Exam 1 Flashcards

1
Q

list the skeletal muscle components from inner-most to outer-most structures

A
myofilament
myofibril
myofiber
fascicle 
whole muscle
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2
Q

list the connective tissue within the skeletal muscle from inner-most to outer-most layers

A

endomysium
perimysium
epimysium

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3
Q

what is the muscle cell?

A

myofiber

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4
Q

name the neurotransmitter that is released into synapses between adjacent motor neurons

A

norepinephrine

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5
Q

explain one situation in which ATP is needed during a skeletal muscle contraction

A

ATP allows for the myosin head to achieve the cocked position needed for the power stroke to occur

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6
Q

a change in cell membrane potential of greater than 15-20mV is called a(n):

A

action potential

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7
Q

in comparison to type II muscle, type I fibers would have a higher concentration of:

A

isocitrate dehydrogenase

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8
Q

what accounts for the less forceful contraction from a type I muscle fiber?

A

myosin ATPase is less abundant than in type II
the sarcoplasmic reticulum is less developed than in type II fibers
fewer active sites for which the myosin head can bind are revealed per AP than in type II

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9
Q

during the propagation of the AP, potassium leaves the cell during:

A

repolarization

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10
Q

which neurotransmitter is required for proper activation of the skeletal muscle at the level of the neuromuscular junction?

A

acetylcholine (ACh)

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11
Q

describe the steps of the sliding filament theory in the correct order

A
  1. action potentials spread across the sarcolemma
  2. down t-tubules
  3. calcium is released
  4. the active site for the myosin head is revealed
  5. muscle shortens
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12
Q

which skeletal muscle fiber type is the most fatigue resistant?

A

type I

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13
Q

a motor neuron and all fo the muscle fibers it innervates is known as:

A

the motor unit

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14
Q

which skeletal muscle fiber type has the largest motor unit, and the most developed sarcoplasmic reticulum development?

A

type II

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15
Q

what is typically the most abundant energy substrate within the body?

A

fat

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16
Q

in which state does the muscle have the capacity to generate the greatest amount of force?

A

eccentric

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17
Q

proteins are broken down via oxidation and enter these processes at the level of the:

A

Krebs cycle

18
Q

which energy system has a SLOWER rate of energy synthesis?

A

beta oxidation

19
Q

at REST, the substrate utilized to provide the body with energy is determined by:

A

mass action effect

20
Q

what can be considered a rate limiting enzyme for the breakdown of glucose?
(think about what enzymes are used in glycolysis)

A

hexokinase (HK)

phosphofructokinase (PFK)

21
Q

when the ratio of CO2 expired to O2 utilized is at or above 1, an individual is utilizing __________ as their primary energy source.

A

glucose/glycogen

22
Q

the PCr reaction takes place within:

A

the cytosol of the cell

23
Q

the ETC reaction takes place within:

A

the mitochondria of the cell

24
Q

an individual is performing HIGH INTENSITY running intervals. what happens to the lactic acid that is produced during this workout?

A

70-75% of lactate is utilized as an energy source

it is shuttled to the liver and concerted into glucose via the Cori cycle

25
which energy system is dominant in high intensity running intervals?
glycolysis
26
you are participating in the polar plunge. as the even announcer gives the "start" signal to your group, you sprint to the water, submerge yourself, and sprint right back out taking only about 15 seconds. What is the dominant energy substrate during this event?
PCr
27
which skeletal muscle fiber type is most likely to rely the LEAST on FFA's for energy?
type I
28
during times when glucose or glycogen availability is LOW, what can be utilized as an energy substrate by the brain and CNS?
ketone bodies
29
breakdown of the triglyceride
lipolysis
30
breakdown of the FFA
beta-oxidation
31
breakdown of ATP into inorganic phosphate and ADP
hydrolysis
32
formation of glucose from non-carbohydrate sources
gluconeogenesis
33
breakdown of stored glycogen
glycogenolysis
34
breakdown of glucose/glycogen
glycolysis
35
formation of glycogen
glycogenesis
36
what is the energy system that would be utilized for the majority of a 20-minute walk at low intensity?
oxidation of fat/beta-oxidation | aerobic
37
what is the energy system that would be utilized for the majority of an 800-m (1/2 miil) race?
glycolytic system | anaerobic
38
what is the energy system that would be utilized for the majority of a 45 minute run at moderate intensity?
oxidation of carbs until your body does not have any carbs readily available, then it would switch over to fats/beta-oxidation
39
rank the energy systems from fastest to slowest
ATP-PCr Glycolytic Oxidation of carbs Oxidation of fats
40
rank the energy systems from most ATP produced to least ATP produced
oxidation of fats oxidation of carbs glycolytic ATP-PCr
41
explain why there are differences in energy produced when breaking down carbohydrates aerobically verses breaking down fats aerobically (oxidation).
--
42
what are the components of actin/what is attached to the actin to allow SFT to happen?
troponin tropomyosin nebulin more??