evidence-based medicine (EBM) Flashcards
what is the formula for negative likelihood ratio (LR-)?
(1 - sensitivity) / specificity
what is the formula for positive likelihood ratio (LR+)?
sensitivity / (1 - specificity)
which statements are true?
a. Best test to use for ruling out disease is one with largest LR+
b. Best test to use for ruling out disease is one with smallest LR-
c. Best test to use for ruling in disease is one with smallest LR-
d. Best test to use for ruling in disease is one with largest LR+
b. Best test to use for ruling out disease is one with smallest LR-
d. Best test to use for ruling in disease is one with largest LR+
what are Aust R goods evaluated on?
quality, safety, efficacy
what are Aust L goods evaluated on?
quality and safety
what does a skewed funnel plot indicate?
publication bias
what does horizontal line on forest plot represent?
95% confidence interval
bigger line = smaller sample
what does the diamond on forest plot represent?
pooled mean when results are averaged
what do the squares on forest plot represent?
mean
bigger squares = bigger sample
what is sensitivity?
probability of positive test in those with disease
what is specificity?
probability of negative test in those without disease
what is positive likelihood ratio?
probability of positive test in those with disease/probability of positive test in those without disease
what is negative likelihood ratio?
probability of negative test in those with disease/probability of negative test in those without disease
what is positive predictive value?
Probability a person has the disease when the test is positive
what is negative predictive value?
Probability a person does not have the disease when the test is negative