Exam 1 Flashcards
What are the 4 parts of the care process?
Assessment
Diagnosis (PES)
Intervention
Monitoring
What are some risk factors that would affect a patients nutritional intake
Food/nutrient intake (inadequate intake, GI issues)
Physical (overweight, age, CA, neurologic impairment)
Psychological/social factors (low income, depression, addictions)
Biochemical/meds (abnormal lab work, chronic med use/poly pharmacy)
What is the MUST tool used for? And PG-SGA?
Determining risk of malnutrition
0- routine care
1- observe
2 or more is high risk- treat
5 components of a nutritional assessment
Screen Health history Med/supplement use Social history Diet history
Diet history information
Allergies to food Appetite Necessary dietary modifications GI issues Who does the shopping Physical activity Concerns of the patient
What are 3 ways you can get a nutrient intake from a patient
24 hour recall
Food diary
Food frequency questionnaire (FFQ)
Static assay vs. functional assay
Static: measurement of nutrient in blood, urine or tissue. Ex: vitamin A
Functional: measurement of a process requiring specific nutrients ex: bone density scans for calcium/vitamin D
Issues with biochemical assessment
Assessment can be influenced by non-nutritional factors ex: environment, disease
No test thats sufficient for monitoring nutritional status
Some non-specific
What is stool testing good for
Fat malabsorption
GI flora
Blood
Pathogens
-fecal occult blood test with unexplained anemia
What are some cytokine bio markers
IL-1B
TNF-a
IL-6
What do cytokines and eicosanoids do?
Increase muscle breakdown and cause redistribution of plasma protein that leads to edema
decrease production of RBS
Pull iron away from hemoglobin to ferritin
Inhibits transferrin
Lab tests for anemia during inflammation
Lab tests for anemia are not reliable when inflammation is present
Positive acute phase reactants during inflammation
C reactive protein Fibrinogen Ferritin Ceruloplasmin Alpha-1-antitrypsin
INCREASED
Negative acute phase reactants and inflammation
- albumin (looks like protein deficiency)
- transferrin
- prealbumin
- retinol-binding protein
Microcytic anemia
Hypochromic anemia
Iron deficiency or copper
Macrocyclic anemia
Megaloblastic anemia
Folate or B12 deficiency
Assess for microcytic (iron deficiency) anemia
Hematocrit (% RBC in blood) Hemoglobin Ferritin (iron storage in liver) Serum iron Total iron binding capacity Transferrin saturation (iron availability to tissues)
Assessment to microcytic anemia
Folate
B12
Methylmalonic acid (MMA) —differentiates between B12/folate deficiency. Best for b12
Serum homocysteine
What is the long-term marker for blood glucose control
Hemoglobin A1C
Hemoglobin A1C
Long-term blood sugar control. Averages the last 2-3 months.
Abnormal >6.4%
Each 1% increase = increase of 35mg/dl in blood sugar
What is normal blood glucose fasting value
70-99mg/dL
Markers of oxidative stress
Antioxidants: C & E SE Phytochemicals (carotenoids) AOX/enzymes -superoxide mutate, catalase, glutathione
Potential biomarkers of oxidative stress
- *F2 isoprostates
- *Myeloperoxidase (MPO)
- MDA
- oxidized LDL
- MPO
- ROS
- serum antioxidant capacity
Best way to measure Vitamin D
Calcidiol
BMI severe thinnness
BMI moderate thinness
<16
16.0-16.9
BMI for mild thinness and normal range
- 0-18.49
18. 5-24.9
BMI for overweight and preobese
25+
25-29.9
BMI for three obese classes
1: 30-34.9
2: 35-39.9
3: 40+
Better indications of body weight than BMI
Waist circumference
waist: hip ratio
Waist circumference in men and women that is healthy
Men: under 40 inches
Women: under 35 inches
Wait: hip ratio in men and women that is healthy
Men: under 0.95
Women: under 0.8
Healthy wait to height recommendations for men and women
Men: 0.43-0.53
Women: 0.42-0.49
Underweight waist to height ratio for males and females
Under 0.35