exam 1 Flashcards
explains behavior from a biological and chemical point of view
psychobiologists seek to discover the relationships between behavior an the underlying physiological mechanisms
psychobiology
the stereotaxic instrument is utilized for proper placement of an electrode or cannula
an animal is anesthetized and then placed on the stereotaxic instrument- an electrode or cannula is permanently implanted into the brain
stimulation technique for studying the brain
a wire is connected to the electrode- weak electrical currents are passed through the wire
electrical stimulation
a cannula is placed in the brain, cannula may be metal (guide cannula) with thinner plastic tubing inserted into guide cannula or a hypodermic needle- chemical administered through the cannula
chemical stimulation
micro electrode recording from a single cell, EEG, electroencephalogram, gross electrical recording from a large brain area
electrical recording techniques
a stereotaxic instrument is deployed and part of the brain is removed, damaged, destroyed, or inactivated, then the behavior of the subject is carefully assessed
lesion method
sucking out tissue
aspiration lesions
burning the tissue
radio-frequency lesions
leucotome is stereotaxically positioned in the brain, then the blade swings out to make a cut (frontal lobotomy)
knife cuts
cooling a target area or injecting an anesthetic into the area
reversible lesions
animal is sacrificed at the end of the experiment
- brain is removed, placed in formalin, embedded in paraffin
- brain is then slice, stained, and examined
histological examinations
contrast x-ray technique that reveals blood vessels in the brain
before x ray is taken a radio-opaque dye is injected into the blood vessels that enter the brain
angiogram
individual images are obtained by passing x-rays through the head
a narrow x-ray beam is emitted by a source on one side of the head and a detector measures the number of x-ray photons that emerge on the other side
similar to conventional x-ray but many different sections through the brain are obtained
computerized axial tomography (cat scan)
similar to cat scan, but the signal arises from the decay of a radioisotope that has been injected into the patients circulation
a distinct advantage of this is the radioisotope (radioactive fluorodeoxyglucose) can be linked to glucose, the principal metabolic fuel of the brain
STUDYS FUNCTION
positron emission tomography (pet) scan
advantage is taken of the fact that the nuclei of atoms in the brain respond to magnetic field differentially, depending on their local atomic environment
by exposing the head to magnetic fields of different strengths, the computer assisted 3D image of the brain is made
magnetic resonance imaging (MRI)
combines structure and function
utilizes high powered, rapidly oscillating magnetic fields and powerful computation to measure the cerebral blood flow in the brain and obtain a measure of neural activity in the brain
produces images of the increase in oxygen flow in the brain to active areas of the brain
fMRI (functional magnetic resonance imaging)
this is a pattern recorded by electrodes from a specific part of the brain in response to a stimulus such as sight, sound, or touch
record how quickly and completely the nerve signals reach the brain and can indicate problems along nerve pathways that are too subtle to show up during a neurological examination or be noticed by the patient
evoked response potential (ERP)
receiving end, specialized for excitation
dendrites
controls metabolism of the cell
cell body (soma)
delivers impulses, specialized for conduction
Axon
area between cell body and axon of a neuron
axon hillock
a swelling at the end of an axon
terminal button
fatty insulation around many axons, aids in conduction, its found on neurons inside and outside of the CNS, nerve cells with this conduct faster than nerve cells without, its interrupted at regular intervals by the nodes of Ranvier
myelin sheath
inside of the CNS: astrocytes and oligodendrocytes
-provide nourishment for neurons
-provide support for neurons
-protect and insulate axons
-lay down the myelin sheath
satellite cells
outside of the CNS, in the peripheral nervous system
-protect and insulate neurons
- lay down myelin sheath
-involved in regeneration of damaged nerve fibers
