Exam 1 - Ch. 8 Flashcards
methods for the movement of solutes
simple diffusion
facilitated diffusion
active transport
methods for bulk movement
exocytosis
endocytosis
membrane potential
electrical force across a membrane created ion gradients
-70mV
Ion movement based on electrochemical potential
moving in the same direction = no energy required
moving in opposite direction = energy required
electrochemical potential
sum of the concentration gradient & the charge gradient across the membrane
simple diffusion
unassisted movement of a solute from a [high] to a [low]
no energy required
small, nonpolar molecules
linear rate
osmosis
diffusion of water across a selectively permeable membrane
water moves toward high [solute]
hypertonic vs hypotonic solution
hypertonic - more solute outside of cell; water moves out
hypotonic - less solute outside of cell; water moves in
facilitated diffusion
transport proteins in the membrane provide a path for large molecules to diffuse across the membrane
no energy required
carrier proteins
bind solute then move them to another side of membrane after conformational change
usually high specificity
carrier protein transport types
uniport = 1 solute at a time symport = solutes move in same direction antiport = solutes move in opposite direction
channel proteins
form a hollow pathway to allow passage of the solute w/o a major change in conformation
ion channels
porins
aquaporins
ion channels
- voltage gated: respond to membrane potential
- ligand gated: respond to binding of ligand
- mechanosensitive channel: respond to mechanical forces
active transport
transport molecule against the concentration gradient
requires energy input
“pumps”
direct active transport
the accumulation of the solute molecule on one side of the membrane and the hydrolysis of ATP provides energy to move the molecule
Na+/K+ pump