Evasion of host cells

Question 1

Name 4 strategies bacteria can utilise to evade host defences

Answer 1

1. Evasion of phagocytes
2. Killing phagocytes
3. Surviving phagocytes
4. Regulation of host cell survival and immunity

Question 2

Name a bacteria which evades phagocytes

Answer 2

Porphyromonas gingivalis

Question 3

Describw how porphyromonas gingivalis avoids phagocytes

Answer 3

By downregulation of of host cell IL-8. IL-8 attracts neutrophils and thus downregulation of IL-8 prevents entry of phagocytes into the tissue.