Ex. 6 - Toothpaste Flashcards

1
Q

“powder for rubbing the teeth”

A

Dentrificum

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2
Q

This term came from the two words: Dentis (tooth) and fricare (to rub)

A

Dentrifices

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3
Q

T/F: Dentrifices are Agents used with a toothbrush to clean and polish the accessible surfaces of the teeth

A

true

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4
Q

T/F: The forms of dentrifices are pastes, powders, gels or liquid. However, the most important is the paste form because of its inherent consumer benefits, preferred dosage vehicle for special therapeutic and cosmetic agents.

A

True

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5
Q

Toothpaste: Functions

  • To provide special _______ effect
  • For teeth ________
  • To ______ breath
  • To ______ sensitivity of hypersensitive teeth
  • To reduce ______
  • To help prevent ______
  • To promote ______ health (anti-gingivitis)
  • To act as vehicles for abrasives to remove ____________
  • To act as ________ to introduce active agents into the oral cavity
A

cleaning; freshen; reduce; plaque; caries/tartar; gum; stain pellicle; vehicle

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6
Q

These substances are used to reduce the hypersensitive teeth

A

potassium nitrate and stannous fluoride

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7
Q

this powder has special cleaning effects

A

baking soda

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8
Q

is a biofilm or mass of bacteria that grows on surfaces within the mouth.

A

dental plaque

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9
Q

Removal of dental biofilm is important as it may become ______ causing ________________ of the teeth also known as _______, or harden into _______________ (also known as tartar).

A

acidic; demineralization; caries; dental calculus

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10
Q

T/F: the bacteria in the dental plaque feeds on sugar that produces the acid

A

True

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11
Q

This exerts mechanical cleansing effect. Helps remove stained pellicle. Acts in concert with the toothbrush.

A

Abrasive

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12
Q

T/F: Particle size of abrasives are largely below 0.4 mm in diameter

A

True

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13
Q

is a protein film that forms on the surface enamel by selective binding of glycoproteins from saliva that
prevents continuous deposition of salivary calcium phosphate

A

dental pellicle

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14
Q

This abrasive agent is a polishing agents which makes up 0.2 to 0.6% of volume of toothpaste. It is present in small fractions (less than 1/10 of the weight of the principal abrasive) and the particle size is 0.2 micrometers

A

Titanium

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15
Q

Insoluble phosphate, Dicalcium phosphate (dihydrate and anhydrous), calcium phosphate, sodium bicarbonate (baking soda) calcium carbonate (precipitated chalk), hydrated silica, silicon oxide, aluminum oxide, granular polyvinyl chloride

A

Abrasive

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16
Q

T/F: Typical dentifrices which have
significant consumer acceptability
are the toothpaste having a high
content of water-insoluble abrasive
such as dicalcium phosphate and sodium monofluorophosphate 0.2% in aqueous humectant base

A

True

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17
Q
  • Surface active agent
  • Has foaming and detergent properties
A

Foaming agent (surfactant)

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18
Q

sodium lauryl sulfate(SLS), sodium dodecylbenzene sulfonate, magnesium lauryl sulfate, sodium lauryl sulfoacetate, dioctylsulfosuccinate, sodium coconut monoglyceride sulfonate

A

Foaming agent (surfactant)

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19
Q
  • Imparts pleasant taste sensation (cooling)
  • Leave a residual freshness and cooling sensation
A

Flavoring agent

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20
Q

peppermint, spearmint, wintergreen, cinnamon, mint, thymol, menthol, clove oil, eucalyptol oil

A

Flavoring agent

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21
Q

T/F: Flavoring agents for children include special flavors, such as bubble gum and fruit aromas (mango, strawberry, apple, and banana)

A

True

22
Q
  • Sweetens the taste
  • Non fermentable sugar
A

Sweetening agent

23
Q

sodium saccharin (most widely used), sorbitol, mannitol, glycerin, acesulfame, aspartame

A

Sweetening agent

24
Q

Maintain moisture and consistency of paste by absorbing moisture from air

A

Humectant

25
Q

T/F: Humectants also provide a creamy base which resists drying out. It can also be a vehicle where other ingredients can be suspended or dissolved.

A

True

26
Q

T/F: Humectants are 15 to 80% of total vehicle

A

False. 5 to 35%

27
Q

glycerol, 70% sorbitol,PG, PEG, mannitol

A

Humectant

28
Q
  • Maintains the PASTY consistency of the preparation
  • Develops a cohesive structure with desired rheological properties
  • hydrophilic colloids that disperse and swell in the water phase
A

Binder/Gelling Agent/Thickeners

29
Q

synthetic cellulose derivatives (CMC,MC,HEC), alginates, gums, carrageenan or calcium, carrageenate, carbomer; polyacrylates, clays (both natural processed bentonite and
synthetic clays), precipitated silica

A

Binder/Gelling Agent/Thickeners

30
Q
  • to provide a pleasant appearance
A

Coloring agent

31
Q

mica, organic pigments, such as Blue 1and Red 33, Titanium dioxide (white color)

A

Coloring agent

32
Q

Prevents bacterial growth on binding agent

A

Preservative

33
Q

T/F: Toothpaste without ionic surfactants are formulated with preservatives (approx. 0.2% w/w) to prevent bacterial growth for long term storage

A

True

34
Q

sodium benzoate, dichlorophene, ethyl and methyl paraben; formaldehyde

A

Preservative

35
Q

Active agents
Whitening agents
Water

A

Special additives

36
Q

to provide therapeutic and/ or other special benefits

A

Active agents

37
Q

Active agents such as Fluoride compounds like _______________ or ______________ for effective control of dental caries and tooth decay

A

stannous fluoride; sodium fluoride

38
Q

This special additive assists in formulation

A

Water

39
Q

What type of toothpaste based on formulation that has a low abrasive level and high humectant level? This is also for people with high sensitivity

A

Type I

40
Q

What type of toothpaste based on formulation that has a high abrasive level and low humectant level? This is also for people who wants to remove tartar or dental plaque

A

Type II

41
Q

Characteristics of toothpaste

T/F: The toothpaste should penetrate into the bristle of the brush, which should form a string when finger is pulled away from ribbon.

A

False. Does not penetrate into the bristle of the brush, does not form a string

42
Q

Toothpaste rheology

T/F: Becomes deformed and flowable with application of minimal stress. Reestablishes its original structure almost instantaneously

A

True

43
Q

T/F: A heterogenous ribbon is formed upon extrusion from the container

A

False. Homogenous

44
Q

T/F: The paste freely flows from open container in the absence of an extrusion pressure.

A

False. Does not flow

45
Q

T/F: A pressure of a squeeze of a whole hand is required to extrude the paste

A

False. minimal effort must be required

46
Q

T/F: The extruded ribbon of the paste breaks sharply and cleanly onto the toothbrush.

A

True

47
Q

T/F: The paste disperse quickly in the mouth and does not feel gummy. The flavor should also release quickly

A

True

48
Q

T/F: The foam rinses from the mouth easily, leaving no residual gummy feeling in the mouth. In addition, spittle is easily rinsed from the sink.

A

True

49
Q

T/F: Dispensing of the paste is
incompatible with the dispensing mechanism.

A

False. Compatible

50
Q

Toothpaste Quality Parameters

A

1.Spreadability
2. Extrudability
3.Foaming property
4.Flavor
5. Preservative Efficacy
6. Viscosity
7.Color
8.pH

51
Q

Efficacy(Performance) Parameters

A

1.Antimicrobial activity
2.Whitening activity
3.Hypersensitivity reduction