Exam #1& #2: Microbiology Flashcards
SHORT ANSWER
What is active immunity?
Acquired by infection or vaccination
Who developed the “germ theory of disease?”
Louis Pasteur
Vaccination is what is an example of what kind of immunity?
Artificial active immunity
SHORT ANSWER
What is passive immunity?
Transfer of antibodies through serum or another individual. (Mother/infant)
What was FIRST developed in 1595 by Zacharias Jansen?
Compound light microscope
Compound light microscope
- Also called “Bright field”
2. Has a two lens system
Dark Field Microscope
- Opaque disc that blocks direct light
2. Unitized when microbes cannot be stained
What Contains ring shape diaphragm that allows light of various brightness to pass through highlighting the internal structures of the cell?
Phase Contrast Microscope
Fluorescence Microscope
- Utilizes ultraviolet light
2. Useful in identification of rabies and syphilis
Electron Microscope
- Utilizes a beam of electrons on place of light which improves resolution
- Utilizes an electro magnetic lens in place of a glass lens
What is the smallest living unit within the body; on average there are approximately 75-100 trillion cells in the human body?
Cell
SHORT ANSWER
What regulates transport of substances into and out of the cell?
Cell membrane
SHORT ANSWER
What functions does the cytoplasm have?
replication, growth and expansionary carried out in the cell
SHORT ANSWER
What serves as the “brain” for the control of the cell’a metabolic activities and cell division?
Nucleus
What contains DNA?
Nucleus
What cytoskeleton structure and extra cellular matrix control, in large part, the cell shape?
Mitochondria
SHORT ANSWER
What serves as sites for cellular respiration and energy production; stores ATP?
Mitochondria
What is responsible for protein packing?
Golgi Apparatus/ Golgi Complex
SHORT ANSWER
What serves as sites for protein synthesis?
Ribosomes
SHORT ANSWER
Passive transport
- Involves carriers, channels or direct diffusion through a membrane.
- Always operates from regions of greater concentration to regions of lesser concentration.
- No external energy is required
SHORT ANSWER
Active transport
- Is possible to go against the concentration gradient
- A source of energy is required to move carriers & it’s materials
- ATP is required
SHORT ANSWER
What are 5 classes of microorganisms & an example of each?
- Protozoa- malaria
- Fungi- mushroom
- Bacteria- tetanus
- Viruses- AIDS
- Prions- kuru
What is divided by a process called binary fission?
Bacteria
What are long, thin structures attached to the outside of the cell which uses a whipping motion to provide motility to the cell?
Flagella
What microorganisms are capable of producing disease under favorable condition?
Pathogen
When do organisms benefit and the host is harmed?
Parasitism
When both organisms benefits and dependent a one another to a certain extent?
Mutualism
What are rod shaped cells?
Bacilli
What is found in the intestines and produce vitamin K?
Escherichia coli (E. Coli)
What are chains of spherical bacteria?
Streptococci
What are normal resident flor on skin?
Staphylococcus aureus
What is the most commonly transmitted bacteria in the OR?
Staphylococcus aureus
What habitually live in the epidermis, deep in the crevices and folds of the skin?
Staphylococcus aureus
SHORT ANSWER
How is a virus replicated?
The virus ATTACHES to host cells/ receptors on the capsomere; then PENETRATES cytoplasmic (outside) membrane or through receptor mediated endocytosis. Viral nucleic acid is FREED and viral replication begins.
What are spiral shaped rods?
Spirilla
What is transmitted by insect bites?
Arthropod vectors
What causes Rocky Mountain fever?
Rickettsia rickettsii
What are viral genetic material?
DNA & RNA (usually not both)
What are ALL fatal because the immune system does not recognize proteins as foreign & protection does not develop?
Prions Disease
What attacks the brain & eventually kill the neuron? The death of the neuron creates holes in the brain tissue.
Prion Disease
What are 3 facts for Prions?
- Simple protein
- Smaller than a virus
- Lacks a genome
What prion disease affects sheep?
Scrapie
What spreads through air by sneeze droplets?
Airborne
What is spread through oral/fecal hepatitis transmission; post operative cholecystectomy wound infection from contact w/PT’s gallbladder?
Direct Contact
What infection is spread by contaminated surgical instruments?
Indirect Contact
What infection is carried in blood products?
Common Vehicle Spread
What are the 5 signs of inflammation?
- Redness
- Heat
- Swelling
- Pain
- Loss of function