Evolution Lecture 2 Flashcards
Natural selection in action examples and why are they easy to study?
Drug resistance in pathogenic microorganisms, Pesticide resistance, Host-switching in insects. Because they can reproduce often and have strong selective pressure and short generation times.
Selective pressure
An evolutionary force that increases or decreases the reproductive success of a population, which drives natural selection.
If you are resistant then you have what?
A higher fitness and have more offspring.
How does drug resistance work?
A drug does not create resistance pathogens, it selects for resistant individuals already in the population.
How does Warfarin work in rats?
The rat poison interferes with the synthesis of blood-clotting agents. So if they get a cut, they will bled to death. Rats use vitamin K to make blood clots but it gets used up in the process. But rats have an enzyme (vitamin K epoxide reductase) to reconvert the vitamin K back into its active form, and the cycle starts again. But the warfarin blocks enzyme so the vitamin K remains in its active form.
How do rats resist warfarin?
It’s a mutation in a gene that encodes the enzyme. The rats with this gene have more kids and the resistance increases rapidly in populations after poisoning programs introduced. Warfarin will work very well for a while at killing rats, then isn’t anymore.
What happened when they stopped using warfarin?
The amount of rats with resistance to warfarin will go down because that variant doesn’t convert vitamin k very well so they are malnourished, meaning it’s a disadvantage to have that gene with the poison.
Why did the resistant gene spike so quickly?
Because there were probably rats that already had the gene from other populations.
Artificial system
When the human changes the environment.
Artificial selection
When the human interferes with the breeding process.
Soapberry bug example?
Soapberry bugs feed on fruit in southern Florida of original host species. These fruits are bigger, so the bugs have longer beaks to get the seeds from fruits. Then a flatter introduced fruit in central Florida becomes very common. It is difficult for the longer beaked bugs to get the seeds out of this fruit so the shorter beak is now favoured and the average beak length in population falls.
What is the soapberry bug a good example of?
Directional selection
What do the soapberry bug and drug resistance how about natural selection?
It’s editing rather than creating mechanism, so it needs the variation to act on.
Species that produce new generations in short periods of time, evolution by natural selection can occur rapidly.
Contingent on time and place (adaptation to the particular environment).
Evidence for a tree-of-life, and descent with modification?
Homology, Biogeography, Fossil record
Homology
Similarity resulting from common ancestry. It’s different versions of the same thing. Homologs are features that you see in two similar organisms, two species because they share a common ancestor.