Exam #1 Flashcards
carbon in biology
the framework of biological molecules consists primarily of carbon bonded to:
* another carbon
* O, N, S, P, and H
can form 4 covalent bonds
hydrocarbons
- molecule consisting only of carbon and hydrogen
- HYDROCARBONS ARE NONPOLAR
Isomers and the 2 types
- molecules with the same molecular/empirical formula (which means that they have the same # of atoms)
1. structural isomers
2. stereoisomers: differ in how groups are attached
enantiomers
mirror image molecules = chiral
example: D-sugars
define polymer
built by linking monomers
define monomer
small, similar chemical subunits
monomer for carbohydrates
monosaccharide
monomer for nucleic acid
nucleotide
monomer for protein
amino acid
dehydration synthesis
- formation of large molecules by the removal of water
- monomers are joined to form polymers
hydrolysis
- breakdown of large molecules by the addition of water
- polymers are broken down to monomers
carbohydrates
- molecules with a 1:2:1 ratio of C, H, O
- CH2O
- C-H hold much energy
- Carbs are good energy storage
- example: sugars, starch
Monosaccharides
- simplest carbohydrate
- 6 carbon sugars are important
glucose
C6H12O6
* fructose is a structural isomer of glucose
* galactose is a stereoisomer of glucose
Disaccharides
- 2 monosaccharides linked together by dehydration synthesis
- used for sugar transport or energy storage
- sucrose, lactose, maltose
polysaccharides
- long chains of monosaccharides (linked thru dehydration synthesis)
- energy storage (plants use starch)
- structural support (plants use cellulose)
nucleic acids
name polymer and monomer
polymer: nucleic acids
monomers: nucleotides
* nucleotides are connected by phosphodiester bonds
nitrogenous bases include:
purines: adenine and guanine
pyrimidines: thymine, cytosine and uracil
deoxyribonucleic acid (DNA)
- encodes information for amino acid sequence of proteins
- base-pairing rules:
A with T (or U in RNA)
C with G
define double helix
2 polynucleotide strands connected by hydrogen bonds
ATP
adenosine triphosphate
- primary energy currency of the cell
ribonucleic acid (RNA)
- single polynucleotide strand
- RNA uses info in DNA to specify sequence of amino acids in proteins
DNA vs RNA
DNA
* contains deoxyribose
* contains thymine
* double stranded sugar phosphate
RNA
* contains ribose
* contains uracil
* sigle stranded sugar phosphate
NAD+ and FAD+
- nicotinamide adenine dinucleotide
- flavin adenine dinucleotide
- electron carriers for many cellular rxns
the 7 protein functions:
- enzyme catalysis
- defense
- transport
- support
- motion
- regulation
- storage
protein
- proteins are polymers
- composed of 1 or more long, unbranched chains
- amino acids are monomers
- amino acids are joined by dehydration synthesis
- peptide bond
1st and 2nd levels of protein structure
shape of protein = its function
1. primary: sequence of AA
2. secondary: interaction of groups in the peptide backbone
* alpha helix
* beta helix
3rd and 4th levels of protein structure
- tertiary: final folded shape of a globular protein
- stabilized by a number of forces
- final level of structure IF protein only consists of a single polypeptide chain - quaternary: arrangement of individual chains (subunits) in a protein with 2 or more polypeptide chains
motifs
additional structural characteristics
- common elements of secondary structure seen in many polypeptides
- useful in determining the function of unknown proteins
domains
additional structural characteristics
- functional units within a larger structure
- most proteins made of multiple domains that perform different parts of the protein’s function
chaperone proteins
- chaperone proteins help protein fold correctly
- deficiencies in chaperone proteins implicated in certain diseases
- cystic fibrosis (protein fails to fold)
define matter
- matter has mass and occupies space
- all matter is composed of atoms