is a homozygous genotype

A

genotype in which alleles are the same

182
Q

what is a heterozygous genotype

A

genotype in which alleles are different

183
Q

what is a dominant allele

A

allele that when inherited is expressed

184
Q

what is a recessive allele

A

allele that will ONLY be expressed if individual is homozygous for this allele

185
Q

what are homologous chromosomes

A

a pair of chromosomes in diploid cells; they are the same length, carry the same genes, but are NOT identical as one came from maternal parent and paternal parent.

186
Q

what is the thrifty phenotype hypothesis

A

fetuses that experience poor nutrition develop “thrifty” metabolisms that are much more efficient at hoarding energy. (link between poor fetal nutrition = obesity later

187
Q

what was the epigenetic effects observed in agouti mice

A

Pregnant mice got better prenatal care (normal diet + vitamin supplements (B12, folic acid, and choline) so when fat yellow female mice mated with fat yellow male mice = thin brown babies

188
Q

what was the epigenetic effects observed in voles

A

Baby voles are born with either a thick or thin coat. Gene for a thick coat is always there it’s just turned on or off depending on the level of light the mother senses in her environment around the time of conception (gets a weather forecast before it’s born to know which coat it should grow)

189
Q

what was the epigenetic effects observed in Daphnia

A

Produces offspring with a larger helmet and spines if it’s going to give birth in an environment crowded with predators

190
Q

what was the epigenetic effects observed in desert locust

A

Lives in two different styles depending on the availability of food sources and the density of the local locust population. When food is scarce (usually in their native desert habitat = locusts are born with coloring designed for camouflage and lead solitary lives. When significant rain produces major vegetation growth everything changes. As extra vegetation starts to die off, the locusts are crowded together and are born with bright colors and want company

191
Q

what was the epigenetic effects observed in lizards

A

Lizards are born with a long tail and large body or a small tail and small body depending on one thing only - whether their mother smelled a lizard-eating snake while pregnant. When babies are entering a snake-filled world, they are born with long tail and big body making them less likely to be snake food

192
Q

How has poor nutrition in pregnant sheep shown to affect offspring

A

Pregnant sheep that were underfed during the early days of pregnancy - before embryo was implanted in the uterus - gave birth to offspring that rapidly developed thickened arteries because their slower metabolisms stored more food as fat.

193
Q

How has poor nutrition in pregnant rats shown to affect offspring

A

When pregnant rats fed low-protein diet for just first four days of pregnancy - before embryo was implanted in uterus - their babies were prone to high blood pressure

194
Q

how did maternal behavior towards pups affect epigenome and phenotype

A
  1. Pups that were gently licked by mothers = confident rat babies that were relatively relaxed and could handle stressful situations
  2. Rats ignored by mothers = nervous wrecks
  3. Pups that were fawned over over = calm regardless of their natural mother’s behavior
  4. Rat pups that were attentively groomed by their mothers (biological or adopted) showed a decrease in methyl markers around the genes involved with the brain development
195
Q

Which of the following maternal effects have been observed by researchers? Check all that apply.

a. Sheep whose mothers were undernourished when pregnant showed signs of thickened arteries and increased weight when fed a normal diet (but not when also undernourished).

b. Human mothers who eat high-calorie/low nutrient diets will have offspring that are more likely to have high metabolic rates.

c. Rats whose mothers were fed a low-protein diet for the first four days of pregnancy were more likely to have high blood pressure.

d. Daphnia (water fleas) whose mothers are in environments with high levels of predators will have large spines.

e. Mice whose mothers received a diet with choline supplements have increased memory capacity.

A

a. Sheep whose mothers were undernourished when pregnant showed signs of thickened arteries and increased weight when fed a normal diet (but not when also undernourished).

c. Rats whose mothers were fed a low-protein diet for the first four days of pregnancy were more likely to have high blood pressure.

d. Daphnia (water fleas) whose mothers are in environments with high levels of predators will have large spines.

e. Mice whose mothers received a diet with choline supplements have increased memory capacity.

196
Q

T/F: Evidence shows that Epigenetic effects can only be passed on from mother to offspring (not from fathers).

A

FALSE

197
Q

Research has shown that men who smoke before puberty (OMG!) will have sons who

A. Are overweight more often than normal by age 9

B. Have more thickened arteries than normal by age 9

C. Have higher incidence of asthma than normal by age 9

D. Are smaller than normal by age 9

E. Are at higher risk of lung cancer

A

A. Are overweight more often than normal by age 9

198
Q

T/F: Identical twins have identical methylation patterns throughout their lives, even when they live in different environments.

A

FALSE

199
Q

T/F: Evidence shows that acquired changes to the epigenome within a person’s life may be passed on to their offspring.