schwann cells
this is found in sensory nerves sub serving somethesis (pain, touch, temperature, pressure) and kinesthesis (limb position)
axon is connected via a little neck to the cell body
unipolar neuron
found in the eye
connected directly to the cell body
bipolar neuron
this type is found in motor nerves
consists of a single long axon and a number of dendrites
motor neuron (multipolar neuron)
this is located predominantly in the spinal cord and brain and is the most numerous of all types of neurons in the nervous system
found in between other neurons
interneurons (multipolar neuron)
has a short, multibranching dendrites and a long axon, a structure that makes it ideally suited for transmitting information over long distances within CNS
projection neuron
axons of this area noticeably short and both its axons and dendrites show profuse branching (this enables it to establish multiple relations with other neurons)
typically receives information from a large number of sensory neurons or other interneurons and delivers information to a large number of motor neurons or other interneurons
local circuit neuron
towards head
rostral
towars tail
caudal
above a structure
superior
below a structure
inferior
towards midline
medial
away from midline
lateral
toward midline
proximal
away from midline
distal
front
anterior
back
posterior
base of brain, front
ventralback,
top of brain, back
dorsal
sensory
afferent
motor
efferent
bundles of neurons located outside of CNS
nerve
bundle of neurons located inside of CNS
tract
collection of nerve cell bodies located outside of CNS
ganglion
collection of nerve cells located inside of CNS
nucleus
12 pairs of these located inside the somatic nervous system which is located inside the peripheral nervous system
cranial nerves
- olfactory
- ent./exit from CNS- cerebrum
- no autonomic functions
- sensory: smell
-not a real nerve
cranial nerve I
- optic
- ent./exit from CNS- thalamus
- no autonomic function
- sensory: vision
- not a real nerve
cranial nerve II
- oculomotor
- exit from CNS- midbrain
- autonomic function: constricts pupils
- motor: eye movement, down and in
cranial nerve III
- trochlear
- exit from CNS- midbrain
- no autonomic function
- motor: eye movement up and out
cranial nerve IV
- trigeminal
- ent.&exit from CNS- midbrain, pons, medulla
- no autonomic function’
- sensory: from face & head
- motor: chewing
cranial nerve V
- abducens
- exit: pons and medulla
- no autonomic function
- motor: eye movement laterally
cranial nerve VI
- facial
- exit and ent.: medulla
- crying, accommodation, salivation
- sensory: taste (anterior 2/3 of tongue)
- motor: face movement
cranial nerve VII
- auditory-vestibular
- ent.: medulla
- no autonomic function
- sensory: hearing/balance
cranial nerve VIII
- glossopharyngeal
- ent from CNS- medulla
- autonomic function: salivation
- sensory: taste 1/3 back of tongue
- motor: pharynx/speech
cranial nerve IX
- vagus
- exit/ent.: medulla
- autonomic function: heart, viscera, blood vessels
- sensory: taste (pharynx and epiglottis)
- motor: swallowing, pharynx, speech
cranial nerve X
- spinal accessory
- exit from CNS- medulla
- no autonomic function
- motor: neck muscles/speech
cranial nerve XI
- hypoglossal
- exit from CNS: medulla
- no autonomic function
- motor: tongue movement
cranial nerve XII
cranial nerves ___ through ___ are peripheral nerves- regeneration takes place
3-12
cranial nerves ___, ___, and ___ work together they’re concerned with eye movement
III, IV, and VI
cranial nerve ___ is the big parasympathetic nerve
cranial nerve X
8 pairs positioned in the neck
cervical
12 pairs positioned in the chest
thoracic
5 pairs positioned in the loin (trunk)
lumbar
5 pairs positioned at the end of spinal column
sacral
1 pair positioned at the end of the spinal column
coccygeal
the ___ ___ of the spinal nerve receives input from receptor
dorsal root
the ___ ___ of the spinal nerve sends output to effectors
ventral root
just before entering the vertebral column, the spinal nerves divide into __ roots
2
the ___ ___ is sensory
dorsal root
the __ ___ is motor
ventral root
on each dorsal root there is a marked swelling, the ___ ___ ___, that contains the cell bodies of the sensory fibers (unipolar neurons)
dorsal root ganglion
inside the spinal cord itself are the cell bodies of the motor fibers, which are also called ____ ____
