Exam 1 Flashcards

1
Q

list the skeletal muscle components from inner-most to outer-most structures

A
myofilament
myofibril
myofiber
fascicle 
whole muscle
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2
Q

list the connective tissue within the skeletal muscle from inner-most to outer-most layers

A

endomysium
perimysium
epimysium

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3
Q

what is the muscle cell?

A

myofiber

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4
Q

name the neurotransmitter that is released into synapses between adjacent motor neurons

A

norepinephrine

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5
Q

explain one situation in which ATP is needed during a skeletal muscle contraction

A

ATP allows for the myosin head to achieve the cocked position needed for the power stroke to occur

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6
Q

a change in cell membrane potential of greater than 15-20mV is called a(n):

A

action potential

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7
Q

in comparison to type II muscle, type I fibers would have a higher concentration of:

A

isocitrate dehydrogenase

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8
Q

what accounts for the less forceful contraction from a type I muscle fiber?

A

myosin ATPase is less abundant than in type II
the sarcoplasmic reticulum is less developed than in type II fibers
fewer active sites for which the myosin head can bind are revealed per AP than in type II

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9
Q

during the propagation of the AP, potassium leaves the cell during:

A

repolarization

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10
Q

which neurotransmitter is required for proper activation of the skeletal muscle at the level of the neuromuscular junction?

A

acetylcholine (ACh)

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11
Q

describe the steps of the sliding filament theory in the correct order

A
  1. action potentials spread across the sarcolemma
  2. down t-tubules
  3. calcium is released
  4. the active site for the myosin head is revealed
  5. muscle shortens
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12
Q

which skeletal muscle fiber type is the most fatigue resistant?

A

type I

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13
Q

a motor neuron and all fo the muscle fibers it innervates is known as:

A

the motor unit

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14
Q

which skeletal muscle fiber type has the largest motor unit, and the most developed sarcoplasmic reticulum development?

A

type II

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15
Q

what is typically the most abundant energy substrate within the body?

A

fat

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16
Q

in which state does the muscle have the capacity to generate the greatest amount of force?

A

eccentric

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17
Q

proteins are broken down via oxidation and enter these processes at the level of the:

A

Krebs cycle

18
Q

which energy system has a SLOWER rate of energy synthesis?

A

beta oxidation

19
Q

at REST, the substrate utilized to provide the body with energy is determined by:

A

mass action effect

20
Q

what can be considered a rate limiting enzyme for the breakdown of glucose?
(think about what enzymes are used in glycolysis)

A

hexokinase (HK)

phosphofructokinase (PFK)

21
Q

when the ratio of CO2 expired to O2 utilized is at or above 1, an individual is utilizing __________ as their primary energy source.

A

glucose/glycogen

22
Q

the PCr reaction takes place within:

A

the cytosol of the cell

23
Q

the ETC reaction takes place within:

A

the mitochondria of the cell

24
Q

an individual is performing HIGH INTENSITY running intervals. what happens to the lactic acid that is produced during this workout?

A

70-75% of lactate is utilized as an energy source

it is shuttled to the liver and concerted into glucose via the Cori cycle

25
Q

which energy system is dominant in high intensity running intervals?

A

glycolysis

26
Q

you are participating in the polar plunge. as the even announcer gives the “start” signal to your group, you sprint to the water, submerge yourself, and sprint right back out taking only about 15 seconds. What is the dominant energy substrate during this event?

A

PCr

27
Q

which skeletal muscle fiber type is most likely to rely the LEAST on FFA’s for energy?

A

type I

28
Q

during times when glucose or glycogen availability is LOW, what can be utilized as an energy substrate by the brain and CNS?

A

ketone bodies

29
Q

breakdown of the triglyceride

A

lipolysis

30
Q

breakdown of the FFA

A

beta-oxidation

31
Q

breakdown of ATP into inorganic phosphate and ADP

A

hydrolysis

32
Q

formation of glucose from non-carbohydrate sources

A

gluconeogenesis

33
Q

breakdown of stored glycogen

A

glycogenolysis

34
Q

breakdown of glucose/glycogen

A

glycolysis

35
Q

formation of glycogen

A

glycogenesis

36
Q

what is the energy system that would be utilized for the majority of a 20-minute walk at low intensity?

A

oxidation of fat/beta-oxidation

aerobic

37
Q

what is the energy system that would be utilized for the majority of an 800-m (1/2 miil) race?

A

glycolytic system

anaerobic

38
Q

what is the energy system that would be utilized for the majority of a 45 minute run at moderate intensity?

A

oxidation of carbs until your body does not have any carbs readily available, then it would switch over to fats/beta-oxidation

39
Q

rank the energy systems from fastest to slowest

A

ATP-PCr
Glycolytic
Oxidation of carbs
Oxidation of fats

40
Q

rank the energy systems from most ATP produced to least ATP produced

A

oxidation of fats
oxidation of carbs
glycolytic
ATP-PCr

41
Q

explain why there are differences in energy produced when breaking down carbohydrates aerobically verses breaking down fats aerobically (oxidation).

A

42
Q

what are the components of actin/what is attached to the actin to allow SFT to happen?

A

troponin
tropomyosin
nebulin
more??