A

TRUE

200
Q

The Punnett square for your F2 generation (monohybrid) should predict which of the following phenotypic ratios? (Y = yellow Dom and y = green recess)

A. 3 green : 1 yellow
B. 2 yellow : 2 green
C. 100% yellow
D. 3 yellow : 1 green

A

D. 3 yellow : 1 green

200
Q

Methylation of a gene results in

A. Mutation in the gene

B. Reduced expression of the gene

C. Greater expression of the gene

D. All of the above are possible results of methylation

A

B. Reduced expression of the gene

200
Q

Early in human evolution, individuals with a thrifty phenotype (ability to store more calories as fat) were at an advantage over those who did not have thrifty phenotype in times of famine; natural selection favored these individuals and the thrifty phenotype became common in humans. This is known as the

A

thrifty phenotype hypothesis

200
Q

If “Y” is the allele for yellow, and “y” is the allele for green, what are the genotypes of the true-breeding yellow and green plants in the “P” generation?

A. PP and PP
B. Pp and Pp
C. PP and pp
D. pp and it is unclear what the dominant yellow plant would be

A

C. PP and pp

200
Q

Which of the following statements is TRUE?

A. Epigenetic changes occur only in noncoding regions and thus have no effect on gene expression.

B. Epigenetic changes alter DNA sequences, but not the way that genes are expressed.

C. Epigenetic changes to gene expression can be heritable even though the DNA sequence is not altered.

D. Epigenetic changes change allele frequencies in populations.

E. Epigenetic changes occur due to mutation.

A

C. Epigenetic changes to gene expression can be heritable even though the DNA sequence is not altered.

200
Q

Michael Meaney’s studies on rat behavior showed that (check all that apply)

a. interactions between rat mothers and their offspring affected the mother’s ability to handle stress.

b. rat pups whose mothers were attentive (licked them/interacted positively with them) grew into calm adult rats who were able to handle stress well.

c. rat pups whose mothers ignored them grew into adult rats who handled stress poorly.

d. when rat pups whose biological mother was negligent were given a surrogate mother who was attentive, they still grew into adult rats who handled stress poorly.

e. personality (anxious or calm) in rats is determined solely by genetics.

f. rat pups whose mothers were attentive had reduced methylation of genes involved in brain development.

A

b. rat pups whose mothers were attentive (licked them/interacted positively with them) grew into calm adult rats who were able to handle stress well.

c. rat pups whose mothers ignored them grew into adult rats who handled stress poorly.

f. rat pups whose mothers were attentive had reduced methylation of genes involved in brain development.

200
Q

All of the following events were correlated with a similar phenomenon. What was it?

  1. September 11, 2001 terrorist attacks in the U.S.
  2. the tumultuous reunification of Germany in 1990
  3. the 10-day war in Slovenia (1991)
  4. the Hanshin earthquake in Kobe, Japan (1995)

A. female offspring of pregnant women affected by the event showed increased rates of breast cancer in adulthood

B. pregnant women affected by the event miscarried at increased rates, regardless of sex of baby

C. babies who were born to mothers affected by the event were more likely to be diagnosed with ADHD

D. male birth rates increased among women affected by the event

E. male birth rates decreased among women affected by the event

A

E. male birth rates decreased among women affected by the event

200
Q

Female mice who express the agouti phenotype (fat, yellow mice) give birth to mice who do not express the agouti gene (brown, skinny mice) when

A. they are fed a diet that is supplemented with extra calories.

B. they are fed a diet that is supplemented with prenatal vitamins while pregnant.

C. they increase their exercise levels by 50%.

D. all of the above.

A

B. they are fed a diet that is supplemented with prenatal vitamins while pregnant.

201
Q

How many squares should your Punnett square have for a dihybrid cross?

A. 4
B. 8
C. 16

A

C. 16

202
Q

DIHYBRID: Assuming R is the allele for round and r is the allele for wrinkled, and Y is the allele for yellow and y is the allele for green, what are the genotypes of the F1 generation that parent the F2 generation in this cross? (Hint: you might need to perform a cross of the P generation to produce the F1 if you are not sure.)

A. RRYY and rryy
B. RRyy and rrYY
C. RrYy and RrYy

A

C. RrYy and RrYy

203
Q

T/F: A 16-square Punnett square (a two-trait cross) will always predict a 9:3:3:1 phenotypic ratio.

A

FALSE

204
Q

Gregor Mendel’s law of segregation states that

A. the allele passed down to the next generation at one locus is independent of the allele that is passed down at another locus

B. two copies of each gene are found in a gamete

C. traits from each permanently blended in their offspring

D. each diploid individual has two copies of every gene and that the two gene copies separate with equal probability into the individual’s gametes

A

D. each diploid individual has two copies of every gene and that the two gene copies separate with equal probability into the individual’s gametes

205
Q

What is NOT true regarding the Law of Independent Assortment as it pertains to genetic inheritance?

A. it applies to loci that are close together on the same chromosome

B. it explains why many traits are inherited independently of each other

C. it states that alleles for different genes are inherited independently of each other

D. it is related to the random orientation of chromosome pairs during metaphase I of meiosis

A

A. it applies to loci that are close together on the same chromosome

206
Q

T/F: Mendel knew that DNA was the hereditary material.

A

FALSE

207
Q

Which of the following came first?

