Exam 1 Ch 54 Cancer Chemotherapy

Question 1

What are the different types of anticancer drug classifications? There are 6.

From Anticancer Agents Lecture

Answer 1

1) Alkylating Agents
2) Antimetabolites
3) Natural Products
4) Antitumor Antibiotics
5) Miscellaneous
6) Hormonal

Question 2

Which 2 drugs are categorized under the Alkylating Agents of anticancer agents?

From Anticancer Agents Lecture

Answer 2

1) Cyclophosphamide

2) Cisplatin

Question 3

What 5 drugs are categorized under Antimetabolites of anticancer agents?

From Anticancer Agents Lecture

Answer 3

1) 5-Fluorouracil
2) Methotrexate
3) Gemcitabine
4) 6-mercaptourine
5) 6-Thioguanine

Question 4

Which seven drugs did we learn are derived from natural products?

From Anticancer Agents Lecture

Answer 4

Vinka alkaloids:
1) Vinblastine
2) Vincristine
3) Vinorelbine
Podophyllotoxins:
4) Etoposide
Camptothecins
5) Irinotecan
Taxanes
6) Paclitaxel
7) Docetaxel

Question 5

What are 3 drugs are categorized under Antitumor Antibiotics of anticancer agents?

From Anticancer Agents Lecture

Answer 5

1) Bleomycin
2) Dexorubicin
3) Mitomycin

Question 6

What are the 2 drugs categorized under Miscellaneous of anticancer agents?

From Anticancer Agents Lecture

Answer 6

1) Imatinib

2) Cetuximab

Question 7

What are the 2 drugs categorized under Hormonal of anticancer agents?

From Anticancer Agents Lecture

Answer 7

1) Prednisone

2) Tamoxifen

Question 8

What do antimetabolites do?

Answer 8

Interfere with availability of normal purine or pyrimidine nucleotide precursors by 1) inhibiting their synthesis or 2) competing with them in DNA/RNA synthesis. Also have immunosupressant actions