EX 4 Drugs Used In The CNS Flashcards
Fight or flight
Sympathetic
Rest and digest
Parasympathetic
7 Major Neurotransmitters
- Glutamate
- GABA
- Serotonin
- Dopamine.
- Norepinephrine
- Acetylcholine
- Histamine
Major excitatory neurotransmitter derived from glucose coupled by sodium (+) channel
Glutamate
Function of glutamate
Memory, learning, stress response
GABA stands for
Gamma-aminobutyric acid
Major inhibitory neurotransmitter derived from glutamate coupled by chloride (-) channel
GABA
Serotonin is aka
5-HT (5-hydroxytryptamine)
Derived from tryptophan
5-HT
Function of 5-HT
- Thought process
- Mood, wakefulness, sleep
- Feeding behavior
- Control of sensory transmission
Usually inhibited by antipsychotics
Dopamine
Function of dopamine
- Motor control (nigrostriatal pathway)
- Behavioral effect (mesolimbic and mesocortical pathway)
- Endocrine control (tuberohypophyseal pathway)
Derived from tyrosine and manipulated by psychiatric drugs
Norepinephrine
Function of NE
- Arousal and mood
- Blood pressure regulation
- Mimic sympathetic activity
Derived from choline and acetyl-CoA and binds to muscarinic and nicotinic receptor
Acetylcholine