multipolar neurons
- sensory and motor activities
- connections found within CNS
- differentiation
- distributed to skeletal muscles
- adjusts between external environment and the organism
somatic nervous system
- motor system only
- many synapses/ganglia lie outside of CNS
- acts as a whole
- distributed to smooth/cardiac muscles
- concerned with internal adjustments
autonomic nervous system
- afferent component
- enters dorsal root of spinal nerves of somatic nervous system
visceral nervous system
- efferent component
- under the influence of the hypothalamus
autonomic nervous system
- places of exit from CNS in thorax and lumber regions of spinal cord= thoracolumbar nervous system
- mobilizes bodily resources “fight or flight”
sympathetic nervous system
- goes from spinal cord (lateral horn) to sympathetic chain
- relatively short
- secretes acetylcholine (ACH)
preganglionic fiber of spinal cord from sympathetic fibers
- goes from sympathetic chain to organ to be innervated
- relatively long
- secretes norepinephrine (NE)
postganglionic fiber of spinal cord from sympathetic fibers
composed of 22 sympathetic chains
ganglia
consists of axons of preganglionic fibers (which are myelinated) from the point where they leave the ventral root to the point where they enter the sympathetic chain
white ramus
axons of postganglionic fibers (unmyleinated) from the point where they leave the sympathetic chain to the point where they enter the ventral root
gray ramus
- places of exit from the CNS: brain and sacral region of spinal cord= craniosacral nervous system
- conservation and storage of bodily resources, active after eating
parasympathetic nervous system
- goes from brain or spinal cord (lateral horn) to a collateral ganglion
- relatively long
- secretes acetylcholine (ACH)
preganglionic fiber of spinal cord from parasympathetic fiber
- goes from collateral ganglion to the organ to be innervated
- relatively short
- secretes acetylcholine (ACH)
postganglionic fiber of spinal cord from parasympathetic fiber
- causes the heart to beat faster
- constricts surface arteries and raises blood pressure
- dilates blood vessels to skeletal muscles
- speeds clotting
effects of sympathetic nervous system on circulatory system
- causes heart rate to slow
- inhibits constriction of surface arteries and lowers blood pressure
effects of parasympathetic nervous system on circulatory system
- facilitates breathing by dilating bronchioles
effects of sympathetic nervous system on respiratory system
- slows breathing by constricting bronchioles
effects of parasympathetic nervous system on respiratory system
- inhibits peristalsis of stomach and small intestine
- inhibits gastric secretion
- inhibits secretion of saliva
- effects of sympathetic nervous system on digestive system
- facilitates peristalsis of stomach and small intestine
- facilitates gastric secretion
- facilitates secretion of saliva
- effects of parasympathetic nervous system on digestive system
- inhibits action of bladder (relaxes muscle wall)
- vasoconstriction in kidney leading to decreased urine
- contracts uterus
effects of sympathetic nervous system on urinary genital system
- facilitates action of bladder (muscle wall contracted)
- vasodilation in kidney leading to increased urine flow
- relaxes uterus
effects of parasympathetic nervous system on urinary genital system
- dilates pupil
effects of sympathetic nervous system on eye
- constricts pupil
effects of parasympathetic nervous system on eye
stimulates secretion
effects of sympathetic nervous system on adrenal gland
secretion augmented
effects of sympathetic nervous system on sweat glands
pilomotor response (goosebumps)
effects of sympathetic nervous system on hair
secretes glucose (changes glycogen into glucose)
effects of sympathetic nervous system on liver
constricts and gives off red blood cells
effects of sympathetic nervous system on spleen
- conducts impulses to and from brain
- regulates reflexes
- has gray matter and white matter
spinal cord
place where fibers cross from one side of the spinal cord to the other side
gray commissure
- conduction paths or tracts
- divided into 3 types of columns
- dorsal, lateral, and ventral
white matter
between dorsal horn and dorsal fissure
dorsal column (afferent)
