EX 4 Drugs Used In The CNS Flashcards

1
Q

Fight or flight

A

Sympathetic

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2
Q

Rest and digest

A

Parasympathetic

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3
Q

7 Major Neurotransmitters

A
  1. Glutamate
  2. GABA
  3. Serotonin
  4. Dopamine.
  5. Norepinephrine
  6. Acetylcholine
  7. Histamine
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4
Q

Major excitatory neurotransmitter derived from glucose coupled by sodium (+) channel

A

Glutamate

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5
Q

Function of glutamate

A

Memory, learning, stress response

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6
Q

GABA stands for

A

Gamma-aminobutyric acid

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7
Q

Major inhibitory neurotransmitter derived from glutamate coupled by chloride (-) channel

A

GABA

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8
Q

Serotonin is aka

A

5-HT (5-hydroxytryptamine)

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9
Q

Derived from tryptophan

A

5-HT

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10
Q

Function of 5-HT

A
  1. Thought process
  2. Mood, wakefulness, sleep
  3. Feeding behavior
  4. Control of sensory transmission
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11
Q

Usually inhibited by antipsychotics

A

Dopamine

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12
Q

Function of dopamine

A
  1. Motor control (nigrostriatal pathway)
  2. Behavioral effect (mesolimbic and mesocortical pathway)
  3. Endocrine control (tuberohypophyseal pathway)
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13
Q

Derived from tyrosine and manipulated by psychiatric drugs

A

Norepinephrine

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14
Q

Function of NE

A
  1. Arousal and mood
  2. Blood pressure regulation
  3. Mimic sympathetic activity
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15
Q

Derived from choline and acetyl-CoA and binds to muscarinic and nicotinic receptor

A

Acetylcholine

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16
Q

Function of acetylcholine

A
  1. Memory
  2. Motor control
17
Q

Function of histamine

A

Wakefulness (Central receptors)

18
Q

Collective term for 5-ht, dopamine, and ne

A

Catecholamines

19
Q

Side effects of histamines

A

Drowsiness

20
Q

Diphenhydramine

A

A histamine