A. Darwin’s publications on On the Origin of Species

B. the use of the term “gene” to describe hereditary units

C. the discovery of DNA as the hereditary material

D. Mendel’s publication of his laws of inheritance

E. discovery of DNA structure

A

A. Darwin’s publications on On the Origin of Species

208
Q

If a DNA template strand reads “TAGCCGATA” , what would the complementary mRNA strand be? Transcribe from left to right.

A

AUCGGCUAU

209
Q

what is the ribosome

A

cellular structure responsible for coordinating the translation process

210
Q

what is RNA polymerase

A

primary enzyme class responsible for building mRNA

211
Q

what is a codon

A

set of three RNA nucleotides which code for a single amino acid

212
Q

Which of the following is true about the brown and yellow agouti mice in the study? Check all that apply.

A. their epigenetic methylation patterns are different
B. their genotypes are different from each other
C. their mothers were fed different diets

A

A. their epigenetic methylation patterns are different
C. their mothers were fed different diets

213
Q

T/F: Most mutations are beneficial to fitness in the individual.

A

FALSE

214
Q

who and what year coined the term “gene”

A

Wilhelm Johannsen (Danish botanist in 1909) who coined the term gene to name hereditary factors described by Mendel

215
Q

what is the modern definition of gene

A

nucleic acid sequence that encodes for a protein

216
Q

what were Darwin’s pangenes

A

proposed units of inheritance passed from parents to offspring

217
Q

what are the subunits of DNA

A

nucleotides

218
Q

what does a single DNA nucleotide consist of

A

Deoxyribose sugar
Phosphate group
Nitrogenous base (A, T, C, or G)

219
Q

who and what year was the first to publish the central dogma

A

Francis Crick in 1958

220
Q

what is the mRNA in translation

A

the code

221
Q

what is transfer RNA (tRNA)

A

carries amino acids and matches them with codons in mRNA using anticodons

222
Q

what do ribosomes (rRNA) do in translation

A

coordinate the functions of mRNA and tRNA

223
Q

what do mRNA letters code for

A

amino acids

224
Q

what is the universal code

A

all living things use same “code” (piece of evidence for common ancestry)

225
Q

what is the redundant code

A

more than one codon for most amino acids

226
Q

what is meant when someone refers to the “modern synthesis”?

A

” The difference between the Mendelians and the biometricians began to dissolve with experimental work in the 1930s and the 1940s.

  • the early 20th century integration of Charles Darwin’s theory of evolution by natural selection with Gregor Mendel’s ideas on genetics, creating a comprehensive understanding of how evolution occurs at the population level, incorporating concepts like mutation, gene flow, and genetic drift
227
Q

How did Darwin think that traits were inherited? How was his idea incorrect?

A

Darwin’s book “The variation of animals and plants under domestication” Darwin believed that traits were inherited via pangenesis. Pangenesis: (thought parents broke off parts of body, gemmules, and passed to egg then embryo.)

Darwin was incorrect because traits are passed on through the inheritance of genes through chromosomes (genetic inheritance), not blending or gemmules through pangenesis. We now know gametes are formed through meiosis

228
Q

Who was Wilhelm and what did he do?

A

1909: coined the term “gene” to name hereditary factors described by Mendel
- Got the name “gene” from Darwin’s Pangenes
- Modern definition of gene= nucleic acid sequence that encodes for a protein

229
Q

What is the definition of a mutation?

A

A change to the DNA sequence of the organism, the primary source of genetic variation.

230
Q

what is aneuploidy

A

presence of an abnormal number of chromosomes (45 or 47 in humans) instead of the usual 46. can lead to genetic disorders and developmental issues

231
Q

what is recombination

A

remixes existing variation, present in parents, into new genetic combinations that appear in their offspring. Occurs through crossing-over which is the physical exchange of segments of DNA during meiosis

232
Q

what is methylation

A

the addition of a methyl group (CH3) to DNA, typically at cytosine bases which can regulate gene expression and play a significant role in phenotype plasticity, adaptation, and evolution

233
Q

what is epigenetic effects

A

refers to heritable changes in gene expression that do not involve alteration to DNA sequence, often influenced by environmental factors. effects can contribute to phenotypic variation and adaption potentially impacting evolutionary processes across generations.

234
Q

What was the conclusion of the Duke mice experiment?

A

Analysis showed that the compounds in the vitamin supplements had triggered DNA methylation, which reduced the expression of the agouti gene responsible for the yellow coat and obesity.

235
Q

explain how smoking can affect individuals in an environmental way

A

exposure to cigarette smoke can create lasting effects on the gene expression (smoking creates environment that induces epigenetic changes which can be stable and passed thru gens.

236
Q

explain how smoking can affect individuals in an epigenetic way

A

methylation patterns established by grandmothers who smoked while pregnant can be inherited by her daughter then her grandchildren. genes related to asthma susceptibility can be turned on/off due to inherited methylation patterns

EX: smoking causes methylation patterns that suppresses gene involved in lung development or immune response, these changes can increase likelihood of asthma in grandchildren