between dorsal horn and ventral horn
lateral column (mixed sensory and motor)
between ventral horn and ventral fissure
ventral columns (efferent)
- found in lateral area of white matter
- shorts tracts that connect different levels of spinal cord
ground bundles /intersegmental tracts
name of a tract, first: place it originates, second: places where it terminates
unconventional nomenclature
gracilis, cuneate
both sensory- kinesthesis
dorsal columns
dorsal spinocerebellar
ventrolateral spinocerebellar
both sensory- cerebellum
lateral column
- lateral column
- sensory- pain, temperature, diffuse light touch
lateral spinothalamic
- lateral column
- sensory- pressure, specific light touch
ventral spinothalamic
- lateral column
- motor- voluntary movement
lateral corticospinal
- lateral column
- motor- coordination of movement
rubrospinal, reitculospinal
- ventral column
- motor- voluntary movement
ventral corticospinal
- ventral column
- motor- coordination of movement
vestibulospinal
- joins spinal cord to the higher parts of the brain
- contains fiber tracts ascending/descending to various levels of CNS
- places of eat for a number of cranial nerves (V-XII)
-contains autonomic nuclei concerned with breathing, blood pressure, and heart beat
VITAL CENTER OF THE BRAIN
medulla
- contains fiber tracts ascending/descending to various levels of the CNS
- place of exit of cranial nerves V&VI entrance of cranial nerve V
- contains transverse fibers emerging from one side of the cerebellum and going across the ventral surface of the pons and entering the cerebellum on the other side
- has a complex of nuclei, pontine nuclei, within bands of transverse nuclei
pons
- ventral portion: receives fibers that have been relayed from the sense organs of equilibrium
- anterior portion, posterior portion: supplied chiefly with sensory fibers from spinal cord
- neoecerebellum: has extensive connections with nuclei of pons and frontal cortex
- organ of motor coordination
cerebellum
- connects forebrain and medulla
- tegmentenum (floor)- mainly passageway
- tectum (roof)- has sensory duties: two pairs of sensory centers
- 2 superior colliculi- primitive visual centers
- 2 inferior colliculi- primitive auditory
midbrain
the medulla, pons, and midbrain
brainstem
- overlaps forebrain, midbrain, and hindbrain
- ascending component: constitutes one of two routes traveled by sensory impulses on the way to the cerebral cortex- indirect sensory system
reticular formation
stimulus— nerve impulse—- specific part of cortex
direct sensory system
stimulus— nerve impulse— reticular formation— diffusely to the whole cortex
indirect sensory system
functions in motor coordination
descending component of reticular formation
contains the hypothalamus and thalamus
diencephalon
- all of the senses except for smell, send impulses to here on the way to the cortex
- great relay center of the brain
thalamus
- one of the relay (projection) nucleis
- responsible for somesthesis, kinesthesis, and taste
posteroventral nucleus (PVN)
- one of the relay nuclei
- part of the limbic system
anterior nucleus
impulses from the reticular formation
reticular nucleus
- one of the geniculate nuclei
- responsible for vision
lateral geniculate nucleus (LGN)
- 2/2 of the geniculate nuclei
- responsible for hearing
medial geniculate nucleus (MGN)
receives impulses from cerebellum and sends impulses to the cerebral cortex
lateroventral nucleus
- part of lateroventral nucleus
- receives impulses from within thalamus and send impulses to cortex
association nuclei
projects to the frontal cortex, fibers from this to the cortex are severed in a frontal lobotomy
dorsomedial cortex
projects to the posterior cortex
pulvinar nucleus
- involved in regulation of basic drives (hunger and thirst)
- controls and integrates functions of the autonomic nervous system
- involved in endocrine secretions
- involved in emotion
hypothalamus
- consists of 3 large nuclei
- receives input from substantial nigra to the cerebral cortex and sends messages to midbrain and cerebral cortex
- significant in maintaining posture of organism and coordination of movement
- phylogenetically they are the oldest part of the telencephalon
- degeneration of neurons with dopamine as neurotransmitter that link substania nigra to these leads to Parkinson’s disease
basal ganglia