Exam 1 Flashcards
Neurons
The functional unit of the nervous system
Composed of: Dendrites, Cell body, Axons
Dendrites
Sensory information carried TORWARD cell body (afferent)
Cell body
Interprets information
Axons
Carries action potential AWAY from cell body (efferent)
Neuroglial Cells
Non-neuronal cells which maintain homeostasis, form myelin, and provide support and protection for neurons
CNS: Astrocytes (BBB), ependymal cells (CSF), oligodendrocytes (myelin sheath)
PNS: Neurolemmocytes- Schwann cells (myelin sheath) Satellite cells- Microglial cells (macrophage)
Myelin
Multi-layered lipid and protein covering around some axons
Fx- Insulation, salutatory conduction
Present on axons (White matter)
Not present on all cell bodies, dendrites, terminals, and neuroglia (gray matter)
Sensory
To sense changes in the internal and external environments and send information to CNS Dendrites Afferent neurons (TOWARDS brain)
Integrative
Decides if a response is necessary based on incoming information
Cell bodies
Association neurons
Motor
Send an action potential (motor response) to the appropriate effector to produce the response
Axons
Efferent neurons (AWAY from the brain)
Central Nervous System
Brain
Spinal cord
Peripheral Nervous System
Cranial nerves
Spinal nerves
Action Potential Stages
- Resting state
- Depolarization
- Repolarization
- Hyperpolarization
* All or nothing response*
Resting State (salty banana)
Neuron is not being stimulated
More Na+ outside and more K+ inside
Membrane is polarized (more + outside)
-70 millivolts (intracellular)
Depolarization
Contraction
If stimuli increases membrane potential to -55 millivolts:
Sodium channels open in the membrane and sodium rushes into the cell thus increasing potential up to 30+ millivolts
Repolarization
“Reset”, relaxation
When membrane potential reaches 30+ millivolts:
Sodium channels close and Potassium channels open
(more + outside)
Potassium rushes out of the cell thus returning membrane potential to -70 millivolts
Hyperpolarization
Membrane voltage temporarily decreases to -90 millivolts
Potassium channels remain open for a short period after -70 millivolts has been reached
Resting Membrane Potential
Is re-established when the sodium/potassium pump, pumps 3 sodium ions OUT of the cell and 2 potassium ions IN the cell
Approx. 40% of the ATP’s produced by the neuron is used to drive the pump
Refractory Periods
Absolute: During depolarization + repolarization the neuron can NOT respond to additional information
Relative: During hyperpolarization, neuron can respond if stimulus is large enough to drive potential up to -55 millivolts
Synapse
A junction between 2 neurons or between a neuron and its effector
Excitatory Neurotransmitter
Drives post-synaptic membrane potential towards threshold (more positive)
- Acetylcholine @ neuromuscular junction
- Epinephrine/Norepinephrine during fight or flight
- Dopamine