Evaluation: Addiction Genes Flashcards

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1
Q

Why are twin studies effective when conducting research into addiction genes?
(the difference between initiation and maintenance)

A
  • They demonstrate the influence of genetic factors in addiction.
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2
Q

Describe Kevin Kendler and Carol Prescott’s 1999 research involving twin studies and cocaine.
(the difference between initiation and maintenance)

A
  • Interviewed nearly 2000 twins.
  • Findings: social and environmental factors influenced whether someone would initiate cocaine use.
  • BUT addiction was more dependent on genetic factors.
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3
Q

What did Kendler and Prescott find regarding concordance rates for cocaine initiation and cocaine dependence?
(the difference between initiation and maintenance)

A
  • Concordance for cocaine addiction: MZ Twins = 54%
    DZ Twins = 42%
  • Concordance for cocaine dependence: MZ Twins = 35%
    DZ Twins = 0%
  • There’s a substantial difference, suggesting a greater role for genetic factors in addiction, rather than the decision to use it.
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4
Q

The relationship between genetics and addiction is more (blank) than it first appears.
(a ‘gene’ for addiction?)

A
  • Complex.
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5
Q

What other genes exist that have been connected to addiction, other than ADH and DRD2?
(a ‘gene’ for addiction?)

A
  • Rsu1.
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6
Q

What did Shamsideen Ojelade et al’s 2015 research into Rsu1 find?
(a ‘gene’ for addiction?)

A
  • Rsu1 gene wasn’t functioning correctly in fruit flies which caused a lowered sensitivity to alcohol.
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7
Q

What did brain imaging testing for Rsu1 in humans find?

a ‘gene’ for addiction?

A
  • Found a relationship between Rsu1 and alcohol dependence.
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8
Q

As a range of genes have been identified, what does this mean for the idea of there being a set ‘gene’ for addiction?
(a ‘gene’ for addiction?)

A
  • Can’t say that there’s a ‘gene’ for addiction.

- Different types of addiction may be caused by different genetic mechanisms.

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9
Q

Why is determinism a key strength of biological explanations?
(determinism)

A
  • Explains why only some become addicted even though many try the behaviour.
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10
Q

What does a determinist view suggest in terms of addiction?

determinism

A
  • A reduced sense of blame upon the addicts as it suggests a lack of control.
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11
Q

Why might a deterministic view of addiction be disadvantageous?
(determinism)

A
  • Person may see addiction as unstoppable consequence of their genetic make-up, meaning that they take less responsibility for their recovery.
  • Taking responsibility is important when battling to overcome addiction.
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12
Q

Why is the idea of addiction genes often criticised?

role of social and cultural factors

A
  • Ignoring roles played by other factors.
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13
Q

What did Kenneth Kendler et al (2000) find out about the heritability of tobacco use?
(role of social and cultural factors)

A
  • Heritability of tobacco use changed over time.
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14
Q

What did Kenneth Kendler et al’s research into the heritability of Swedish twin pairs find?
(role of social and cultural factors)

A
  • Twin pairs born between 1910 and 1958.
  • Women born earlier = little influence of genetic factors.
  • Women born later = Heritability around 60%
  • Role for men = relatively stable.
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15
Q

What might have influenced the difference between the heritability of tobacco use in men and women in Kenneth Kendler’s research?
(role of social and cultural factors)

A
  • Changing attitudes towards women smokers may have influenced the likelihood of genetic predisposition expressing itself.
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16
Q

What did Jason Boardman et al’s 2008 research into siblings and twin pairs find?
(role of social and cultural factors)

A
  • There was a strong genetic component in the onset of smoking behaviour.
  • BUT rate for daily smoking varied across the samples of schools.
17
Q

In Jason Boardman’s research, where was the heritability rate found to be the highest, and why was this?
(role of social and cultural factors)

A
  • In schools where the most popular students were smokers.

- Influence of social factors (peers) impacted whether genetic predisposition expressed itself.

18
Q

How do biological explanations explain addiction?

rejection of the disease model of addiction

A
  • Disease of brain and body.

- Requires treatment like a physical illness.

19
Q

Why does ex-addict and neuroscientist, Marc Lewis, find the view of addiction as a disease unhelpful to addicts? What view does he believe should be followed instead?
(rejection of the disease model of addiction)

A
  • Labling as a disease can damage self-esteem and make them feel helpless in overcoming it.
  • Changes in brain should be considered as a form of learning, not a disease. This view is helpful in overcoming addiction.