Eukaryotic Pathogens Flashcards
Exam 4
How are Protozoa classified?
style of locomotion:
-flagella
-pseudopods
-cilia
How do Mastigophorans move?
-Have flagella
Trichonymptha
type of mastigophoran, symbiotic relationship
-lives in the gut of termites and helps digest cellulose
Trichomonas
type of mastigophoran, symbiotic relationship
lives in the human vagina, controlled by vaginal acidic environment. Thrive if pH becomes basic, can cause sterility.
Giardia Intestinalis
Type of mastigophoran, parasitize
feed off intestinal lining causing disease
-results from easting food/water that is contaminated (usually from feces)
-generates inflammation in large numbers.
-Chronic can cause malnourishment
Amebozoa
have pseudopods, eat and move by extending parts of their bodies.
-found in intestines w/out causing issues mostly
Entamoeba Histolytica
feeds on gut lining
contracted by by eating or drinking fecally contaminated food/water
Amoebic Dysetery
condition caused by Entamoeba histolytica irritation
Ciliates
have cilia to move
Balantidium Coli
only species of ciliate to parasitize humans
-colonizes large intestine to cause diarrhea
What is the common name of Naegleria fowleri?
the brain-eating amoeba
Where are amebo-flagellates found?
warm fresh water and soil
How many forms does Naegleria fowleri exist in nature?
3
Cyst
less than optimal conditions
Trophozoite (ameboid)
favorable conditions, feeding & reproductive form
Flagellate
tail that swims, cannot eat, revert back to trophozoites
How does Naegleria fowleri destroy brain tissue?
by trogocytosis (cell eating)
-attracted to nerve cell chemicals
Where does Apicomplexan’s name come from?
enzymes present in groups of organelles at tips of cells that digest their ways into host
Biological vector of Malaria
Anopheles mosquito
What is Schizogony?
multiple nuclear divisions make multinucleate cell. when the cell divides too quickly it burst host cell.
1st step in the Malarial life cycle:
Asexual phase: sporozoites enter a capillary thru saliva of mosquito
2nd step in the Malarial life cycle:
Exoerythrocytic (liver) phase: invade the liver and develop merozoites
3rd step in the Malarial life cycle:
Erythrocytic phase: merozoites in circulation enter RBC’s and form ringed trophozoite forms & undergoes schizogony
4th step in the Malarial life cycle:
Fever phase: more merozoites are formed the burst out and infect more RBC’s
5th step in the Malarial life cycle:
Gametocyte phase: gametocytes develop in some RBC and are ingested by mosquito
6th step in the Malarial life cycle:
Sexual phase: feralization and sporozoite forms in mosquito
Fungal cell wall composition?
have chitin (nitrogen containing polysaccharide) identical to insects external skeleton
How do fungi get food?
take energy from other organisms alive or dead (heterotrophic)
-don’t ingest their food, digest outside their body by enzymes
Examples of multicellular fungi:
Examples of single-celled fungi:
What causes Cutaneous Mycoses (Ringworm)?
group of fungi called Dermatophytes
in keratin layer and hair and nails from direct contact
1.)Tinea Capitis, 2.)Tinea Barbae, 3.)Tinea Corporis, 4.)Tinea Cruis, 5.)Tinea Pedis, 6.) Tinea Manuum
- scalp
- beard
- body
- groin
- foot
- hand
What causes Superficial Mycoses (sunspots)?
S&S
Malassezia Furfur
normal flora, feed on sebaceous glands
S&S: mild, chronic scaling, pigment production interference,
Candida Auris
Yeast
-“emerging” pathogen in healthcare settings
-person-to-person transmission
-often misidentified, multidrug resistant, can tolerate high salt concentration, avoids neutrophil attacks,
-high mortality in blood infections
Tapeworm Scolex
suckers and hooklets to attach to intestine
Tapeworm Strobilia- proglottids
body, contain reporductive organs of both sex
Enterobius vermicularis
pinworm
Trichinella spiralis
pork roundworm
Ascaris lumbriocoides
common roundworm
Ancylostoma duodenale
hookworm
Taenia species
beef and pork tapeworm
Dipylidium species
dog tapeworms
Diphyllobothrium species
fish tapeworms
Plasmodium
Malaria?
Entamoeba histolytica
amoebic dysentery
Naegleria fowleri
“brain-eating amoeba”